PMID- 27651191
OWN - NLM
STAT- MEDLINE
DCOM- 20180430
LR  - 20230805
IS  - 1008-9292 (Print)
IS  - 1008-9292 (Linking)
VI  - 45
IP  - 3
DP  - 2016 May 25
TI  - [Metabolic syndrome increases Framingham risk score of patients with type 2 
      diabetes mellitus].
PG  - 268-74
AB  - OBJECTIVE: To assess the impact of metabolic syndrome(MS) on Framingham risk 
      score(FRS) in patients with type 2 diabetes mellitus (T2DM). METHODS: The 
      anthropometric and biochemical data of 1708 patients with T2DM admitted in 
      hospital from May 2008 to April 2013 were retrospectively analyzed, including 902 
      males and 806 females with a mean age of 57.1+/-11.8 years (20-79 years). Diagnosis 
      of MS was made according to the criteria of the Adult Treatment Panel Ⅲ Criteria 
      modified for Asians. RESULTS: Compared to non-MS/T2DM patients, MS/T2DM patients 
      had higher waist circumference, body weight, body mass index, systolic and 
      diastolic blood pressure, fasting C peptide, total cholesterol, triglyceride, and 
      LDL-C (P<0.05), while lower HDL-C (P<0.01). Both FRS [13.0(10.0, 15.0) vs 
      11.0(9.0, 13.0) in male,15.0(12.0, 18.0) vs 12.0(6.0, 14.8) in female,P<0.01)] 
      and 10-year cardiovascular risk [12.0%(6.0%, 20.0%) vs 8.0%(5.0%,12.0%) in 
      male,3.0%(1.0%, 6.0%) vs 1.0%(0.0%, 2.8%) in female,P<0.01] were higher in 
      MS/T2DM patients than those in non-MS/T2DM patients.Both FRS and 10-year 
      cardiovascular risk were increased with the components of MS. CONCLUSION: T2DM 
      patients with MS have more cardiovascular risk factors, higher FRS and 10-year 
      cardiovascular risk.
FAU - Meifang, Yao
AU  - Meifang Y
AD  - Department of Endocrinology and Metabolism, the Second Affiliated Hospital, 
      Zhejiang University School of Medicine, Hangzhou 310009, China;Health Management 
      Center, Zhejiang Hospital, Hangzhou 310013, China.
FAU - Xue, Sun
AU  - Xue S
AD  - Department of Endocrinology and Metabolism, the Second Affiliated Hospital, 
      Zhejiang University School of Medicine, Hangzhou 310009, China.
FAU - Jue, Han
AU  - Jue H
AD  - Department of Endocrinology and Metabolism, the Second Affiliated Hospital, 
      Zhejiang University School of Medicine, Hangzhou 310009, China.
FAU - Yina, T U
AU  - Yina TU
AD  - Department of Endocrinology and Metabolism, the Second Affiliated Hospital, 
      Zhejiang University School of Medicine, Hangzhou 310009, China.
FAU - Jie, H E
AU  - Jie HE
AD  - Department of Endocrinology and Metabolism, the Second Affiliated Hospital, 
      Zhejiang University School of Medicine, Hangzhou 310009, China.
FAU - Yiming, Zhao
AU  - Yiming Z
AD  - Department of Endocrinology and Metabolism, the Second Affiliated Hospital, 
      Zhejiang University School of Medicine, Hangzhou 310009, China.
FAU - Hanyu, Lou
AU  - Hanyu L
AD  - Department of Endocrinology and Metabolism, the Second Affiliated Hospital, 
      Zhejiang University School of Medicine, Hangzhou 310009, China.
FAU - Xiaohong, Pang
AU  - Xiaohong P
AD  - Department of Endocrinology and Metabolism, the Second Affiliated Hospital, 
      Zhejiang University School of Medicine, Hangzhou 310009, China.
FAU - Wenheng, Zeng
AU  - Wenheng Z
AD  - Department of Endocrinology and Metabolism, the Second Affiliated Hospital, 
      Zhejiang University School of Medicine, Hangzhou 310009, China.
FAU - Songzhao, Zhang
AU  - Songzhao Z
AD  - Department of Clinical Laboratory, the Second Affiliated Hospital, Zhejiang 
      University School of Medicine, Hangzhou 310009, China.
FAU - Pengfei, Shan
AU  - Pengfei S
AD  - Department of Endocrinology and Metabolism, the Second Affiliated Hospital, 
      Zhejiang University School of Medicine, Hangzhou 310009, China. 
      shanpf95@hotmail.com.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Zhejiang Da Xue Xue Bao Yi Xue Ban
JT  - Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical 
      sciences
JID - 100927946
RN  - 0 (Triglycerides)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Blood Pressure
MH  - Body Mass Index
MH  - Cardiovascular Diseases/*epidemiology
MH  - Diabetes Mellitus, Type 2/*complications
MH  - Female
MH  - Humans
MH  - Male
MH  - Metabolic Syndrome/*complications
MH  - Middle Aged
MH  - Risk Factors
MH  - Triglycerides
MH  - Waist Circumference
MH  - Young Adult
PMC - PMC10396989
EDAT- 2016/09/22 06:00
MHDA- 2018/05/01 06:00
PMCR- 2016/05/25
CRDT- 2016/09/22 06:00
PHST- 2016/09/22 06:00 [entrez]
PHST- 2016/09/22 06:00 [pubmed]
PHST- 2018/05/01 06:00 [medline]
PHST- 2016/05/25 00:00 [pmc-release]
AID - zjdxxbyxb-45-3-268 [pii]
AID - 10.3785/j.issn.1008-9292.2016.05.08 [doi]
PST - ppublish
SO  - Zhejiang Da Xue Xue Bao Yi Xue Ban. 2016 May 25;45(3):268-74. doi: 
      10.3785/j.issn.1008-9292.2016.05.08.