PMID- 27656302
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160922
LR  - 20201001
IS  - 2090-6625 (Print)
IS  - 2090-6633 (Electronic)
VI  - 2016
DP  - 2016
TI  - Q Fever Risk in Patients Treated with Chronic Antitumor Necrosis Factor-Alpha 
      Therapy.
PG  - 4586150
LID - 10.1155/2016/4586150 [doi]
LID - 4586150
AB  - Q fever is a zoonotic bacterial disease caused by Coxiella burnetii. Tumor 
      necrosis factor-alpha (TNF-alpha) plays a pivotal role in the defense against 
      infection with this Gram-negative coccobacillus. Theoretically, patients who are 
      treated with anti-TNF-alpha medications are at risk for developing chronic Q fever. 
      We present two patients who developed Q fever while being treated with anti-TNF-alpha 
      agents and discuss the significance of timely diagnosis of C. burnetii infection 
      in these patients.
FAU - Hirsch, Julianna
AU  - Hirsch J
AUID- ORCID: 0000-0003-2911-2113
AD  - Bruce and Ruth Rappaport Faculty of Medicine, Technion, Haifa, Israel.
FAU - Astrahan, Anna
AU  - Astrahan A
AD  - Department of Internal Medicine A, Bnai Zion Medical Center, Haifa, Israel.
FAU - Odeh, Majed
AU  - Odeh M
AD  - Bruce and Ruth Rappaport Faculty of Medicine, Technion, Haifa, Israel; Department 
      of Internal Medicine A, Bnai Zion Medical Center, Haifa, Israel.
FAU - Elias, Nizar
AU  - Elias N
AD  - Bruce and Ruth Rappaport Faculty of Medicine, Technion, Haifa, Israel; Department 
      of Internal Medicine A, Bnai Zion Medical Center, Haifa, Israel.
FAU - Rosner, Itzhak
AU  - Rosner I
AD  - Bruce and Ruth Rappaport Faculty of Medicine, Technion, Haifa, Israel; Department 
      of Rheumatology, Bnai Zion Medical Center, Haifa, Israel.
FAU - Rimar, Doron
AU  - Rimar D
AD  - Bruce and Ruth Rappaport Faculty of Medicine, Technion, Haifa, Israel; Department 
      of Rheumatology, Bnai Zion Medical Center, Haifa, Israel.
FAU - Kaly, Lisa
AU  - Kaly L
AD  - Bruce and Ruth Rappaport Faculty of Medicine, Technion, Haifa, Israel; Department 
      of Rheumatology, Bnai Zion Medical Center, Haifa, Israel.
FAU - Rozenbaum, Michael
AU  - Rozenbaum M
AD  - Bruce and Ruth Rappaport Faculty of Medicine, Technion, Haifa, Israel; Department 
      of Rheumatology, Bnai Zion Medical Center, Haifa, Israel.
FAU - Boulman, Nina
AU  - Boulman N
AD  - Bruce and Ruth Rappaport Faculty of Medicine, Technion, Haifa, Israel; Department 
      of Rheumatology, Bnai Zion Medical Center, Haifa, Israel.
FAU - Slobodin, Gleb
AU  - Slobodin G
AD  - Bruce and Ruth Rappaport Faculty of Medicine, Technion, Haifa, Israel; Department 
      of Rheumatology, Bnai Zion Medical Center, Haifa, Israel.
LA  - eng
PT  - Journal Article
DEP - 20160830
PL  - Egypt
TA  - Case Rep Infect Dis
JT  - Case reports in infectious diseases
JID - 101573243
PMC - PMC5021454
EDAT- 2016/09/23 06:00
MHDA- 2016/09/23 06:01
PMCR- 2016/08/30
CRDT- 2016/09/23 06:00
PHST- 2016/07/16 00:00 [received]
PHST- 2016/08/22 00:00 [accepted]
PHST- 2016/09/23 06:00 [entrez]
PHST- 2016/09/23 06:00 [pubmed]
PHST- 2016/09/23 06:01 [medline]
PHST- 2016/08/30 00:00 [pmc-release]
AID - 10.1155/2016/4586150 [doi]
PST - ppublish
SO  - Case Rep Infect Dis. 2016;2016:4586150. doi: 10.1155/2016/4586150. Epub 2016 Aug 
      30.