PMID- 27664723
OWN - NLM
STAT- MEDLINE
DCOM- 20170406
LR  - 20180512
IS  - 1618-0623 (Electronic)
IS  - 0944-5013 (Linking)
VI  - 192
DP  - 2016 Nov
TI  - Phytogenic synthesis of silver nanoparticles, optimization and evaluation of in 
      vitro antifungal activity against human and plant pathogens.
PG  - 52-64
LID - S0944-5013(16)30316-0 [pii]
LID - 10.1016/j.micres.2016.06.004 [doi]
AB  - An attempt was made to synthesis of biocompatible silver nanoparticles from ten 
      different Cassia spp. Among them, Cassia roxburghii aqueous leaf extract 
      supported the synthesis of highly efficient and stable AgNPs. The synthesis of 
      AgNPs was optimized at different physico-chemical condition and highly stable 
      AgNPs were synthesized with 1.0mL of C. roxburghii leaf extract, pH 7.0, 1.0mM 
      AgNO3 and at 37 degrees C. The synthesized AgNPs were characterized by XPS, DLS and ZETA 
      potential. DLS and ZETA potential analysis, the average AgNPs size was 35nm and 
      the zeta potential was -18.3mV. The AgNPs exhibit higher antifungal activity when 
      compared with the conventional antifungal drug amphotericin B against all the 
      tested human fungal pathogens such as Aspergillus niger, Aspergillus fumigatus, 
      Aspergillus flavus, Penicillium sp., Candida albicans and the plant pathogens 
      such as Rhizoctonia solani, Fusarium oxysporum and Curvularia sp. Scanning 
      electron microscope (SEM) analysis showed distinct structural changes in the cell 
      membranes of C. albicans upon AgNPs treatment. These results suggest that 
      phytosynthesized AgNPs could be used as effective growth inhibitors in 
      controlling various human and plant diseases caused by fungi.
CI  - Copyright (c) 2016 Elsevier GmbH. All rights reserved.
FAU - Balashanmugam, P
AU  - Balashanmugam P
AD  - Centre for Advanced Studies in Botany, University of Madras, Chennai 600 025, 
      India. Electronic address: biobala17@gmail.com.
FAU - Balakumaran, M D
AU  - Balakumaran MD
AD  - Centre for Advanced Studies in Botany, University of Madras, Chennai 600 025, 
      India.
FAU - Murugan, R
AU  - Murugan R
AD  - Centre for Advanced Studies in Botany, University of Madras, Chennai 600 025, 
      India.
FAU - Dhanapal, K
AU  - Dhanapal K
AD  - Department of Nuclear Physics, University of Madras, Chennai 600 025, India.
FAU - Kalaichelvan, P T
AU  - Kalaichelvan PT
AD  - Centre for Advanced Studies in Botany, University of Madras, Chennai 600 025, 
      India.
LA  - eng
PT  - Journal Article
DEP - 20160628
PL  - Germany
TA  - Microbiol Res
JT  - Microbiological research
JID - 9437794
RN  - 0 (Antifungal Agents)
RN  - 0 (Phytochemicals)
RN  - 0 (Plant Extracts)
RN  - 3M4G523W1G (Silver)
RN  - 95IT3W8JZE (Silver Nitrate)
SB  - IM
MH  - *Antifungal Agents/administration & dosage/chemistry
MH  - Fungi/*drug effects
MH  - Humans
MH  - Hydrogen-Ion Concentration
MH  - *Metal Nanoparticles/administration & dosage/chemistry/ultrastructure
MH  - Microbial Sensitivity Tests
MH  - Mycoses/microbiology
MH  - Photoelectron Spectroscopy
MH  - Phytochemicals/administration & dosage/chemistry
MH  - Plant Diseases/microbiology
MH  - *Plant Extracts/administration & dosage/chemistry
MH  - *Silver/administration & dosage/chemistry
MH  - Silver Nitrate
MH  - Temperature
OTO - NOTNLM
OT  - AgNPs
OT  - Antifungal activity
OT  - Phytopathogenic fungi
OT  - XPS
EDAT- 2016/09/25 06:00
MHDA- 2017/04/07 06:00
CRDT- 2016/09/25 06:00
PHST- 2016/02/26 00:00 [received]
PHST- 2016/05/30 00:00 [revised]
PHST- 2016/06/04 00:00 [accepted]
PHST- 2016/09/25 06:00 [entrez]
PHST- 2016/09/25 06:00 [pubmed]
PHST- 2017/04/07 06:00 [medline]
AID - S0944-5013(16)30316-0 [pii]
AID - 10.1016/j.micres.2016.06.004 [doi]
PST - ppublish
SO  - Microbiol Res. 2016 Nov;192:52-64. doi: 10.1016/j.micres.2016.06.004. Epub 2016 
      Jun 28.