PMID- 27669506
OWN - NLM
STAT- MEDLINE
DCOM- 20170208
LR  - 20191210
IS  - 1873-376X (Electronic)
IS  - 1570-0232 (Linking)
VI  - 1035
DP  - 2016 Nov 1
TI  - Multi-mycotoxins analysis in Pheretima using ultra-high-performance liquid 
      chromatography tandem mass spectrometry based on a modified QuEChERS method.
PG  - 31-41
LID - S1570-0232(16)30860-1 [pii]
LID - 10.1016/j.jchromb.2016.09.022 [doi]
AB  - A sensitive and high-throughput method was established and validated for the 
      simultaneous determination of 22 mycotoxins in Pheretima aspergillum (E.Perrier) 
      and Pheretima guillelmi (Michaelsen). A modified Quick Easy Cheap Effective 
      Rugged and Safe (QuEChERS) method was used for sample preparation with recoveries 
      ranging from 73% to 105% with relative standard deviations (RSDs) <8.0% for all 
      target analytes. Ultra-high-performance liquid chromatography coupled with triple 
      quadrupole mass spectrometry (UHPLC-MS/MS) was applied for separation and 
      detection in ESI (+) and ESI (-) modes with the limits of detection (LOD) in the 
      range of 0.05-10mugkg(-1). The 22 compounds could be accurately quantified in the 
      0.5-1000mugkg(-1) concentration range with correlation coefficients >0.99. In all 
      cases, the intra- and inter-day precisions were lower than 6% and 10%, 
      respectively. Matrix-matched calibration was utilized for quantification purposes 
      to compensate for the matrix effects. Furthermore, the established method was 
      successfully applied in 17 batches of normal real samples collected from 
      different areas of China and 2 batches of moldy samples due to improper storage, 
      only mold-contaminated samples were confirmed to have fumonisin B1 (FB1) and 
      fumonisin B2 (FB2) contamination at 2.54-3.78mugkg(-1). The constructed method 
      could serve as a practical application of the UHPLC-MS/MS method for the trace 
      analysis of multiple mycotoxins in complex matrixes, especially for those with 
      high lipid contents.
CI  - Copyright (c) 2016 Elsevier B.V. All rights reserved.
FAU - Zhang, Sisi
AU  - Zhang S
AD  - School of Pharmacy, Fudan University, No. 826 Zhangheng Road, Pudong New Distr., 
      Shanghai 201203, China; Shanghai Institute for Food and Drug Control, No. 1500 
      Zhangheng Road, Pudong New Distr., Shanghai 201203, China. Electronic address: 
      14211030033@fudan.edu.cn.
FAU - Lu, Jiwei
AU  - Lu J
AD  - Shanghai Institute for Food and Drug Control, No. 1500 Zhangheng Road, Pudong New 
      Distr., Shanghai 201203, China. Electronic address: lujiwei1011@163.com.
FAU - Wang, Shaomin
AU  - Wang S
AD  - Shanghai Institute for Food and Drug Control, No. 1500 Zhangheng Road, Pudong New 
      Distr., Shanghai 201203, China. Electronic address: wangshaomin2008@163.com.
FAU - Mao, Dan
AU  - Mao D
AD  - Shanghai Institute for Food and Drug Control, No. 1500 Zhangheng Road, Pudong New 
      Distr., Shanghai 201203, China. Electronic address: m21944@126.com.
FAU - Miao, Shui
AU  - Miao S
AD  - Shanghai Institute for Food and Drug Control, No. 1500 Zhangheng Road, Pudong New 
      Distr., Shanghai 201203, China. Electronic address: qmiao2008@163.com.
FAU - Ji, Shen
AU  - Ji S
AD  - Shanghai Institute for Food and Drug Control, No. 1500 Zhangheng Road, Pudong New 
      Distr., Shanghai 201203, China. Electronic address: jishen2016@126.com.
LA  - eng
PT  - Journal Article
PT  - Validation Study
DEP - 20160920
PL  - Netherlands
TA  - J Chromatogr B Analyt Technol Biomed Life Sci
JT  - Journal of chromatography. B, Analytical technologies in the biomedical and life 
      sciences
JID - 101139554
RN  - 0 (Mycotoxins)
SB  - IM
MH  - Chromatography, High Pressure Liquid/*methods
MH  - *Medicine, Chinese Traditional
MH  - Mycotoxins/*analysis
MH  - Tandem Mass Spectrometry/*methods
OTO - NOTNLM
OT  - Mycotoxins
OT  - Pheretima
OT  - QuEChERS
OT  - UHPLC-MS/MS
EDAT- 2016/09/27 06:00
MHDA- 2017/02/09 06:00
CRDT- 2016/09/27 06:00
PHST- 2016/06/13 00:00 [received]
PHST- 2016/09/13 00:00 [revised]
PHST- 2016/09/14 00:00 [accepted]
PHST- 2016/09/27 06:00 [pubmed]
PHST- 2017/02/09 06:00 [medline]
PHST- 2016/09/27 06:00 [entrez]
AID - S1570-0232(16)30860-1 [pii]
AID - 10.1016/j.jchromb.2016.09.022 [doi]
PST - ppublish
SO  - J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Nov 1;1035:31-41. doi: 
      10.1016/j.jchromb.2016.09.022. Epub 2016 Sep 20.