PMID- 27671176 OWN - NLM STAT- MEDLINE DCOM- 20170630 LR - 20170630 IS - 1681-7168 (Electronic) IS - 1022-386X (Linking) VI - 26 IP - 9 DP - 2016 Sep TI - Peripartum Cardiomyopathy in a Pakistani Cohort. PG - 740-3 AB - OBJECTIVE: To describe the demographics, risk factors, and clinical presentation in Pakistani patients with peripartum cardiomyopathy. STUDY DESIGN: A descriptive observational study. PLACE AND DURATION OF STUDY: Rawalpindi Institute of Cardiology, Rawalpindi, from June 2014 to June 2015. METHODOLOGY: Seventy patients meeting criteria of peripartum cardiomyopathy were included in the study. Adetailed history, physical examination and investigations were done. Epidemiologic data, risk factors, New York Heart Association (NYHA) class and echocardiographic findings were recorded. Statistical analyses were done using SPSS version 19. RESULTS: The mean age was 28.66 +/-4.57 years. Mean parity and weight was 3.04 +/-1.7 and 60.97 +/-12.40 Kg, respectively. Fifty-five (78.6%) cases were diagnosed in the postpartum period. Thirty-three (50.8%) and 31 patients (44.7%) presented in NYHA- III and IV classes, respectively. Pregnancy-induced hypertension was seen in 16 (22.9%) cases, diabetes in 6 (8.6%), and twin pregnancy in 2 (2.9%) cases. The mean hemoglobin and brain natriuretic peptide (BNP) was 11.26 +/-1.61 gm/dl and 1583.70 +/-1237.65 pg/ml, respectively. Echocardiography showed mean ejection fraction of 21.74 +/-7.45%. Left ventricle systolic and diastolic diameters were 53.71 +/-9.74 mm and 63.37 +/-8.48 mm, respectively. CONCLUSION: Peripartum cardiomyopathy was seen in younger women with higher parity and pregnancy induced hypertension, often manifesting in the postpartum period with NHYAclass III and IV status. FAU - Munir, Rubab AU - Munir R AD - Department of Obstetric and Gynecology,Rawalpindi Institute of Cardiology, Rawal Road, Rawalpindi. FAU - Hussain, Sajjad AU - Hussain S AD - Department of Cardiology,Rawalpindi Institute of Cardiology, Rawal Road, Rawalpindi. FAU - Kayani, Azhar Mahmood AU - Kayani AM AD - Department of Cardiology,Rawalpindi Institute of Cardiology, Rawal Road, Rawalpindi. LA - eng PT - Journal Article PT - Observational Study PL - Pakistan TA - J Coll Physicians Surg Pak JT - Journal of the College of Physicians and Surgeons--Pakistan : JCPSP JID - 9606447 RN - 114471-18-0 (Natriuretic Peptide, Brain) SB - IM MH - Adolescent MH - Adult MH - Cardiomyopathy, Dilated/*diagnosis/epidemiology MH - Diabetes Mellitus/epidemiology MH - Echocardiography MH - Female MH - Hospitals, University MH - Humans MH - Hypertension, Pregnancy-Induced/epidemiology MH - Maternal Age MH - Natriuretic Peptide, Brain/blood MH - Pakistan/epidemiology MH - Parity MH - Postpartum Period MH - Pregnancy MH - Pregnancy Complications, Cardiovascular/*diagnosis/epidemiology/etiology MH - Pregnancy Outcome MH - Risk Factors MH - Treatment Outcome MH - Young Adult EDAT- 2016/09/28 06:00 MHDA- 2017/07/01 06:00 CRDT- 2016/09/28 06:00 PHST- 2015/08/03 00:00 [received] PHST- 2016/08/22 00:00 [accepted] PHST- 2016/09/28 06:00 [entrez] PHST- 2016/09/28 06:00 [pubmed] PHST- 2017/07/01 06:00 [medline] AID - 040579197 [pii] PST - ppublish SO - J Coll Physicians Surg Pak. 2016 Sep;26(9):740-3.