PMID- 27683283 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20191120 IS - 1741-2854 (Electronic) IS - 0020-7640 (Linking) VI - 62 IP - 7 DP - 2016 Nov TI - Duration of untreated psychosis in an Egyptian sample: Sociodemographic and clinical variables. PG - 661-671 LID - 10.1177/0020764016670429 [doi] AB - BACKGROUND: Duration of untreated psychosis (DUP) has been considered as a poor prognostic factor for psychotic disorder. Several studies have been investigating different predictors of DUP in Western countries, while in Egypt only a few studies have examined various predictors of DUP. AIMS: To study DUP in Egyptian patients with psychotic disorders and to investigate how certain illnesses, patient, socio-cultural risk factors and help-seeking behaviour are correlated with prolonged DUP. METHOD: The sample included 100 patients with Diagnostic and Statistical Manual of Mental Disorders (4th ed., text rev.; DSM-IV-TR) diagnosis of psychotic disorder were selected and interviewed to assess DUP. They were interviewed using the Structured Clinical Interview for DSM-IV axis I disorders (SCID-I), Positive and Negative Syndrome Scale (PANSS) and Global Assessment of Functioning (GAF) scale. RESULTS: Mean (+/-standard deviation ( SD)) of DUP was found to be 36.93(+/-45.27) months. DUP was correlated with various sociodemographic and clinical variables. Following log transformation of DUP, correlation with PANSS scores was done and revealed highly significant statistical relation of DUP to PANSS negative and PANSS positive scores. In linear regression analysis, it was found that age of patients, the age of onset, residence, being illiterate, the insidious mode of onset, negative family history of psychiatric disorder and the severity of illness as indicated by PANSS are among DUP predictors. CONCLUSION: Longer DUP results from multiple patient- and illness-related factors. This has many implications in targeting early intervention with specific consideration to cultural factors. FAU - Okasha, Tarek AU - Okasha T AD - WHO Collaborating Centre for Mental Health Research and Training, Institute of Psychiatry, Ain Shams University, Cairo, Egypt. FAU - Zaki, Nivert AU - Zaki N AD - WHO Collaborating Centre for Mental Health Research and Training, Institute of Psychiatry, Ain Shams University, Cairo, Egypt. FAU - Meguid, Marwa Abd El AU - Meguid MAE AD - WHO Collaborating Centre for Mental Health Research and Training, Institute of Psychiatry, Ain Shams University, Cairo, Egypt. FAU - El-Missiry, Marwa AU - El-Missiry M AD - WHO Collaborating Centre for Mental Health Research and Training, Institute of Psychiatry, Ain Shams University, Cairo, Egypt. FAU - Sabry, Walaa AU - Sabry W AD - WHO Collaborating Centre for Mental Health Research and Training, Institute of Psychiatry, Ain Shams University, Cairo, Egypt. FAU - Ismaeil, Mostafa Kamel AU - Ismaeil MK AD - WHO Collaborating Centre for Mental Health Research and Training, Institute of Psychiatry, Ain Shams University, Cairo, Egypt. FAU - Fouad, Samar M AU - Fouad SM AD - WHO Collaborating Centre for Mental Health Research and Training, Institute of Psychiatry, Ain Shams University, Cairo, Egypt. LA - eng PT - Journal Article DEP - 20160928 PL - England TA - Int J Soc Psychiatry JT - The International journal of social psychiatry JID - 0374726 OTO - NOTNLM OT - Duration of untreated psychosis OT - predicting factors OT - psychotic disorder OT - schizophrenia OT - traditional healer EDAT- 2016/09/30 06:00 MHDA- 2016/09/30 06:01 CRDT- 2016/09/30 06:00 PHST- 2016/09/30 06:00 [pubmed] PHST- 2016/09/30 06:01 [medline] PHST- 2016/09/30 06:00 [entrez] AID - 0020764016670429 [pii] AID - 10.1177/0020764016670429 [doi] PST - ppublish SO - Int J Soc Psychiatry. 2016 Nov;62(7):661-671. doi: 10.1177/0020764016670429. Epub 2016 Sep 28.