PMID- 27687259 OWN - NLM STAT- MEDLINE DCOM- 20170323 LR - 20220311 IS - 1439-0507 (Electronic) IS - 0933-7407 (Linking) VI - 60 IP - 2 DP - 2017 Feb TI - Spontaneous pneumothorax in paracoccidioidomycosis patients from an endemic area in Midwestern Brazil. PG - 124-128 LID - 10.1111/myc.12571 [doi] AB - Paracoccidioidomycosis (PCM) is the most important systemic mycosis in Latin America. About 80% of PCM patients are present with its chronic form. The lungs are affected in most patients with the chronic form; however, pleural involvement has rarely been reported. We describe nine cases of PCM that presented with lung involvement and spontaneous pneumothorax. All patients, except one whose condition was not investigated, were smokers. PCM was diagnosed during the pneumothorax episode in three patients, and from 3 to 16 years before the pneumothorax episode in six patients. A total of six patients underwent chest drainage and one died as a direct result of the pneumothorax. We suggest that pneumothorax, although rare, should be considered in PCM patients who present with suddenly worsening dyspnoea. PCM should also be investigated in cases of pneumothorax in adult men from mycosis-endemic areas. CI - (c) 2016 Blackwell Verlag GmbH. FAU - Cabrera, Lucas G G AU - Cabrera LG AD - Faculty of Medicine of Sao Jose do Rio Preto, Universidade Federal de Mato Grosso do Sul, Sao Jose do Rio Preto, Sao Paulo, Brazil. FAU - Santos, Aline F AU - Santos AF AD - Centro Universitario Unigran Capital, Campo Grande, Mato Grosso do Sul, Brazil. FAU - Andrade, Ursulla V AU - Andrade UV AD - Dom Bosco Catholic University, Campo Grande, Mato Grosso do Sul, Brazil. FAU - Guedes, Carlos Ivan A AU - Guedes CI AD - Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil. FAU - Oliveira, Sandra M V L AU - Oliveira SM AD - Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil. FAU - Chang, Marilene R AU - Chang MR AD - Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil. FAU - Mendes, Rinaldo P AU - Mendes RP AUID- ORCID: 0000-0002-0661-5917 AD - State University "Julio de Mesquita Filho", Botucatu, Sao Paulo, Brazil. FAU - Paniago, Anamaria M M AU - Paniago AM AD - Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil. LA - eng PT - Case Reports PT - Journal Article DEP - 20160930 PL - Germany TA - Mycoses JT - Mycoses JID - 8805008 RN - 0 (Antifungal Agents) RN - 7XU7A7DROE (Amphotericin B) RN - 8064-90-2 (Trimethoprim, Sulfamethoxazole Drug Combination) SB - IM MH - Adult MH - Amphotericin B/therapeutic use MH - Antifungal Agents/therapeutic use MH - Biopsy MH - Brazil/epidemiology MH - Drainage MH - *Endemic Diseases MH - Fatal Outcome MH - Humans MH - Lung/microbiology/pathology MH - Male MH - Middle Aged MH - Paracoccidioides/drug effects/isolation & purification MH - Paracoccidioidomycosis/*diagnosis/drug therapy/epidemiology/*microbiology MH - Pneumothorax/diagnostic imaging/*microbiology MH - Smoking/adverse effects MH - Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic use OTO - NOTNLM OT - Paracoccidioides spp OT - lung mycosis OT - paracoccidioidomycosis OT - pneumothorax EDAT- 2016/10/01 06:00 MHDA- 2017/03/24 06:00 CRDT- 2016/10/01 06:00 PHST- 2016/05/17 00:00 [received] PHST- 2016/07/02 00:00 [revised] PHST- 2016/09/05 00:00 [accepted] PHST- 2016/10/01 06:00 [pubmed] PHST- 2017/03/24 06:00 [medline] PHST- 2016/10/01 06:00 [entrez] AID - 10.1111/myc.12571 [doi] PST - ppublish SO - Mycoses. 2017 Feb;60(2):124-128. doi: 10.1111/myc.12571. Epub 2016 Sep 30.