PMID- 27701480
OWN - NLM
STAT- MEDLINE
DCOM- 20171218
LR  - 20181113
IS  - 1680-0745 (Electronic)
IS  - 1995-1892 (Print)
IS  - 1015-9657 (Linking)
VI  - 28
IP  - 2
DP  - 2017 Mar/Apr 23
TI  - Factors associated with early mortality in haemodialysis patients undergoing 
      coronary artery bypass surgery.
PG  - 108-111
LID - 10.5830/CVJA-2016-066 [doi]
AB  - INTRODUCTION: Coronary artery bypass grafting (CABG) results in higher morbidity 
      and mortality rates in end-stage renal disease (ESRD) patient populations than in 
      patients with normal renal function. This study aimed to identify the early 
      results of CABG performed on ESRD patients, and the factors that affected the 
      mortality rates of those patients. METHODS: A retrospective evaluation of our 
      hospital database revealed 84 haemodialysis-receiving patients who underwent CABG 
      during the years 2006 to 2012. Mortality was observed in 21 patients (group 1), 
      and this group was compared with the remaining patients (group 2) for 
      peri-operative parameters such as age, EuroSCORE, functional capacity, myocardial 
      infarction, use of inotropes and completeness of revascularisation. RESULTS: The 
      study included 60 male (71.4%) and 24 female patients (28.6%); the participants' 
      mean age was 59.50 +/- 9.93 years. The pre-operative additive EuroSCORE was 7.96 +/- 
      2.88 (range: 2-18). Pre-operative functional capacity was impaired in 35.7% of 
      the patients [New York Heart Association (NYHA) classes III-IV]. Mean age and 
      preoperative EuroSCORE values of group 1 were significantly higher than those of 
      group 2. Impaired functional capacity (NHYA classes III-IV) was also associated 
      with mortality (OR: 3.333; 95% CI: 1.199-9.268). Fifty-four patients (64.3%) 
      underwent on-pump CABG procedures, and 30 (35.7%) underwent off-pump CABG 
      procedures. The study found no statistically significant difference in mortality 
      rates between these two techniques. Mortality occurred in 12 patients (22.2%) in 
      the on-pump group and in nine (30%) in the off-pump group. Complete 
      revascularisation was performed on 46 patients (85.2%) in the on-pump group and 
      seven (23.3%) in the off-pump group (p < 0.001). CONCLUSION: Advanced age, 
      impaired NYHA functional capacity and pre-operative hypertension were 
      determinative for early-term surgical mortality. An on-pump surgical technique is 
      recommended to ensure completeness of revascularisation.
FAU - Cevirme, Deniz
AU  - Cevirme D
AD  - Department of Cardiovascular Surgery, Kartal Kosuyolu Heart and Research 
      Hospital, Istanbul, Turkey.
FAU - Adademir, Taylan
AU  - Adademir T
AD  - Department of Cardiovascular Surgery, Kartal Kosuyolu Heart and Research 
      Hospital, Istanbul, Turkey. Email: taylanadademir@gmail.com.
FAU - Aksut, Mehmet
AU  - Aksut M
AD  - Department of Cardiovascular Surgery, Kartal Kosuyolu Heart and Research 
      Hospital, Istanbul, Turkey.
FAU - Orki, Tulay
AU  - Orki T
AD  - Department of Anesthesiology, Kartal Kosuyolu Heart and Research Hospital, 
      Istanbul, Turkey.
FAU - Cakalagaoglu, Kamil Canturk
AU  - Cakalagaoglu KC
AD  - Department of Cardiovascular Surgery, Kartal Kosuyolu Heart and Research 
      Hospital, Istanbul, Turkey.
FAU - Alp, Mete
AU  - Alp M
AD  - Department of Cardiovascular Surgery, Kartal Kosuyolu Heart and Research 
      Hospital, Istanbul, Turkey.
FAU - Kirali, Kaan
AU  - Kirali K
AD  - Department of Cardiovascular Surgery, Kartal Kosuyolu Heart and Research 
      Hospital, Istanbul, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20160722
PL  - South Africa
TA  - Cardiovasc J Afr
JT  - Cardiovascular journal of Africa
JID - 101313864
SB  - IM
MH  - Age Factors
MH  - Aged
MH  - Cardiopulmonary Bypass/adverse effects/mortality
MH  - Chi-Square Distribution
MH  - Coronary Artery Bypass/adverse effects/*mortality
MH  - Coronary Artery Bypass, Off-Pump/adverse effects/mortality
MH  - Coronary Artery Disease/diagnosis/mortality/*surgery
MH  - Databases, Factual
MH  - Female
MH  - Humans
MH  - Hypertension/mortality
MH  - Kidney Failure, Chronic/diagnosis/mortality/*therapy
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Odds Ratio
MH  - Patient Selection
MH  - Renal Dialysis/adverse effects/*mortality
MH  - Retrospective Studies
MH  - Risk Assessment
MH  - Risk Factors
MH  - Time Factors
MH  - Treatment Outcome
PMC - PMC5488051
EDAT- 2016/10/05 06:00
MHDA- 2017/12/19 06:00
PMCR- 2017/03/01
CRDT- 2016/10/05 06:00
PHST- 2015/12/07 00:00 [received]
PHST- 2016/05/29 00:00 [accepted]
PHST- 2016/10/05 06:00 [pubmed]
PHST- 2017/12/19 06:00 [medline]
PHST- 2016/10/05 06:00 [entrez]
PHST- 2017/03/01 00:00 [pmc-release]
AID - 10.5830/CVJA-2016-066 [doi]
PST - ppublish
SO  - Cardiovasc J Afr. 2017 Mar/Apr 23;28(2):108-111. doi: 10.5830/CVJA-2016-066. Epub 
      2016 Jul 22.