PMID- 2770525 OWN - NLM STAT- MEDLINE DCOM- 19891006 LR - 20151028 IS - 0882-889X (Print) IS - 0882-889X (Linking) VI - 12 IP - 1-3 DP - 1989 TI - Electrophysiological discrimination between retinal and optic nerve disorders. PG - 69-73 AB - In this study we show how the Pattern ERG (PERG) can be used to distinguish between optic nerve and retinal disease. Records from eyes with RBN and delayed visual evoked responses are compared with those recorded from the normal fellow eyes. In optic nerve disease there is a selective reduction of the later negative component of the response. PERG's were also recorded from patients with mild diabetic retinopathy. These were divided into three groups on the basis of the delay in their Visual Evoked Potential (VEP). The amplitude of both positive and negative components fall with increasing severity of the disease thus showing that the abnormally long delau in VEP found in some cases is due to retinal disease rather than optic nerve disease. FAU - Ryan, S AU - Ryan S AD - Department of Clinical Ophthalmology, Institute of Ophthalmology, London, England. FAU - Arden, G B AU - Arden GB FAU - Weinstein, G W AU - Weinstein GW LA - eng GR - 1 RO1 EY05 984 O1A1/EY/NEI NIH HHS/United States PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - Metab Pediatr Syst Ophthalmol (1985) JT - Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985) JID - 8800197 SB - IM MH - Adolescent MH - Adult MH - Diagnosis, Differential MH - Electrophysiology MH - Electroretinography MH - *Evoked Potentials, Visual MH - Humans MH - Middle Aged MH - Optic Nerve Diseases/*diagnosis MH - Retinal Diseases/*diagnosis EDAT- 1989/01/01 00:00 MHDA- 1989/01/01 00:01 CRDT- 1989/01/01 00:00 PHST- 1989/01/01 00:00 [pubmed] PHST- 1989/01/01 00:01 [medline] PHST- 1989/01/01 00:00 [entrez] PST - ppublish SO - Metab Pediatr Syst Ophthalmol (1985). 1989;12(1-3):69-73.