PMID- 27707673
OWN - NLM
STAT- MEDLINE
DCOM- 20170210
LR  - 20170210
IS  - 1950-6112 (Electronic)
IS  - 0003-3898 (Linking)
VI  - 74
IP  - 5
DP  - 2016 Oct 1
TI  - Cytogenetics in the management of multiple myeloma: an update by the Groupe 
      francophone de cytogenetique hematologique (GFCH).
PG  - 588-595
AB  - Cytogenetics of multiple myeloma has evolved in recent years by the emergence of 
      Interphasic fluorescence in situ hybridization (FISH) performed on sorted plasma 
      cells detecting abnormalities independently of a proliferative and infiltrative 
      index. Cytogenetic analysis plays a major part in the risk stratification of 
      myeloma diagnosis due to prognostic impact of various cytogenetic abnormalities 
      as well as to the association between emerging therapeutic approaches in MM. 
      Thus, practice guidelines now recommend interphasic FISH or alternative molecular 
      technics as the initial analysis for multiple myeloma. The Groupe francophone de 
      cytogenetique hematologique (GFCH) proposes in this issue an update of managing 
      multiple myeloma cytogenetics.
FAU - Daudignon, Agnes
AU  - Daudignon A
AD  - UF de cytogenetique hematologique, Pole biologie-hygiene, Valenciennes, France.
FAU - Quilichini, Benoit
AU  - Quilichini B
AD  - Service de cytogenetique, Laboratoire Biomnis, Lyon, France.
FAU - Ameye, Genevieve
AU  - Ameye G
AD  - Centre de genetique humaine, Cliniques universitaires St-Luc-Universite 
      catholique de Louvain, Bruxelles, Belgique.
FAU - Poirel, Helene
AU  - Poirel H
AD  - Centre de genetique humaine, Cliniques universitaires St-Luc & de Duve 
      Institute-Universite catholique de Louvain, Bruxelles, Belgique.
FAU - Bastard, Christian
AU  - Bastard C
AD  - Departement de genetique, Centre Henri Becquerel, Rouen, France.
FAU - Terre, Christine
AU  - Terre C
AD  - Laboratoire de cytogenetique, Centre de transfusion sanguine, Le Chesnay, France.
LA  - eng
PT  - Journal Article
PT  - Practice Guideline
PT  - Review
TT  - Place de la cytogenetique dans la prise en charge du myelome multiple : 
      actualisation par le Groupe francophone de cytogenetique hematologique (GFCH).
PL  - France
TA  - Ann Biol Clin (Paris)
JT  - Annales de biologie clinique
JID - 2984690R
SB  - IM
MH  - Cytogenetic Analysis/methods/*standards
MH  - France
MH  - Hematology/organization & administration/standards/trends
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Multiple Myeloma/diagnosis/genetics/*therapy
MH  - Societies, Medical/organization & administration/standards
OTO - NOTNLM
OT  - FISH
OT  - cytogenetic
OT  - myeloma
OT  - plasma cells sorted
EDAT- 2016/10/07 06:00
MHDA- 2017/02/12 06:00
CRDT- 2016/10/07 06:00
PHST- 2016/10/07 06:00 [entrez]
PHST- 2016/10/07 06:00 [pubmed]
PHST- 2017/02/12 06:00 [medline]
AID - abc.2016.1178 [pii]
AID - 10.1684/abc.2016.1178 [doi]
PST - ppublish
SO  - Ann Biol Clin (Paris). 2016 Oct 1;74(5):588-595. doi: 10.1684/abc.2016.1178.