PMID- 27716877
OWN - NLM
STAT- MEDLINE
DCOM- 20170206
LR  - 20181202
IS  - 2038-2529 (Electronic)
IS  - 0300-8916 (Linking)
VI  - 102
IP  - Suppl. 2
DP  - 2016 Nov 11
TI  - Simultaneous integrated bilateral breast and nodal irradiation with volumetric 
      arc therapy: case report and literature review.
LID - 10.5301/tj.5000568 [doi]
AB  - AIM: For simultaneous bilateral breast cancer (SBBC) treatment, conventional 
      radiotherapy (RT) has a number of critical shortcomings. Thus, the usefulness of 
      volumetric arc therapy (VMAT) for SBBC is undeniable. CASE REPORT: A 34-year-old 
      woman with SBBC received neoadjuvant chemotherapy followed by breast-conserving 
      surgery and bilateral lymph node dissection. Given the conservative surgery and 
      the nodal involvement after neoadjuvant chemotherapy, bilateral adjuvant RT to 
      the breasts and regional nodes with doses of 50 Gy in 25 fractions and a 
      simultaneous integrated boost (SIB) of 60 Gy to the surgical bed was proposed. 
      Monoisocentric VMAT using 2 pairs of arcs was performed with adequate target dose 
      coverage and low doses to the organs at risk. The results of this case were 
      compared with those of previous studies in terms of RT technique and irradiated 
      volumes. CONCLUSIONS: VMAT is feasible and safe in the treatment of SBBC with SIB 
      and nodal irradiation.
FAU - Fiorentino, Alba
AU  - Fiorentino A
AD  - Department of Radiation Oncology, Sacro Cuore Don Calabria Hospital, Negrar 
      (Verona) - Italy.
FAU - Tebano, Umberto
AU  - Tebano U
AD  - Department of Radiation Oncology, Sacro Cuore Don Calabria Hospital, Negrar 
      (Verona) - Italy.
FAU - Ruggieri, Ruggero
AU  - Ruggieri R
AD  - Department of Radiation Oncology, Sacro Cuore Don Calabria Hospital, Negrar 
      (Verona) - Italy.
FAU - Ricchetti, Francesco
AU  - Ricchetti F
AD  - Department of Radiation Oncology, Sacro Cuore Don Calabria Hospital, Negrar 
      (Verona) - Italy.
FAU - Alongi, Filippo
AU  - Alongi F
AD  - Department of Radiation Oncology, Sacro Cuore Don Calabria Hospital, Negrar 
      (Verona) - Italy.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
DEP - 20161111
PL  - United States
TA  - Tumori
JT  - Tumori
JID - 0111356
SB  - IM
MH  - Adult
MH  - Breast Neoplasms/pathology/*radiotherapy
MH  - Combined Modality Therapy
MH  - Dose Fractionation, Radiation
MH  - Female
MH  - Humans
MH  - Lymphatic Metastasis
MH  - Neoplasm Staging
MH  - Radiotherapy Dosage
MH  - Radiotherapy Planning, Computer-Assisted
MH  - Radiotherapy, Adjuvant
MH  - *Radiotherapy, Intensity-Modulated/methods
EDAT- 2016/10/30 06:00
MHDA- 2017/02/07 06:00
CRDT- 2016/10/08 06:00
PHST- 2016/08/16 00:00 [accepted]
PHST- 2016/10/30 06:00 [pubmed]
PHST- 2017/02/07 06:00 [medline]
PHST- 2016/10/08 06:00 [entrez]
AID - B295489C-37AA-4F8C-9614-317D2FB3B83F [pii]
AID - 10.5301/tj.5000568 [doi]
PST - epublish
SO  - Tumori. 2016 Nov 11;102(Suppl. 2). doi: 10.5301/tj.5000568.