PMID- 27718079 OWN - NLM STAT- MEDLINE DCOM- 20180102 LR - 20200330 IS - 1432-1084 (Electronic) IS - 0938-7994 (Linking) VI - 27 IP - 6 DP - 2017 Jun TI - Breast dose reduction for chest CT by modifying the scanning parameters based on the pre-scan size-specific dose estimate (SSDE). PG - 2267-2274 LID - 10.1007/s00330-016-4618-6 [doi] AB - OBJECTIVE: To investigate the usefulness of modifying scanning parameters based on the size-specific dose estimate (SSDE) for a breast-dose reduction for chest CT. MATERIALS AND METHODS: We scanned 26 women with a fixed volume CT dose index (CTDI(vol)) (15 mGy) and another 26 with a fixed SSDE (15 mGy) protocol (protocol 1 and 2, respectively). In protocol 2, tube current was calculated based on the patient habitus obtained on scout images. We compared the mean breast dose and the inter-patient breast dose variability and performed linear regression analysis of the breast dose and the body mass index (BMI) of the two protocols. RESULTS: The mean breast dose was about 35 % lower under protocol 2 than protocol 1 (10.9 mGy vs. 16.8 mGy, p < 0.01). The inter-patient breast dose variability was significantly lower under protocol 2 than 1 (1.2 mGy vs. 2.5 mGy, p < 0.01). We observed a moderate negative correlation between the breast dose and the BMI under protocol 1 (r = 0.43, p < 0.01); there was no significant correlation (r = 0.06, p = 0.35) under protocol 2. CONCLUSION: The SSDE-based protocol achieved a reduction in breast dose and in inter-patient breast dose variability. KEY POINTS: * CT scan parameters can be modified based on the pre-scan SSDE. * The pre-scan SSDE is useful for a breast dose reduction. * The fixed SSDE protocol reduced individual variations in the breast dose. FAU - Kidoh, Masafumi AU - Kidoh M AD - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, 860-8556, Japan. masafkidoh@yahoo.co.jp. FAU - Utsunomiya, Daisuke AU - Utsunomiya D AD - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, 860-8556, Japan. FAU - Oda, Seitaro AU - Oda S AD - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, 860-8556, Japan. FAU - Nakaura, Takeshi AU - Nakaura T AD - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, 860-8556, Japan. FAU - Funama, Yoshinori AU - Funama Y AD - Department of Medical Physics, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, 860-8556, Japan. FAU - Yuki, Hideaki AU - Yuki H AD - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, 860-8556, Japan. FAU - Hirata, Kenichiro AU - Hirata K AD - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, 860-8556, Japan. FAU - Namimoto, Tomohiro AU - Namimoto T AD - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, 860-8556, Japan. FAU - Sakabe, Daisuke AU - Sakabe D AD - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, 860-8556, Japan. FAU - Hatemura, Masahiro AU - Hatemura M AD - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, 860-8556, Japan. FAU - Yamashita, Yasuyuki AU - Yamashita Y AD - Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, 860-8556, Japan. LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20161007 PL - Germany TA - Eur Radiol JT - European radiology JID - 9114774 SB - IM MH - Body Mass Index MH - Breast/*radiation effects MH - Female MH - Humans MH - Linear Models MH - Middle Aged MH - Prospective Studies MH - Radiation Dosage MH - Radiography, Thoracic/*radiation effects MH - Radionuclide Imaging MH - Tomography, X-Ray Computed/methods OTO - NOTNLM OT - Breast radiation dose OT - CTDIvol OT - Chest CT OT - MOSFET OT - SSDE EDAT- 2016/10/09 06:00 MHDA- 2018/01/03 06:00 CRDT- 2016/10/09 06:00 PHST- 2016/05/25 00:00 [received] PHST- 2016/09/22 00:00 [accepted] PHST- 2016/09/12 00:00 [revised] PHST- 2016/10/09 06:00 [pubmed] PHST- 2018/01/03 06:00 [medline] PHST- 2016/10/09 06:00 [entrez] AID - 10.1007/s00330-016-4618-6 [pii] AID - 10.1007/s00330-016-4618-6 [doi] PST - ppublish SO - Eur Radiol. 2017 Jun;27(6):2267-2274. doi: 10.1007/s00330-016-4618-6. Epub 2016 Oct 7.