PMID- 27718479
OWN - NLM
STAT- MEDLINE
DCOM- 20171124
LR  - 20171128
IS  - 1862-278X (Electronic)
IS  - 0013-5585 (Linking)
VI  - 62
IP  - 4
DP  - 2017 Aug 28
TI  - Fabrication of multifunctional CaP-TC composite coatings and the corrosion 
      protection they provide for magnesium alloys.
PG  - 375-381
LID - 10.1515/bmt-2015-0247 [doi]
AB  - Two major problems with magnesium (Mg) alloy biomaterials are the poor corrosion 
      resistance and infection associated with implantation. In this study, a novel 
      calcium phosphate (CaP)/tetracycline (TC) composite coating for Mg implants that 
      can both improve the corrosion resistance of Mg and release a drug in a durable 
      way is reported. Scanning electron microscope (SEM) images showed that TC 
      additives make the CaP coating more compact and uniform. Electrochemical tests 
      indicated CaP/TC coatings can provide excellent corrosion protection for Mg alloy 
      substrates. Besides, TC additives can also provide effective prevention of bone 
      infection and inflammation due to its broad-spectrum antibacterial properties. 
      The one-step hydrothermal process reported here greatly simplified the multi-step 
      fabrication of smart coatings reported previously.
FAU - Tan, Cui
AU  - Tan C
AD  - .
FAU - Zhang, Xiaoxu
AU  - Zhang X
AD  - .
FAU - Li, Qing
AU  - Li Q
AD  - .
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Biomed Tech (Berl)
JT  - Biomedizinische Technik. Biomedical engineering
JID - 1262533
RN  - 0 (Alloys)
RN  - 0 (Calcium Phosphates)
RN  - 0 (Coated Materials, Biocompatible)
RN  - 97Z1WI3NDX (calcium phosphate)
RN  - I38ZP9992A (Magnesium)
SB  - IM
MH  - Alloys/*chemistry
MH  - Calcium Phosphates/*chemistry
MH  - Coated Materials, Biocompatible/*chemistry
MH  - Corrosion
MH  - Humans
MH  - Magnesium/*chemistry
MH  - Prostheses and Implants/*standards
OTO - NOTNLM
OT  - Mg alloys
OT  - antibacterial
OT  - biomaterials
OT  - corrosion
EDAT- 2016/10/09 06:00
MHDA- 2017/11/29 06:00
CRDT- 2016/10/09 06:00
PHST- 2015/12/30 00:00 [received]
PHST- 2016/08/19 00:00 [accepted]
PHST- 2016/10/09 06:00 [pubmed]
PHST- 2017/11/29 06:00 [medline]
PHST- 2016/10/09 06:00 [entrez]
AID - /j/bmte.ahead-of-print/bmt-2015-0247/bmt-2015-0247.xml [pii]
AID - 10.1515/bmt-2015-0247 [doi]
PST - ppublish
SO  - Biomed Tech (Berl). 2017 Aug 28;62(4):375-381. doi: 10.1515/bmt-2015-0247.