PMID- 27721242
OWN - NLM
STAT- MEDLINE
DCOM- 20170316
LR  - 20170316
IS  - 1998-4138 (Electronic)
IS  - 1998-4138 (Linking)
VI  - 12
IP  - Supplement
DP  - 2016 Oct
TI  - Laparoscopic jejunoileal side-to-side anastomosis for the treatment of type 2 
      diabetes mellitus in Chinese patients with a body mass index of 24-32 kg/m(2).
PG  - 5-10
LID - 10.4103/0973-1482.191618 [doi]
AB  - OBJECTIVE: Laparoscopic jejunoileal side-to-side anastomosis (LJISSA) is an 
      upcoming procedure that offers good metabolic improvement without causing 
      significant malabsorption. The objective of this study was to evaluate the 
      results of this novel procedure for the control of type 2 diabetes mellitus 
      (T2DM) in patients with a body mass index (BMI) of 24-32 kg/m 2. MATERIALS AND 
      METHODS: Fifty-seven patients with T2DM who underwent LJISSA between February 
      2010 and May 2013 were recruited in this study. Data collected included fasting 
      blood glucose (FBG), 2 h postprandial blood glucose (2 h PBG), 1 h postprandial C 
      peptide (1 h C-P), and glycosylated hemoglobin (HbA1c). RESULTS: Postoperatively, 
      glycemic parameters (FBG and 2 h PBG, HbA1c and 1 h C-P) improved in all 57 
      patients. At 12 months, 34 patients had a remission of diabetes, and the 
      remaining 23 patients showed a significantly decreased requirement for oral 
      hypoglycemic agents. The patients with a BMI of 28-32 kg/m 2 had significant 
      weight loss of between 7.8% and 20% (P < 0.05), whereas weight loss was not 
      significant in those with a BMI of 24-28 kg/m 2. The group achieving remission 
      had a higher BMI (28-32 kg/m 2), shorter duration of diabetes (<10 years), and 
      higher stimulated C-P (>4 ng/mL). These three factors may be the predictors of 
      diabetes resolution at 12 months. CONCLUSION: LJISSA seems to be a promising 
      procedure for the control of T2DM. A multicenter study with a larger number of 
      patients and a longer follow-up period is needed to substantiate our preliminary 
      findings.
FAU - Li, Jin
AU  - Li J
AD  - Department of Oncology Surgery, Xuzhou Central Hospital, Affiliated Hospital of 
      Medical College of Southeast University, Xuzhou 221009, People's Republic of 
      China.
FAU - Xie, Guangwei
AU  - Xie G
AD  - Department of Oncology Surgery, Xuzhou Central Hospital, Affiliated Hospital of 
      Medical College of Southeast University, Xuzhou 221009, People's Republic of 
      China.
FAU - Tian, Qingzhong
AU  - Tian Q
AD  - Department of Oncology Surgery, Xuzhou Central Hospital, Affiliated Hospital of 
      Medical College of Southeast University, Xuzhou 221009, People's Republic of 
      China.
FAU - Hu, Yuanchao
AU  - Hu Y
AD  - Department of Oncology Surgery, Xuzhou Central Hospital, Affiliated Hospital of 
      Medical College of Southeast University, Xuzhou 221009, People's Republic of 
      China.
FAU - Meng, Qingliang
AU  - Meng Q
AD  - Department of Oncology Surgery, Xuzhou Central Hospital, Affiliated Hospital of 
      Medical College of Southeast University, Xuzhou 221009, People's Republic of 
      China.
FAU - Zhang, Minkang
AU  - Zhang M
AD  - Department of Oncology Surgery, Xuzhou Central Hospital, Affiliated Hospital of 
      Medical College of Southeast University, Xuzhou 221009, People's Republic of 
      China.
LA  - eng
PT  - Journal Article
PL  - India
TA  - J Cancer Res Ther
JT  - Journal of cancer research and therapeutics
JID - 101249598
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - *Anastomosis, Surgical
MH  - *Body Mass Index
MH  - Body Weight
MH  - Diabetes Mellitus, Type 2/*complications/*surgery
MH  - Energy Metabolism
MH  - Female
MH  - Humans
MH  - Jejunum/*surgery
MH  - *Laparoscopy/methods
MH  - Male
MH  - Middle Aged
MH  - Obesity/*complications
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2016/10/11 06:00
MHDA- 2017/03/17 06:00
CRDT- 2016/10/11 06:00
PHST- 2016/10/11 06:00 [entrez]
PHST- 2016/10/11 06:00 [pubmed]
PHST- 2017/03/17 06:00 [medline]
AID - JCanResTher_2016_12_5_5_191618 [pii]
AID - 10.4103/0973-1482.191618 [doi]
PST - ppublish
SO  - J Cancer Res Ther. 2016 Oct;12(Supplement):5-10. doi: 10.4103/0973-1482.191618.