PMID- 2772367
OWN - NLM
STAT- MEDLINE
DCOM- 19890928
LR  - 20140728
IS  - 0300-8932 (Print)
IS  - 0300-8932 (Linking)
VI  - 42
IP  - 5
DP  - 1989 May
TI  - [Cardiovascular pathology in Marfan syndrome. Study of 11 children using 
      two-dimensional echocardiography].
PG  - 318-21
AB  - From 1983 to 1987 we have studied by two-dimensional echocardiography 11 
      pediatric patients with Marfan's syndrome. All of them presented cardiovascular 
      lesions localized mainly in the aortic and mitral valves and in the ascending 
      aorta. Nine patients had a dilated aortic ring in both transversal and 
      longitudinal diameters 2.03 and 2.29 cm/m2 of body surface (bs), respectively. 
      The average value of the aortic valvular area was 4.71 cm2/m2 bs. The 9 patients 
      presented also dilatation of the ascending aorta (2.01 cm/cm2 bs). There was 
      thickening of the mitral valve in 5 cases and a prolapse was present in 8 (73%). 
      In 4 cases the prolapse was localized in anterior leaflet valve in 2 in the 
      posterior and in 2 in both. The maximal mitral valve diastolic area was 3.25 
      cm2/m2 bs. None of them has needed during follow up valvular replacement. 
      Considering the importance of this cardiovascular disease and knowing its 
      unpredictable evolution we recommend, in the absence of valvular insufficiency, 
      and annual echocardiographic reevaluation, and more often if valvular 
      insufficiency is already present. IN CONCLUSION: two-dimensional 
      echocardiographic is useful and necessary for the diagnosis and follow up of 
      patients with Marfan's syndrome.
FAU - Modesto, C
AU  - Modesto C
FAU - Cabrera, A
AU  - Cabrera A
FAU - Pastor, E
AU  - Pastor E
FAU - Hernaez, E
AU  - Hernaez E
FAU - Sarrionandia, M J
AU  - Sarrionandia MJ
FAU - Zubeldia, J
AU  - Zubeldia J
FAU - Galdeano, J M
AU  - Galdeano JM
FAU - Cabrera, J A
AU  - Cabrera JA
LA  - spa
PT  - English Abstract
PT  - Journal Article
TT  - Patologia cardiovascular en el sindrome de Marfan. Estudio de 11 ninos con 
      ecocardiografia bidimensional.
PL  - Spain
TA  - Rev Esp Cardiol
JT  - Revista espanola de cardiologia
JID - 0404277
SB  - IM
MH  - Adolescent
MH  - Aorta/*pathology
MH  - Aortic Valve/*pathology
MH  - Child
MH  - Child, Preschool
MH  - Echocardiography
MH  - Female
MH  - Heart Atria/pathology
MH  - Humans
MH  - Male
MH  - Marfan Syndrome/*pathology
MH  - Mitral Valve/*pathology
EDAT- 1989/05/01 00:00
MHDA- 1989/05/01 00:01
CRDT- 1989/05/01 00:00
PHST- 1989/05/01 00:00 [pubmed]
PHST- 1989/05/01 00:01 [medline]
PHST- 1989/05/01 00:00 [entrez]
PST - ppublish
SO  - Rev Esp Cardiol. 1989 May;42(5):318-21.