PMID- 27729965
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 2032-0418 (Print)
IS  - 2032-0418 (Linking)
VI  - 7
IP  - 4
DP  - 2015 Dec 28
TI  - Reproducibility of 3-Dimensional Ultrasound Measurements of Placental Volume at 
      Gestational Ages 11 - 14 Weeks.
PG  - 203-209
AB  - OBJECTIVE: To evaluate the reproducibility of placental volume using 
      three-dimensional ultrasound. METHODS: The VOCAL (Virtual Organ Computer-aided 
      AnaLysis) technique involves rotating an image of an object along an established 
      axis using predefined angles. This provides a number of sections to measure 
      manually, resulting in the object being displayed with an estimated placental 
      volume. Four predefined angles 30 degrees , 15 degrees , 9 degrees , and 6 degrees , creating 6, 12, 20 and 30 
      sections, respectively. Measurements of placenta volumes in 21 women with 
      singleton pregnancies were performed at gestational age 11-14 weeks by a single 
      consultant in Foetal Medicine and later processed by two observers. The 
      intraobserver reproducibility between all four angles was calculated as the mean 
      Coefficient of Variation. Interobserver reproducibility was assessed by 
      Interclass Correlation Coefficient (ICC), Limits of Agreement (LOA) and 
      illustrated in Bland-Altman plots. RESULTS: There was no significant difference 
      in intraobserver variability between the four angles, p = 0.19, but a trend 
      towards a lower coefficient of variation with the smallest angle was observed. A 
      high intraobserver reproducibility was found using the 6 degrees  angle (ICC = 0.918 
      (0.812 - 0.966) and 0.983 (0.960- 0.993), LOA = [-22.9- 22.5] and [-14.3 - 
      12.1]), but interobserver reproducibility showed a wide range of agreement (LOA = 
      [-50.5- 34.8]), particularly in cases with u-shaped placentas. CONCLUSION: The 
      low interobserver reproducibility of VOCAL measurements of placentae requires 
      significant differences between normal and abnormal cases if the technique should 
      be implemented for clinical use.
FAU - Larsen, M L
AU  - Larsen ML
AD  - Department of Obstetrics and Gynaecology, University Hospital Hvidovre, 
      University of Copenhagen, Denmark.
FAU - Naver, K V
AU  - Naver KV
AD  - Department of Obstetrics and Gynaecology, University Hospital Hvidovre, 
      University of Copenhagen, Denmark.
FAU - Kjaer, M M
AU  - Kjaer MM
AD  - Department of Obstetrics and Gynaecology, University Hospital Hvidovre, 
      University of Copenhagen, Denmark.
FAU - Jorgensen, F S
AU  - Jorgensen FS
AD  - Department of Obstetrics and Gynaecology, University Hospital Hvidovre, 
      University of Copenhagen, Denmark.
FAU - Nilas, L
AU  - Nilas L
AD  - Department of Obstetrics and Gynaecology, University Hospital Hvidovre, 
      University of Copenhagen, Denmark.
LA  - eng
PT  - Journal Article
PL  - Belgium
TA  - Facts Views Vis Obgyn
JT  - Facts, views & vision in ObGyn
JID - 101578773
PMC - PMC5058409
OTO - NOTNLM
OT  - Placental volume
OT  - VOCAL
OT  - reproducibility
OT  - three-dimensional ultrasound
OT  - variability
OT  - virtual Organ Computeraided AnaLysis
EDAT- 2016/10/13 06:00
MHDA- 2016/10/13 06:01
PMCR- 2015/12/28
CRDT- 2016/10/13 06:00
PHST- 2016/10/13 06:00 [entrez]
PHST- 2016/10/13 06:00 [pubmed]
PHST- 2016/10/13 06:01 [medline]
PHST- 2015/12/28 00:00 [pmc-release]
PST - ppublish
SO  - Facts Views Vis Obgyn. 2015 Dec 28;7(4):203-209.