PMID- 27742755 OWN - NLM STAT- MEDLINE DCOM- 20180806 LR - 20220409 IS - 2048-8734 (Electronic) IS - 2048-8726 (Linking) VI - 7 IP - 1 DP - 2018 Feb TI - Percutaneous balloon atrial septostomy on top of venoarterial extracorporeal membrane oxygenation results in safe and effective left heart decompression. PG - 70-79 LID - 10.1177/2048872616675485 [doi] AB - BACKGROUND: Transcatheter techniques are emerging for left atrial (LA) decompression under venoarterial extracorporeal membrane oxygenation (VA-ECMO). We aimed to assess whether balloon atrioseptostomy (BAS) is a safe and efficient strategy. METHODS: All patients who underwent percutaneous static BAS under VA-ECMO at four tertiary institutions were retrospectively reviewed. RESULTS: From 2000 to 2014, BAS was performed in 64 patients (32 adults and 32 children). Indications for ECMO support included acute myocarditis (31.3%) and non-myocarditis cardiac disease, mostly end-stage dilated cardiomyopathy (32.8%). BAS was required because of pulmonary oedema/haemorrhage and left ventricular (LV) distension. The mean balloon diameter was 21.8 +/- 8.4mm. Adequate LA decompression was achieved in all patients. Mean LA pressure fell from 24.2 +/- 6.9 mmHg to 7.8 +/- 2.6 mmHg ( p < 0.001). The left-to-right atrial pressure gradient fell from 17.2 +/- 7.1 mmHg to 0.09 +/- 0.5 mmHg ( p < 0.001). Echocardiography showed an unrestrictive left-to-right atrial shunting in all patients. Improvement of day 1 chest X-ray was observed in 76.6% of patients, clinical status in 98.4% of patients and pulmonary haemorrhage in 14 out of 14 patients. Complications occurred in 9.4% of patients, representing pericardial effusion, fast atrial fibrillation, ventricular fibrillation requiring defibrillation, transient complete heart block and femoral venous dissection requiring covered stent placement. In the 37 (57.8%) patients who were successfully decannulated, the median ECMO duration was 9 (range: 4-24) days. After a median follow-up of 12.3 (range: 0.1-142) months, 35.9% patients died, 17.2% received a LV assist device as a bridge to transplantation, 31.2% were transplanted and 56.2% were home discharged and alive. CONCLUSIONS: Percutaneous BAS may be a safe and efficient strategy for discharging the LA in both adults and children supported by VA-ECMO. FAU - Baruteau, Alban-Elouen AU - Baruteau AE AD - 1 Department of Paediatric Cardiology, Royal Brompton Hospital and Harefield NHS Foundation Trust, Imperial College London, London, UK. AD - 2 Cardiology Clinical Academic Group, Cardiovascular and Cell Sciences Research Institute, St George's University of London, London, UK. AD - 3 IHU LIRYC, Electrophysiology and Heart Modeling Institute, INSERM U1045, Bordeaux, France. FAU - Barnetche, Thomas AU - Barnetche T AD - 4 Department of Rheumatology, University Hospital Pellegrin, Bordeaux, France. FAU - Morin, Luc AU - Morin L AD - 5 Department of Pediatric Intensive Care, Paris South University Hospitals, Assistance Publique Hopitaux de Paris, Le Kremlin-Bicetre, France. FAU - Jalal, Zakaria AU - Jalal Z AD - 3 IHU LIRYC, Electrophysiology and Heart Modeling Institute, INSERM U1045, Bordeaux, France. AD - 6 Department of Pediatric Cardiology, Haut-Leveque Hospital, Bordeaux University, Bordeaux, France. FAU - Boscamp, Nicholas S AU - Boscamp NS AD - 7 Division of Pediatric Cardiology, Morgan Stanley Children's Hospital, New York Presbyterian Hospital, Columbia University Medical Center, New York, NY, USA. FAU - Le Bret, Emmanuel AU - Le Bret E AD - 8 Department of Pediatric Cardiac Surgery, Marie-Lannelongue Hospital, Paris, France. FAU - Thambo, Jean-Benoit AU - Thambo JB AD - 3 IHU LIRYC, Electrophysiology and Heart Modeling Institute, INSERM U1045, Bordeaux, France. AD - 6 Department of Pediatric Cardiology, Haut-Leveque Hospital, Bordeaux University, Bordeaux, France. FAU - Vincent, Julie A AU - Vincent JA AD - 7 Division of Pediatric Cardiology, Morgan Stanley Children's Hospital, New York Presbyterian Hospital, Columbia University Medical Center, New York, NY, USA. FAU - Fraisse, Alain AU - Fraisse A AD - 1 Department of Paediatric Cardiology, Royal Brompton Hospital and Harefield NHS Foundation Trust, Imperial College London, London, UK. FAU - Torres, Alejandro J AU - Torres AJ AD - 7 Division of Pediatric Cardiology, Morgan Stanley Children's Hospital, New York Presbyterian Hospital, Columbia University Medical Center, New York, NY, USA. LA - eng PT - Journal Article PT - Multicenter Study DEP - 20161014 PL - England TA - Eur Heart J Acute Cardiovasc Care JT - European heart journal. Acute cardiovascular care JID - 101591369 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Cardiac Catheterization/*methods MH - Cardiac Surgical Procedures/*methods MH - Child MH - Child, Preschool MH - Decompression, Surgical/*methods MH - Echocardiography MH - Extracorporeal Membrane Oxygenation/*methods MH - Female MH - Follow-Up Studies MH - Heart Atria/diagnostic imaging/*surgery MH - Heart Diseases/diagnosis/*surgery MH - Heart Septum/diagnostic imaging/*surgery MH - Humans MH - Infant MH - Male MH - Middle Aged MH - Retrospective Studies MH - Time Factors MH - Treatment Outcome MH - Young Adult OTO - NOTNLM OT - ECMO support OT - cardiogenic shock OT - haemodynamics OT - outcomes OT - pulmonary oedema OT - transcatheter techniques EDAT- 2016/10/16 06:00 MHDA- 2018/08/07 06:00 CRDT- 2016/10/16 06:00 PHST- 2016/10/16 06:00 [pubmed] PHST- 2018/08/07 06:00 [medline] PHST- 2016/10/16 06:00 [entrez] AID - 2048872616675485 [pii] AID - 10.1177/2048872616675485 [doi] PST - ppublish SO - Eur Heart J Acute Cardiovasc Care. 2018 Feb;7(1):70-79. doi: 10.1177/2048872616675485. Epub 2016 Oct 14.