PMID- 27747288
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 2364-3722 (Print)
IS  - 2196-9736 (Electronic)
IS  - 2196-9736 (Linking)
VI  - 4
IP  - 10
DP  - 2016 Oct
TI  - Clinical outcomes of endoscopic ultrasound-guided ethanol injection for 
      hepatocellular carcinoma in the caudate lobe.
PG  - E1111-E1115
AB  - Background and study aims: Accurately puncturing hepatocellular carcinomas (HCC) 
      that arise from the caudate lobe is generally considered to be technically 
      difficult. We conducted a retrospective study to evaluate the feasibility and 
      safety (the therapeutic outcomes and adverse events) of endoscopic ultrasound 
      (EUS)-guided ethanol injection as a novel treatment for HCC in the caudate lobe. 
      Patients and methods: Twelve patients with early-stage HCC of the caudate lobe 
      that were treated with EUS-guided ethanol injection at two tertiary referral 
      centers were reviewed retrospectively. To evaluate the therapeutic effect of the 
      treatment, a local control curve and an overall survival curve were constructed 
      using the Kaplan-Meier method. Results: The mean follow-up duration was 31.0 
      months. The 1-year local control rate was 80.2 %, and recurrent lesions developed 
      in 2 cases (after 3 and 9 months, respectively). The overall survival rate was 
      91.7 %, 75.0 %, and 53.3 % at 1, 2, and 3 years, respectively. Concerning 
      procedure-related adverse events (AEs), 2 patients suffered episodes of fever 
      lasting a few days; however, no serious AEs occurred. Conclusions: EUS-guided 
      ethanol injection could be a useful treatment for early-stage HCC in the caudate 
      lobe because of its simplicity and reduced invasiveness.
FAU - Nakaji, So
AU  - Nakaji S
AD  - Department of Gastroenterology, Kameda Medical Center.
FAU - Hirata, Nobuto
AU  - Hirata N
AD  - Department of Gastroenterology, Kameda Medical Center.
FAU - Mikata, Rintaro
AU  - Mikata R
AD  - Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba 
      University.
FAU - Kobayashi, Masayoshi
AU  - Kobayashi M
AD  - Department of Gastroenterology, Kameda Medical Center.
FAU - Shiratori, Toshiyasu
AU  - Shiratori T
AD  - Department of Gastroenterology, Kameda Medical Center.
FAU - Ogasawara, Sadahisa
AU  - Ogasawara S
AD  - Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba 
      University.
FAU - Ooka, Yoshihiko
AU  - Ooka Y
AD  - Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba 
      University.
FAU - Tsuyuguchi, Toshio
AU  - Tsuyuguchi T
AD  - Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba 
      University.
FAU - Yamaguchi, Taketo
AU  - Yamaguchi T
AD  - Department of Gastroenterology, Chiba Cancer Center.
FAU - Yokosuka, Osamu
AU  - Yokosuka O
AD  - Department of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba 
      University.
LA  - eng
PT  - Journal Article
DEP - 20160930
PL  - Germany
TA  - Endosc Int Open
JT  - Endoscopy international open
JID - 101639919
PMC - PMC5063731
COIS- Competing interests: None
EDAT- 2016/10/18 06:00
MHDA- 2016/10/18 06:01
PMCR- 2016/10/01
CRDT- 2016/10/18 06:00
PHST- 2016/04/06 00:00 [received]
PHST- 2016/08/19 00:00 [accepted]
PHST- 2016/10/18 06:00 [entrez]
PHST- 2016/10/18 06:00 [pubmed]
PHST- 2016/10/18 06:01 [medline]
PHST- 2016/10/01 00:00 [pmc-release]
AID - 10.1055/s-0042-116146 [doi]
PST - ppublish
SO  - Endosc Int Open. 2016 Oct;4(10):E1111-E1115. doi: 10.1055/s-0042-116146. Epub 
      2016 Sep 30.