PMID- 27755806 OWN - NLM STAT- MEDLINE DCOM- 20170317 LR - 20181113 IS - 1759-7714 (Electronic) IS - 1759-7706 (Print) IS - 1759-7706 (Linking) VI - 7 IP - 6 DP - 2016 Nov TI - Diagnosis of a rare primary pulmonary synovial sarcoma with endobronchial ultrasound-guided transbronchial needle aspiration. PG - 684-688 LID - 10.1111/1759-7714.12385 [doi] AB - Primary pulmonary synovial sarcoma (PPSS) is a rare disease. Diagnosis is made postoperatively following resection of the tumor. We describe the case of a 39-year-old non-smoking woman whose chest imaging revealed a heterogeneous mass (5.4 cm x 4.6 cm), with soft tissue density in the right upper lobe and pleural effusion in the right hemithorax. The tumor was enhanced on a computed tomography scan, in which enlargement of the mediastinal lymph nodes compressing the adjacent superior vena cava was observed. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) was then performed, which demonstrated PPSS, subsequently confirmed by immunohistochemistry and the detection of a SYT-SSX fusion gene. We believe that a diagnostic approach of EBUS-TBNA for lung sarcoma would provide helpful information to clinicians. CI - (c) 2016 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd. FAU - Wang, Cai-Hua AU - Wang CH AD - Department of Respiratory Medicine, The First Affiliated Hospital of Soochow University, Suzhou, China. FAU - Xu, Chuan-Cai AU - Xu CC AD - Department of Respiratory Medicine, The First Affiliated Hospital of Soochow University, Suzhou, China. FAU - Jiang, Jun-Hong AU - Jiang JH AD - Department of Respiratory Medicine, The First Affiliated Hospital of Soochow University, Suzhou, China. jiangjunhong@263.net. FAU - Chen, Yan-Bin AU - Chen YB AD - Department of Respiratory Medicine, The First Affiliated Hospital of Soochow University, Suzhou, China. FAU - Zhan, Sheng-Hua AU - Zhan SH AD - Department of Pathology, The First Affiliated Hospital of Soochow University, Suzhou, China. LA - eng PT - Case Reports DEP - 20160910 PL - Singapore TA - Thorac Cancer JT - Thoracic cancer JID - 101531441 RN - 0 (Oncogene Proteins, Fusion) RN - 0 (SYT-SSX fusion protein) SB - IM MH - Adult MH - Endoscopic Ultrasound-Guided Fine Needle Aspiration/*methods MH - Female MH - Humans MH - Image-Guided Biopsy MH - Lung Neoplasms/*diagnosis/genetics MH - Oncogene Proteins, Fusion/genetics MH - Sarcoma, Synovial/*diagnosis/genetics PMC - PMC5093178 OTO - NOTNLM OT - Diagnosis OT - SYT-SSX fusion gene OT - endobronchial ultrasound-guided transbronchial needle aspiration OT - primary pulmonary synovial sarcoma EDAT- 2016/11/04 06:00 MHDA- 2017/03/18 06:00 PMCR- 2016/11/01 CRDT- 2016/11/04 06:00 PHST- 2016/05/04 00:00 [received] PHST- 2016/07/20 00:00 [revised] PHST- 2016/07/21 00:00 [accepted] PHST- 2016/11/04 06:00 [pubmed] PHST- 2017/03/18 06:00 [medline] PHST- 2016/11/04 06:00 [entrez] PHST- 2016/11/01 00:00 [pmc-release] AID - TCA12385 [pii] AID - 10.1111/1759-7714.12385 [doi] PST - ppublish SO - Thorac Cancer. 2016 Nov;7(6):684-688. doi: 10.1111/1759-7714.12385. Epub 2016 Sep 10.