PMID- 27759642
OWN - NLM
STAT- MEDLINE
DCOM- 20170210
LR  - 20210109
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 95
IP  - 42
DP  - 2016 Oct
TI  - Sialodochitis fibrinosa (kussmaul disease) report of 3 cases and literature 
      review.
PG  - e5132
LID - 10.1097/MD.0000000000005132 [doi]
LID - e5132
AB  - BACKGROUND: Sialodochitis fibrinosa is a rare disease which is characterized by 
      recurring episodes of pain and swelling of the salivary glands due to the 
      formation of mucofibrinous plugs. Analytic studies ascertain elevated levels of 
      eosinophils and immunoglobulin E (IgE). Imaging studies such as magnetic 
      resonance imaging (MRI) and sialography reveal dilation of the main salivary duct 
      (duct ectasia). Treatment is initially supportive, consisting of compressive 
      massages, and use of antihistamines and/or corticosteroids. MATERIAL AND METHODS: 
      In the following, 3 cases of sialodochitis fibrinosa are presented which were 
      diagnosed in a third level hospital during the period of 2008 and 2016, as well 
      as a literature review of all cases reported to our knowledge. RESULTS: Of the 41 
      cases found, including the 3 of this article, 66% were women with an average age 
      of 45 years old. However, 75% of reported cases were of Japanese heritage. 
      Involvement of the parotid glands was more frequent than the submandibular 
      glands. In more than half of all cases treatment with compressive massages, 
      antihistamines and/or corticosteroids was effective. CONCLUSION: Clinicians 
      should consider sialodochitis fibrinosa as a diagnostic possibility when 
      presented with cases of recurring parotid and submandibular gland tumescence.
FAU - Flores Robles, Bryan Josue
AU  - Flores Robles BJ
AD  - Rheumatology Division Radiodiagnostic Division, Puerta de Hierro Hospital, Madrid 
      Neurology Division, Lozano Blesa Hospital, Zaragoza, Spain Independence 
      Polyclinic, Belize Haematology Division Allergology Division Anatomical Pathology 
      Division, Puerta de Hierro Hospital, Madrid, Spain.
FAU - Brea Alvarez, Beatriz
AU  - Brea Alvarez B
FAU - Sanabria Sanchinel, Abel Alejandro
AU  - Sanabria Sanchinel AA
FAU - Andrus, Robert Francis
AU  - Andrus RF
FAU - Espinosa Malpartida, Maria
AU  - Espinosa Malpartida M
FAU - Ramos Giraldez, Consuelo
AU  - Ramos Giraldez C
FAU - Lerma Verdejo, Ana
AU  - Lerma Verdejo A
FAU - Merino Argumanez, Carolina
AU  - Merino Argumanez C
FAU - Perez Pimiento, Jose Antonio
AU  - Perez Pimiento JA
FAU - Bellas Menendez, Camen
AU  - Bellas Menendez C
FAU - Villa Alcazar, Luis Fernando
AU  - Villa Alcazar LF
FAU - Andreu Sanchez, Jose Luis
AU  - Andreu Sanchez JL
FAU - Jimenez Palop, Mercedes
AU  - Jimenez Palop M
FAU - Godoy Tundidor, Hildegarda
AU  - Godoy Tundidor H
FAU - Campos Esteban, Jose
AU  - Campos Esteban J
FAU - Sanz Sanz, Jesus
AU  - Sanz Sanz J
FAU - Barbadillo Mateos, Carmen
AU  - Barbadillo Mateos C
FAU - Isasi Zaragoza, Carlos Maria
AU  - Isasi Zaragoza CM
FAU - Mulero Mendoza, Juan Bartolome
AU  - Mulero Mendoza JB
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - IM
MH  - Adult
MH  - Diagnosis, Differential
MH  - Female
MH  - Fibrosis/diagnosis
MH  - Humans
MH  - Magnetic Resonance Imaging/*methods
MH  - Middle Aged
MH  - Recurrence
MH  - Sialography
MH  - Submandibular Gland/*diagnostic imaging
MH  - Submandibular Gland Diseases/*diagnosis
PMC - PMC5079326
COIS- The authors have no funding and conflicts of interest to disclose.
EDAT- 2016/10/21 06:00
MHDA- 2017/02/12 06:00
PMCR- 2016/10/21
CRDT- 2016/10/21 06:00
PHST- 2016/10/21 06:00 [pubmed]
PHST- 2017/02/12 06:00 [medline]
PHST- 2016/10/21 06:00 [entrez]
PHST- 2016/10/21 00:00 [pmc-release]
AID - 00005792-201610180-00025 [pii]
AID - 10.1097/MD.0000000000005132 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2016 Oct;95(42):e5132. doi: 10.1097/MD.0000000000005132.