PMID- 27759975
OWN - NLM
STAT- MEDLINE
DCOM- 20171016
LR  - 20181023
IS  - 1699-5198 (Electronic)
IS  - 0212-1611 (Linking)
VI  - 33
IP  - 5
DP  - 2016 Sep 20
TI  - Body mass index cutoff point estimation as obesity diagnostic criteria in Down 
      syndrome adolescents.
PG  - 571
LID - 10.20960/nh.571 [doi]
AB  - INTRODUCTION: Adolescents with Down syndrome (DS) show high rate of overweight 
      and tend to accumulate high amount of fat compared to the same people without the 
      syndrome. OBJECTIVE: To estimate the cutoff point of the Body Mass Index (BMI) 
      for the diagnosis of obesity in adolescents with DS according to different 
      references for BMI in relation to the percentage of body fat (%BF) measured by 
      dual-energy X-ray absorptiometry (DXA). METHODS: The sample was composed of 34 
      adolescents with DS (aged: 10 to 17 years old). BMI was evaluated according to 
      the references of the International Obesity Task Force (IOTF), the World Health 
      Organization (WHO) for the general population, and Myrelid et al. and Styles et 
      al. for people with DS. The %BF was assessed by whole body DXA and classified 
      according to National Health And Nutrition Examination Survey (NHANES, 2011). 
      RESULTS: The boys were significantly taller than the girls and this %BF higher 
      than boys. All references who have used BMI to assess obesity was positively 
      associated with %BF measured by DXA in the diagnosis of obesity. Using the ROC 
      curve in relation to %BF by DXA, all references showed high sensitivity, but the 
      z-score of BMI by WHO showed better specificity, with the value of the accuracy 
      of 0.82 for the cutoff point above 2.14. CONCLUSIONS: All the references used for 
      the diagnosis of obesity were associated with %BF measured by DXA, and the cutoff 
      point of z-scores above 2.14 by WHO showed better specificity.
FAU - Samur San-Matin, Juan Eduardo
AU  - Samur San-Matin JE
AD  - Laboratory of Growth and Development. Center for Investigation in Pediatrics 
      (CIPED).. juansamur@gmail.com.
FAU - Goncalves, Ezequiel Moreira
AU  - Goncalves EM
FAU - Bertapelli, Fabio
AU  - Bertapelli F
FAU - Mendes, Roberto Teixeira
AU  - Mendes RT
FAU - Guerra-Junior, Gil
AU  - Guerra-Junior G
LA  - eng
PT  - Journal Article
DEP - 20160920
PL  - Spain
TA  - Nutr Hosp
JT  - Nutricion hospitalaria
JID - 9100365
SB  - IM
MH  - Absorptiometry, Photon
MH  - Adolescent
MH  - Body Composition
MH  - *Body Mass Index
MH  - Child
MH  - Down Syndrome/*complications/epidemiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Obesity/*diagnosis/epidemiology
MH  - Reference Standards
MH  - Sex Factors
OTO - NOTNLM
OT  - Down syndrome. Body mass index. ROC curve. DXA. Anthropometry.
EDAT- 2016/10/21 06:00
MHDA- 2017/10/17 06:00
CRDT- 2016/10/21 06:00
PHST- 2016/09/20 00:00 [received]
PHST- 2016/10/21 06:00 [pubmed]
PHST- 2017/10/17 06:00 [medline]
PHST- 2016/10/21 06:00 [entrez]
AID - 10.20960/nh.571 [doi]
PST - epublish
SO  - Nutr Hosp. 2016 Sep 20;33(5):571. doi: 10.20960/nh.571.