PMID- 2777408 OWN - NLM STAT- MEDLINE DCOM- 19891016 LR - 20221207 IS - 0020-7136 (Print) IS - 0020-7136 (Linking) VI - 44 IP - 3 DP - 1989 Sep 15 TI - A survey of the human T-cell lymphotropic virus type I (HTLV-I) in south-western Colombia. PG - 419-23 AB - To evaluate altitude of birthplace and residence as factors associated with geographic clustering of HTLV-I infection in Colombia, we sampled a total of 670 current residents of the South Pacific coastal lowland and of upland regions (Cali and environs) of the Valle and Cauca Provinces, located at an altitude of 3,100 ft. Among the 255 lowland study subjects, 4.3% had antibody against HTLV-I, compared to 0.9% of the 415 upland study subjects. A hypothesis emerging from this study is that the lower socio-economic status of lowland residents and associated diseases, particularly untreated syphilis and other sexually transmitted diseases, may explain the increased HTLV-I seropositivity rates in this population. FAU - Maloney, E M AU - Maloney EM AD - Environmental Epidemiology Branch, National Cancer Institute, Bethesda, MD 20892. FAU - Ramirez, H AU - Ramirez H FAU - Levin, A AU - Levin A FAU - Blattner, W A AU - Blattner WA LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - Int J Cancer JT - International journal of cancer JID - 0042124 RN - 0 (HTLV-I Antibodies) SB - IM MH - Adult MH - Age Factors MH - Aged MH - Black People MH - Blood Donors MH - Colombia MH - Female MH - HTLV-I Antibodies/*analysis MH - HTLV-I Infections/etiology MH - Humans MH - Male MH - Middle Aged MH - Risk Factors MH - Sexually Transmitted Diseases/complications MH - Socioeconomic Factors EDAT- 1989/09/15 00:00 MHDA- 1989/09/15 00:01 CRDT- 1989/09/15 00:00 PHST- 1989/09/15 00:00 [pubmed] PHST- 1989/09/15 00:01 [medline] PHST- 1989/09/15 00:00 [entrez] AID - 10.1002/ijc.2910440307 [doi] PST - ppublish SO - Int J Cancer. 1989 Sep 15;44(3):419-23. doi: 10.1002/ijc.2910440307.