PMID- 27778267 OWN - NLM STAT- MEDLINE DCOM- 20170413 LR - 20181202 IS - 1614-7499 (Electronic) IS - 0944-1344 (Linking) VI - 24 IP - 2 DP - 2017 Jan TI - Arsenic, cadmium, lead and mercury levels in blood of Finnish adults and their relation to diet, lifestyle habits and sociodemographic variables. PG - 1347-1362 LID - 10.1007/s11356-016-7824-5 [doi] AB - The Northern Finland Birth Cohort program (NFBC) is the epidemiological and longitudinal prospective general population research program, which was established to promote health and wellbeing of the population in northern Finland. The aim of present study, as a part of the NFBC program, was to analyze the blood levels of arsenic (B-As), cadmium (B-Cd), lead (B-Pb), total mercury (B-Hg) and selenium (B-Se); to compare these levels with threshold limits; to study sociodemographic factors; and to correlate these levels with calcium and haemoglobin. The study was comprised of 249 NFBC subjects, of which 123 were female and 126 were male (ages 31.1 +/- 0.3 and 31.1 +/- 0.4, respectively). All participants were asked to complete a questionnaire regarding diet and living habits. The geometric means (+/- SD) of B-As were 0.49 +/- 2.80 mug/l and 0.44 +/- 2.72 mug/l; B-Cd were 0.18 +/- 4.02 mug/l and 0.12 +/- 3.21 mug/l; B-Pb were 17.0 +/- 1.8 mug/l and 9.06 +/- 2.20 mug/l; B-Hg were 2.18 +/- 2.02 mug/l and 1.85 +/- 1.78 mug/l; and B-Se were 106.0 +/- 1.3 and 94.3 +/- 1.3 mug/l in males and females, respectively. Among the subjects in the present analysis, 23 % of males and 17.1 % of females had B-As levels above the ATSDR normal human levels of B-As in unexposed individuals (1.0 mug/l). The B-Pb geometric mean (12.44 mug/l) was approximately one eighth the CDC toxicological cut-off point of 100 mug/l. Twenty-one individuals (8.4 %) exceeded a B-Hg level of 5.8 mug/l. Fifty-eight females (47 %) had a B-Hg higher than 2.0 mug/l, the German Federal Environmental Agency cut-off point for women (18-69 years) who consume fish at least three times/month; therefore, their babies could be at risk of adverse effects during development. FAU - Abass, Khaled AU - Abass K AUID- ORCID: 0000-0002-1843-7644 AD - Research Unit of Biomedicine, University of Oulu, Oulu, Finland. khaled.m.abass@gmail.com. AD - Medical Research Centre Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland. khaled.m.abass@gmail.com. AD - Centre for Arctic Medicine, Thule Institute, University of Oulu, Oulu, Finland. khaled.m.abass@gmail.com. AD - Department of Pesticides, Menoufia University, P.O. Box 32511, Menoufia, Egypt. khaled.m.abass@gmail.com. FAU - Koiranen, Markku AU - Koiranen M AD - Institute of Health Sciences, University of Oulu, Oulu, Finland. FAU - Mazej, Darja AU - Mazej D AD - Department of Environmental Sciences, Jozef Stefan Institute, Ljubljana, Slovenia. FAU - Tratnik, Janja Snoj AU - Tratnik JS AD - Department of Environmental Sciences, Jozef Stefan Institute, Ljubljana, Slovenia. FAU - Horvat, Milena AU - Horvat M AD - Department of Environmental Sciences, Jozef Stefan Institute, Ljubljana, Slovenia. FAU - Hakkola, Jukka AU - Hakkola J AD - Research Unit of Biomedicine, University of Oulu, Oulu, Finland. AD - Medical Research Centre Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland. FAU - Jarvelin, Marjo-Riitta AU - Jarvelin MR AD - Institute of Health Sciences, University of Oulu, Oulu, Finland. AD - Biocentre Oulu, University of Oulu, Oulu, Finland. AD - Department of Epidemiology and Biostatistics, MRC PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK. FAU - Rautio, Arja AU - Rautio A AD - Centre for Arctic Medicine, Thule Institute, University of Oulu, Oulu, Finland. LA - eng PT - Journal Article DEP - 20161024 PL - Germany TA - Environ Sci Pollut Res Int JT - Environmental science and pollution research international JID - 9441769 RN - 00BH33GNGH (Cadmium) RN - 2P299V784P (Lead) RN - FXS1BY2PGL (Mercury) RN - H6241UJ22B (Selenium) RN - N712M78A8G (Arsenic) SB - IM MH - Adult MH - Arsenic/*blood MH - Cadmium/*blood MH - *Diet MH - Feeding Behavior MH - Female MH - Finland MH - Habits MH - Humans MH - Lead/*blood MH - *Life Style MH - Male MH - Mercury/*blood MH - Middle Aged MH - Prospective Studies MH - Selenium/blood MH - Socioeconomic Factors MH - Surveys and Questionnaires OTO - NOTNLM OT - Metalloids OT - Northern Finland birth cohort 1966 OT - Toxic metals EDAT- 2016/10/26 06:00 MHDA- 2017/04/14 06:00 CRDT- 2016/10/26 06:00 PHST- 2016/04/22 00:00 [received] PHST- 2016/10/03 00:00 [accepted] PHST- 2016/10/26 06:00 [pubmed] PHST- 2017/04/14 06:00 [medline] PHST- 2016/10/26 06:00 [entrez] AID - 10.1007/s11356-016-7824-5 [pii] AID - 10.1007/s11356-016-7824-5 [doi] PST - ppublish SO - Environ Sci Pollut Res Int. 2017 Jan;24(2):1347-1362. doi: 10.1007/s11356-016-7824-5. Epub 2016 Oct 24.