PMID- 27778461 OWN - NLM STAT- MEDLINE DCOM- 20180102 LR - 20220408 IS - 1755-3768 (Electronic) IS - 1755-375X (Linking) VI - 95 IP - 7 DP - 2017 Nov TI - Retinal pigment epithelium wound healing after traumatic choroidal rupture. PG - e582-e586 LID - 10.1111/aos.13300 [doi] AB - PURPOSE: The aim of this study was to investigate wound healing in the retinal pigment epithelium (RPE) after traumatic indirect choroidal rupture using fundus autofluorescence (FAF) and spectral-domain optical coherence tomography (SD-OCT). METHODS: A total of 14 eyes of 14 patients with traumatic indirect choroidal rupture were included. Baseline and last follow-up FAF images were compared to evaluate the extent of RPE healing after choroidal rupture, and associated morphologic characteristics were examined by SD-OCT. RESULTS: The size of the RPE lesion was reduced in five eyes. The change occurred in the fovea in four eyes and in the macula in three eyes. The change was noted in both the fovea and the macula in two eyes; in these cases, the changes were more prominent in the fovea than in the macula. Extra-macular lesions and lesions with deep choroidal involvement did not show any reduction in size. Choroidal neovascularization (CNV) developed in seven eyes. There was no extra-macular CNV. CONCLUSION: Retinal pigment epithelium (RPE) wound healing after traumatic choroidal rupture is affected by location and extent of the lesion. CI - (c) 2016 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd. FAU - Shin, Joo Youn AU - Shin JY AD - Department of Ophthalmology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, South Korea. AD - Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Seoul, South Korea. FAU - Chung, Byunghoon AU - Chung B AD - Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Seoul, South Korea. FAU - Na, Yun Hyup AU - Na YH AD - Department of Ophthalmology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, South Korea. FAU - Lee, Jonghyun AU - Lee J AD - Department of Ophthalmology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, South Korea. FAU - Chung, Hyewon AU - Chung H AD - Department of Ophthalmology, Konkuk University School of Medicine, Seoul, South Korea. FAU - Byeon, Suk Ho AU - Byeon SH AD - Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Seoul, South Korea. LA - eng PT - Journal Article PT - Observational Study DEP - 20161024 PL - England TA - Acta Ophthalmol JT - Acta ophthalmologica JID - 101468102 SB - IM MH - Adolescent MH - Adult MH - Child MH - Choroid/*injuries MH - Choroidal Neovascularization/etiology/pathology MH - Eye Injuries/complications/*pathology MH - Female MH - Fluorescein Angiography/*methods MH - Follow-Up Studies MH - Fundus Oculi MH - Humans MH - Male MH - Middle Aged MH - Retinal Pigment Epithelium/injuries/*pathology MH - Retrospective Studies MH - Rupture MH - Time Factors MH - Tomography, Optical Coherence/*methods MH - *Wound Healing MH - Young Adult OTO - NOTNLM OT - choroidal rupture OT - fundus autofluorescence OT - optical coherence tomography OT - retinal pigment epithelium OT - wound healing EDAT- 2016/10/26 06:00 MHDA- 2018/01/03 06:00 CRDT- 2016/10/26 06:00 PHST- 2016/01/05 00:00 [received] PHST- 2016/09/25 00:00 [accepted] PHST- 2016/10/26 06:00 [pubmed] PHST- 2018/01/03 06:00 [medline] PHST- 2016/10/26 06:00 [entrez] AID - 10.1111/aos.13300 [doi] PST - ppublish SO - Acta Ophthalmol. 2017 Nov;95(7):e582-e586. doi: 10.1111/aos.13300. Epub 2016 Oct 24.