PMID- 27781297 OWN - NLM STAT- MEDLINE DCOM- 20170427 LR - 20181202 IS - 1540-8183 (Electronic) IS - 0896-4327 (Linking) VI - 30 IP - 1 DP - 2017 Feb TI - Safety and Efficacy of Using a Single Transradial MAC Guiding Catheter for Coronary Angiography and Intervention in Patients with ST Elevation Myocardial Infarction. PG - 33-42 LID - 10.1111/joic.12346 [doi] AB - BACKGROUND: There are limited data on the impact of using a single dedicated radial guiding catheter in primary percutaneous coronary intervention (PCI) via radial access. OBJECTIVES: To investigate the effect of using a single guiding catheter (MAC 3.5) for left and right coronary angiography and intervention on catheterization laboratory door to balloon (C2B) time in patients with ST elevation myocardial infarction (STEMI). METHODS: Three hundred and sixty patients were randomized (1:1) to using a single MAC3.5 guiding catheter (MAC group) or diagnostic Tiger catheter first for coronary angiography followed by guiding catheter selection (control group) for intervention. The primary outcomes were C2B. The secondary outcomes were major adverse cardiac events (MACE) at 30 days and 6 months. RESULTS: Median C2B time (16.6 min, interquartile range [IQR] 14.3-20.2 min vs 19.0 min, IQR 14.3-23.1 min; P < 0.001), total procedure time (31.0 min, IQR 26.4-37.7 min vs 34.8 min, IQR 29.7-42.5 min, P < 0.001), and overall fluoroscopy time (8.0 min, IQR 6.4-10.4 min vs 8.8 min, IQR 6.5-12.2, P = 0.04) were significantly reduced in MAC Group. Contrast consumption were similar among both groups (103 +/- 37 ml vs 110 +/- 41 ml, P = 0.16). The MACE rate in MAC group and control group was 3.3 versus 4.4% (P = 0.586) at 30 days and 3.3 versus 5.0% (P = 0.429) at 6 months, respectively. CONCLUSIONS: A single MAC3.5 guiding catheter for coronary angiography and intervention can shorten C2B time, procedure time, and fluoroscopy time. (RAPID study; NCT01759043). CI - (c) 2016, Wiley Periodicals, Inc. FAU - Guo, Jincheng AU - Guo J AD - Department of Cardiology, Beijing Luhe Hospital, Capital Medical University, Beijing, China. FAU - Chen, Wenming AU - Chen W AD - Department of Cardiology, Beijing Luhe Hospital, Capital Medical University, Beijing, China. FAU - Wang, Guozhong AU - Wang G AD - Department of Cardiology, Beijing Luhe Hospital, Capital Medical University, Beijing, China. FAU - Liu, Zijing AU - Liu Z AD - Department of Cardiology, Beijing Luhe Hospital, Capital Medical University, Beijing, China. FAU - Hao, Minghui AU - Hao M AD - Department of Cardiology, Beijing Luhe Hospital, Capital Medical University, Beijing, China. FAU - Xu, Min AU - Xu M AD - Department of Cardiology, Beijing Luhe Hospital, Capital Medical University, Beijing, China. FAU - Zhu, Fuli AU - Zhu F AD - Department of Cardiology, Beijing Luhe Hospital, Capital Medical University, Beijing, China. LA - eng SI - ClinicalTrials.gov/NCT01759043 PT - Journal Article PT - Randomized Controlled Trial DEP - 20161025 PL - United States TA - J Interv Cardiol JT - Journal of interventional cardiology JID - 8907826 SB - IM MH - Aged MH - *Angioplasty, Balloon, Coronary MH - *Cardiac Catheters MH - Coronary Angiography/*instrumentation MH - Female MH - Fluoroscopy MH - Humans MH - Male MH - Middle Aged MH - ST Elevation Myocardial Infarction/*diagnostic imaging/*therapy MH - Safety MH - Time Factors MH - Treatment Outcome EDAT- 2016/10/27 06:00 MHDA- 2017/04/28 06:00 CRDT- 2016/10/27 06:00 PHST- 2016/10/27 06:00 [pubmed] PHST- 2017/04/28 06:00 [medline] PHST- 2016/10/27 06:00 [entrez] AID - 10.1111/joic.12346 [doi] PST - ppublish SO - J Interv Cardiol. 2017 Feb;30(1):33-42. doi: 10.1111/joic.12346. Epub 2016 Oct 25.