PMID- 27788459 OWN - NLM STAT- MEDLINE DCOM- 20171117 LR - 20190318 IS - 1872-7123 (Electronic) IS - 0165-1781 (Linking) VI - 246 DP - 2016 Dec 30 TI - The prevalence of diabetes mellitus type 2 in people with alcohol use disorders: a systematic review and large scale meta-analysis. PG - 394-400 LID - S0165-1781(16)30557-1 [pii] LID - 10.1016/j.psychres.2016.10.010 [doi] AB - Type 2 Diabetes Mellitus (T2DM) is highly predictive of cardiovascular diseases and is associated with worse quality of life and increased healthcare utilisation. The current meta-analysis aimed to (i) describe the pooled prevalence of T2DM in people with alcohol use disorders (AUDs), (ii) investigate the impact of demographic, clinical and treatment factors, and (iii) compare T2DM prevalences in AUDs versus the general population. The trim and fill adjusted pooled T2DM prevalence among 3998 people with AUDs (age range 34.8-51.1 years; 76.6% male) (N studies=7) was 12.4% (95%CI=11.8-13.9%). Higher T2DM prevalences were observed in studies with a higher mean age and a higher percentage of male participants, and in studies with self- or physician reported T2DM assessment. A trend for higher T2DM prevalences was found in inpatient settings, in studies assessing T2DM with the gold-standard oral glucose tolerance test compared with fasting glucose only, and with studies including patients with a higher percentage of physical co-morbidity. Although healthy control data are lacking, the pooled prevalence is similar to that observed in people with severe mental illness who are considered a high-risk group. Routine screening and multidisciplinary management of T2DM in people with AUDs is needed. CI - Copyright (c) 2016 Elsevier Ireland Ltd. All rights reserved. FAU - Vancampfort, Davy AU - Vancampfort D AD - KU Leuven - University of Leuven, Department of Rehabilitation Sciences, Leuven, Belgium; KU Leuven - University of Leuven, University Psychiatric Centre KU Leuven, Leuven-Kortenberg, Belgium. Electronic address: davy.vancampfort@uc-kortenberg.be. FAU - Mugisha, James AU - Mugisha J AD - Butabika National Referral and Mental Health Hospital, Kampala, Uganda; Kyambogo University, Kampala, Uganda. FAU - Hallgren, Mats AU - Hallgren M AD - Department of Public Health Sciences, Karolinksa Institute, Stockholm, Sweden. FAU - De Hert, Marc AU - De Hert M AD - KU Leuven - University of Leuven, University Psychiatric Centre KU Leuven, Leuven-Kortenberg, Belgium. FAU - Probst, Michel AU - Probst M AD - KU Leuven - University of Leuven, Department of Rehabilitation Sciences, Leuven, Belgium. FAU - Monsieur, Dirk AU - Monsieur D AD - KU Leuven - University of Leuven, University Psychiatric Centre KU Leuven, Leuven-Kortenberg, Belgium. FAU - Stubbs, Brendon AU - Stubbs B AD - Physiotherapy Department, South London and Maudsley NHS Foundation Trust, London, UK; Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, UK. LA - eng PT - Journal Article PT - Meta-Analysis PT - Review PT - Systematic Review DEP - 20161011 PL - Ireland TA - Psychiatry Res JT - Psychiatry research JID - 7911385 SB - IM MH - Adult MH - Alcohol-Related Disorders/*epidemiology MH - *Comorbidity MH - Diabetes Mellitus, Type 2/*epidemiology MH - Female MH - Humans MH - Male MH - Middle Aged EDAT- 2016/10/28 06:00 MHDA- 2017/11/29 06:00 CRDT- 2016/10/28 06:00 PHST- 2016/04/05 00:00 [received] PHST- 2016/10/10 00:00 [accepted] PHST- 2016/10/28 06:00 [pubmed] PHST- 2017/11/29 06:00 [medline] PHST- 2016/10/28 06:00 [entrez] AID - S0165-1781(16)30557-1 [pii] AID - 10.1016/j.psychres.2016.10.010 [doi] PST - ppublish SO - Psychiatry Res. 2016 Dec 30;246:394-400. doi: 10.1016/j.psychres.2016.10.010. Epub 2016 Oct 11.