PMID- 27789774
OWN - NLM
STAT- MEDLINE
DCOM- 20180223
LR  - 20180223
IS  - 1522-1601 (Electronic)
IS  - 0161-7567 (Linking)
VI  - 122
IP  - 5
DP  - 2017 May 1
TI  - Postexercise muscle glycogen resynthesis in humans.
PG  - 1055-1067
LID - 10.1152/japplphysiol.00860.2016 [doi]
AB  - Since the pioneering studies conducted in the 1960s in which glycogen status was 
      investigated using the muscle biopsy technique, sports scientists have developed 
      a sophisticated appreciation of the role of glycogen in cellular adaptation and 
      exercise performance, as well as sites of storage of this important metabolic 
      fuel. While sports nutrition guidelines have evolved during the past decade to 
      incorporate sport-specific and periodized manipulation of carbohydrate (CHO) 
      availability, athletes attempt to maximize muscle glycogen synthesis between 
      important workouts or competitive events so that fuel stores closely match the 
      demands of the prescribed exercise. Therefore, it is important to understand the 
      factors that enhance or impair this biphasic process. In the early postexercise 
      period (0-4 h), glycogen depletion provides a strong drive for its own 
      resynthesis, with the provision of CHO (~1 g/kg body mass) optimizing this 
      process. During the later phase of recovery (4-24 h), CHO intake should meet the 
      anticipated fuel needs of the training/competition, with the type, form, and 
      pattern of intake being less important than total intake. Dietary strategies that 
      can enhance glycogen synthesis from suboptimal amounts of CHO or energy intake 
      are of practical interest to many athletes; in this scenario, the coingestion of 
      protein with CHO can assist glycogen storage. Future research should identify 
      other factors that enhance the rate of synthesis of glycogen storage in a limited 
      time frame, improve glycogen storage from a limited CHO intake, or increase 
      muscle glycogen supercompensation.
CI  - Copyright (c) 2017 the American Physiological Society.
FAU - Burke, Louise M
AU  - Burke LM
AD  - Centre for Exercise and Nutrition, Mary MacKillop Institute for Health Research, 
      Australian Catholic University, Melbourne, Victoria, Australia.
AD  - Department of Sport Nutrition, Australian Institute of Sport, Belconnen, 
      Australia.
FAU - van Loon, Luc J C
AU  - van Loon LJC
AD  - Centre for Exercise and Nutrition, Mary MacKillop Institute for Health Research, 
      Australian Catholic University, Melbourne, Victoria, Australia.
AD  - NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht 
      University Medical Centre, Maastricht, The Netherlands; and.
FAU - Hawley, John A
AU  - Hawley JA
AD  - Centre for Exercise and Nutrition, Mary MacKillop Institute for Health Research, 
      Australian Catholic University, Melbourne, Victoria, Australia; 
      john.hawley@acu.edu.au.
AD  - Research Institute for Sport and Exercise Sciences, Liverpool John Moores 
      University, Liverpool, United Kingdom.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20161027
PL  - United States
TA  - J Appl Physiol (1985)
JT  - Journal of applied physiology (Bethesda, Md. : 1985)
JID - 8502536
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Proteins)
RN  - 9005-79-2 (Glycogen)
SB  - IM
MH  - Diet/methods
MH  - Dietary Carbohydrates/metabolism
MH  - Dietary Proteins/metabolism
MH  - Energy Intake/physiology
MH  - Exercise/*psychology
MH  - Glycogen/*metabolism
MH  - Humans
MH  - Muscle, Skeletal/*metabolism/*physiology
MH  - Sports/physiology
OTO - NOTNLM
OT  - carbohydrate intake
OT  - carbohydrate loading
OT  - glycogen synthase
OT  - refueling
EDAT- 2016/11/01 06:00
MHDA- 2018/02/24 06:00
CRDT- 2016/11/01 06:00
PHST- 2016/09/22 00:00 [received]
PHST- 2016/10/12 00:00 [revised]
PHST- 2016/10/23 00:00 [accepted]
PHST- 2016/11/01 06:00 [pubmed]
PHST- 2018/02/24 06:00 [medline]
PHST- 2016/11/01 06:00 [entrez]
AID - japplphysiol.00860.2016 [pii]
AID - 10.1152/japplphysiol.00860.2016 [doi]
PST - ppublish
SO  - J Appl Physiol (1985). 2017 May 1;122(5):1055-1067. doi: 
      10.1152/japplphysiol.00860.2016. Epub 2016 Oct 27.