PMID- 27799759
OWN - NLM
STAT- MEDLINE
DCOM- 20170809
LR  - 20220409
IS  - 1178-2005 (Electronic)
IS  - 1176-9106 (Print)
IS  - 1176-9106 (Linking)
VI  - 11
DP  - 2016
TI  - Is the 1-minute sit-to-stand test a good tool for the evaluation of the impact of 
      pulmonary rehabilitation? Determination of the minimal important difference in 
      COPD.
PG  - 2609-2616
AB  - BACKGROUND: The 1-minute sit-to-stand (STS) test could be valuable to assess the 
      level of exercise tolerance in chronic obstructive pulmonary disease (COPD). 
      There is a need to provide the minimal important difference (MID) of this test in 
      pulmonary rehabilitation (PR). METHODS: COPD patients undergoing the 1-minute STS 
      test before PR were included. The test was performed at baseline and the end of 
      PR, as well as the 6-minute walk test, and the quadriceps maximum voluntary 
      contraction (QMVC). Home and community-based programs were conducted as 
      recommended. Responsiveness to PR was determined by the difference in the 
      1-minute STS test between baseline and the end of PR. The MID was evaluated using 
      distribution and anchor-based methods. RESULTS: Forty-eight COPD patients were 
      included. At baseline, the significant predictors of the number of 1-minute STS 
      repetitions were the 6-minute walk distance (6MWD) (r=0.574; P<10(-3)), age 
      (r=-0.453; P=0.001), being on long-term oxygen treatment (r=-0.454; P=0.017), and 
      the QMVC (r=0.424; P=0.031). The multivariate analysis explained 75.8% of the 
      variance of 1-minute STS repetitions. The improvement of the 1-minute STS 
      repetitions at the end of PR was 3.8+/-4.2 (P<10(-3)). It was mainly correlated 
      with the change in QMVC (r=0.572; P=0.004) and 6MWD (r=0.428; P=0.006). Using the 
      distribution-based analysis, an MID of 1.9 (standard error of measurement method) 
      or 3.1 (standard deviation method) was found. With the 6MWD as anchor, the 
      receiver operating characteristic curve identified the MID for the change in 
      1-minute STS repetitions at 2.5 (sensibility: 80%, specificity: 60%) with area 
      under curve of 0.716. CONCLUSION: The 1-minute STS test is simple and sensitive 
      to measure the efficiency of PR. An improvement of at least three repetitions is 
      consistent with physical benefits after PR.
FAU - Vaidya, Trija
AU  - Vaidya T
AD  - Explorations Fonctionnelles Respiratoires, l'institut du thorax, CHU de Nantes; 
      Universite de Poitiers, Laboratoire MOVE EA 6314, F-86000 Poitiers.
FAU - de Bisschop, Claire
AU  - de Bisschop C
AD  - Universite de Poitiers, Laboratoire MOVE EA 6314, F-86000 Poitiers.
FAU - Beaumont, Marc
AU  - Beaumont M
AD  - Pulmonary Rehabilitation Unit, Morlaix Hospital Centre; European University of 
      Occidental Brittany, EA3878, Brest.
FAU - Ouksel, Hakima
AU  - Ouksel H
AD  - Service de Pneumologie, CHU d'Angers, Angers.
FAU - Jean, Veronique
AU  - Jean V
AD  - Service de Rehabilitation Respiratoire, Soins de Suite et Reeducation, CHU de 
      Nantes.
FAU - Dessables, Francois
AU  - Dessables F
AD  - Service de Rehabilitation Respiratoire, la Tourmaline, UGECAM.
FAU - Chambellan, Arnaud
AU  - Chambellan A
AD  - Explorations Fonctionnelles Respiratoires, l'institut du thorax, CHU de Nantes; 
      Universite de Nantes, Laboratory EA 4334 "Mouvement, Interactions, Performance," 
      Nantes, France.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20161019
PL  - New Zealand
TA  - Int J Chron Obstruct Pulmon Dis
JT  - International journal of chronic obstructive pulmonary disease
JID - 101273481
SB  - IM
MH  - Aged
MH  - Area Under Curve
MH  - *Exercise Test
MH  - *Exercise Tolerance
MH  - Female
MH  - Forced Expiratory Volume
MH  - France
MH  - Humans
MH  - Lung/*physiopathology
MH  - Male
MH  - Middle Aged
MH  - *Minimal Clinically Important Difference
MH  - Multivariate Analysis
MH  - Muscle Contraction
MH  - Muscle Strength
MH  - Oxygen Inhalation Therapy
MH  - Predictive Value of Tests
MH  - Pulmonary Disease, Chronic Obstructive/*diagnosis/physiopathology/*rehabilitation
MH  - Quadriceps Muscle/physiopathology
MH  - ROC Curve
MH  - Recovery of Function
MH  - *Respiratory Therapy/methods
MH  - Treatment Outcome
MH  - Walk Test
PMC - PMC5079690
OTO - NOTNLM
OT  - 6-minute walk test
OT  - COPD
OT  - exercise tolerance
OT  - pulmonary rehabilitation
OT  - sit-to-stand test
COIS- The authors report no conflicts of interest in this work.
EDAT- 2016/11/02 06:00
MHDA- 2017/08/10 06:00
PMCR- 2016/10/19
CRDT- 2016/11/02 06:00
PHST- 2016/11/02 06:00 [pubmed]
PHST- 2017/08/10 06:00 [medline]
PHST- 2016/11/02 06:00 [entrez]
PHST- 2016/10/19 00:00 [pmc-release]
AID - copd-11-2609 [pii]
AID - 10.2147/COPD.S115439 [doi]
PST - epublish
SO  - Int J Chron Obstruct Pulmon Dis. 2016 Oct 19;11:2609-2616. doi: 
      10.2147/COPD.S115439. eCollection 2016.