PMID- 27801487 OWN - NLM STAT- MEDLINE DCOM- 20170601 LR - 20170601 IS - 0041-4131 (Print) IS - 0041-4131 (Linking) VI - 94 IP - 5 DP - 2016 May TI - Prognostic factors of advanced stage non-small-cell lung cancer. PG - 360-367 AB - Background Lung cancer is the main cause of death from cancer in the world. The 5-year survival is about 15%. Despite the progress of medicine the mortality rate decreased only marginally. This poor prognosis is due to late diagnosis. Aim To evaluate overall survival and prognostic factors in patients locally advanced or metastatic non small cell lung cancer (NSCLC). Methods Retrospective study including 180 patients with non-small cell lung cancer hospitalized in the department of Charles Nicolle Hospital of Tunis between January 2007 and December 2014. Results The mean age was 61.5 years with a male predominance (93.3%). The median overall survival was 6 months. The poor prognostic factors were the performans status (PS) and early delays of management (<30 days). The factors that improve survival were surgical treatment and delays of management more than 45 days. Conclusion The prognostic factors in locally advanced and metastatic NSLC in our patient were: PS, management delay and treatment. These factors should be considered in management of patient with advanced stage NSCLC. FAU - Ben Amar, Jihen AU - Ben Amar J FAU - Ben Safta, Boutheina AU - Ben Safta B FAU - Zaibi, Haifa AU - Zaibi H FAU - Dhahri, Besma AU - Dhahri B FAU - Baccar, Mohamed Ali AU - Baccar MA FAU - Azzabi, Saloua AU - Azzabi S LA - eng PT - Journal Article PL - Tunisia TA - Tunis Med JT - La Tunisie medicale JID - 0413766 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Carcinoma, Non-Small-Cell Lung/*pathology/therapy MH - Female MH - Humans MH - Lung Neoplasms/*pathology/therapy MH - Male MH - Middle Aged MH - Neoplasm Staging MH - Prognosis MH - Retrospective Studies MH - Survival Rate MH - Time Factors EDAT- 2016/11/02 06:00 MHDA- 2017/06/02 06:00 CRDT- 2016/11/02 06:00 PHST- 2016/11/02 06:00 [pubmed] PHST- 2017/06/02 06:00 [medline] PHST- 2016/11/02 06:00 [entrez] AID - /article-medicale-tunisie.php?article=3041 [pii] PST - ppublish SO - Tunis Med. 2016 May;94(5):360-367.