PMID- 27813017
OWN - NLM
STAT- MEDLINE
DCOM- 20171211
LR  - 20240213
IS  - 1873-4626 (Electronic)
IS  - 1091-255X (Linking)
VI  - 21
IP  - 3
DP  - 2017 Mar
TI  - Tri-comparison of Laparoscopic Nissen, Hill, and Nissen-Hill Hybrid Repairs for 
      Uncomplicated Gastroesophageal Reflux Disease.
PG  - 434-440
LID - 10.1007/s11605-016-3317-6 [doi]
AB  - BACKGROUND: A randomized controlled trial (RCT) showed that laparoscopic Nissen 
      fundoplication (LNF) and Hill (LHR) repairs are equivalent in treating 
      uncomplicated GERD. We combined both repairs to create a laparoscopic Nissen-Hill 
      Hybrid repair (HYB). The purpose of this study is to compare clinical and 
      objective outcomes of a matched group of HYB to the two cohorts of the RCT. 
      METHODS: A retrospective analysis of prospectively collected data from the RCT 
      and a prospectively collected data base was performed. Data were collected 
      preoperatively, postoperatively short-term (ST) at 6 weeks and mid-term (MT) at 
      6-12 months. Evaluation was standardized according to the RCT and included three 
      quality of life metrics (QOLRAD, GERD-HRQL, Dysphagia), endoscopy, manometry, pH 
      testing, and barium swallow. RESULTS: There were 51 HYB, 46 LNF, and 56 LHR 
      patients. Age, BMI, follow-up, and gender were comparable. QOLRAD, HRQL, PPI use, 
      DeMeester scores, and pH% time <4 significantly improved in all groups and were 
      equivalent. Anatomic recurrence was seen in five LNF, four LHR, and two HYB 
      patients. Reoperations were performed in three LHR, two LNF, and zero HYB 
      patients. CONCLUSION: Tri-comparison shows that HYB is a promising alternative to 
      LHR and LNF. Side effects were not increased and there were fewer reoperations 
      for failure.
FAU - Schneider, Andreas M
AU  - Schneider AM
AD  - Division of Thoracic Surgery, Swedish Cancer Institute and Medical Center, 1101 
      Madison St. Suite 900, Seattle, WA, 98104, USA.
FAU - Aye, Ralph W
AU  - Aye RW
AD  - Division of Thoracic Surgery, Swedish Cancer Institute and Medical Center, 1101 
      Madison St. Suite 900, Seattle, WA, 98104, USA. ralph.aye@swedish.org.
FAU - Wilshire, Candice L
AU  - Wilshire CL
AD  - Division of Thoracic Surgery, Swedish Cancer Institute and Medical Center, 1101 
      Madison St. Suite 900, Seattle, WA, 98104, USA.
FAU - Farivar, Alexander S
AU  - Farivar AS
AD  - Division of Thoracic Surgery, Swedish Cancer Institute and Medical Center, 1101 
      Madison St. Suite 900, Seattle, WA, 98104, USA.
FAU - Louie, Brian E
AU  - Louie BE
AD  - Division of Thoracic Surgery, Swedish Cancer Institute and Medical Center, 1101 
      Madison St. Suite 900, Seattle, WA, 98104, USA.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20161103
PL  - Netherlands
TA  - J Gastrointest Surg
JT  - Journal of gastrointestinal surgery : official journal of the Society for Surgery 
      of the Alimentary Tract
JID - 9706084
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Adult
MH  - Esophageal pH Monitoring
MH  - Female
MH  - Fundoplication/*methods
MH  - Gastroesophageal Reflux/drug therapy/*surgery
MH  - Humans
MH  - Hydrogen-Ion Concentration
MH  - Laparoscopy/*methods
MH  - Male
MH  - Manometry
MH  - Middle Aged
MH  - Proton Pump Inhibitors/therapeutic use
MH  - *Quality of Life
MH  - Randomized Controlled Trials as Topic
MH  - Recurrence
MH  - Reoperation
MH  - Retrospective Studies
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Fundoplication
OT  - Gastroesophageal reflux
OT  - Quality of life
OT  - Recurrence
OT  - Reoperation
EDAT- 2016/11/05 06:00
MHDA- 2017/12/12 06:00
CRDT- 2016/11/05 06:00
PHST- 2016/08/01 00:00 [received]
PHST- 2016/10/26 00:00 [accepted]
PHST- 2016/11/05 06:00 [pubmed]
PHST- 2017/12/12 06:00 [medline]
PHST- 2016/11/05 06:00 [entrez]
AID - S1091-255X(23)02590-8 [pii]
AID - 10.1007/s11605-016-3317-6 [doi]
PST - ppublish
SO  - J Gastrointest Surg. 2017 Mar;21(3):434-440. doi: 10.1007/s11605-016-3317-6. Epub 
      2016 Nov 3.