PMID- 27819783
OWN - NLM
STAT- MEDLINE
DCOM- 20170503
LR  - 20170503
IS  - 2448-5667 (Electronic)
IS  - 0443-5117 (Linking)
VI  - 54
IP  - 6
DP  - 2016 Nov-Dec
TI  - [Acute coronary syndromes in Latin America: lessons from the ACCESS registry].
PG  - 726-737
AB  - BACKGROUND: Evidence of the clinical characteristics, treatment and outcomes 
      among Latin American (LA) patients with acute coronary syndromes (ACS) is scarce. 
      METHODS: ACCESS, international prospective multicenter registry to evaluate risk 
      stratification, management and outcomes in ACS (unstable angina or non-ST 
      elevation myocardial infarction [UA/NSTEMI] or ST elevation myocardial infarction 
      [STEMI]) in developing countries. Primary endpoint: all-cause death at 1 year; 
      all-cause mortality within 30 days was also recorded, Patients with acute 
      ischemic symptoms within 24 hours of symptoms onset and electrocardiographic 
      evidence of ischemia were enrolled. Coronary artery disease was proved by 
      positive invasive or non-invasive tests. RESULTS: Between 2007 and 2008, 4436 
      patients with ACS (2562 UA/NSTEMI and 2374 STEMI) from eight LA countries. On 
      admission, acute symptoms were identified in 79 % and 90%, respectively. Both 
      groups had a long delay from symptom onset to hospital arrival. Low access to 
      pharmacological (29%) and mechanical reperfusion (32%) were observed. At 
      admission, rates of evidence-based treatment were low in all groups. The most 
      common in-hospital complications were heart failure (10% UA/NSTEMI and 20% STEMI) 
      and recurrent ischemia (8% and 11%). Mortality at 30 days was 2% and 8% at 1 
      year. CONCLUSION: ACCESS registry provides contemporary information of patients 
      with ACS in LA and their hospital management and subsequent clinical outcomes.
FAU - Martinez-Sanchez, Carlos
AU  - Martinez-Sanchez C
AD  - Servicio de Urgencias y Unidad Coronaria, Instituto Nacional de Cardiologia 
      "Ignacio Chavez", Ciudad de Mexico, Mexico. jerjes@prodigy.net.mx.
FAU - Jerjes-Sanchez, Carlos
AU  - Jerjes-Sanchez C
FAU - Nicolau, Jose Carlos
AU  - Nicolau JC
FAU - Bazzino, Oscar
AU  - Bazzino O
FAU - Antepara, Norka
AU  - Antepara N
FAU - Marmol, Ricardo
AU  - Marmol R
CN  - ACCESS Investigators
LA  - spa
PT  - Journal Article
PT  - Multicenter Study
PT  - Observational Study
TT  - Sindromes coronarios agudos en Latinoamerica: lecciones aprendidas del registro 
      ACCESS.
PL  - Mexico
TA  - Rev Med Inst Mex Seguro Soc
JT  - Revista medica del Instituto Mexicano del Seguro Social
JID - 101243727
SB  - IM
MH  - Acute Coronary Syndrome/diagnosis/*mortality/therapy
MH  - Adult
MH  - Aged
MH  - Electrocardiography
MH  - Female
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Latin America/epidemiology
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Registries
OTO - NOTNLM
OT  - Acute coronary syndrome
OT  - Ischemic heart disease
OT  - Myocardial infarction
OT  - Unstable angina
EDAT- 2016/11/08 06:00
MHDA- 2017/05/04 06:00
CRDT- 2016/11/08 06:00
PHST- 2016/11/08 06:00 [entrez]
PHST- 2016/11/08 06:00 [pubmed]
PHST- 2017/05/04 06:00 [medline]
PST - ppublish
SO  - Rev Med Inst Mex Seguro Soc. 2016 Nov-Dec;54(6):726-737.