PMID- 27823672
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20180104
LR  - 20180104
IS  - 1873-4324 (Electronic)
IS  - 0003-2670 (Linking)
VI  - 946
DP  - 2016 Nov 23
TI  - Fabrication of l-cysteine-capped CdTe quantum dots based ratiometric fluorescence 
      nanosensor for onsite visual determination of trace TNT explosive.
PG  - 80-87
LID - S0003-2670(16)31190-4 [pii]
LID - 10.1016/j.aca.2016.10.007 [doi]
AB  - New strategies for onsite determination of trace 2,4,6-trinitrotoluene (TNT) 
      explosives have become a research hotspot for homeland security needs against 
      terrorism and environmental concerns. Herein, we designed a ratiometric 
      fluorescence nanohybrid comprising 3-mercaptopropionic acid-capped green-emitting 
      CdTe quantum dots (gQDs) encapsulated into SiO(2) sphere and l-cysteine 
      (Lcys)-capped red-emitting CdTe QDs (rQDs) conjugated onto SiO(2) surface. The 
      surface Lcys can be used as not only the stabilizer of the rQDs but also the 
      primary amine provider which can react with TNT to form Meisenheimer complexes. 
      Without any additional surface modification procedure, the fluorescence of rQDs 
      equipped with Lcys was selectively quenched by TNT because electrons of the rQDs 
      transferred to TNT molecules due to the formation of Meisenheimer complexes. 
      Meanwhile, the embedded gQDs always remained constant. Upon exposure to 
      increasing amounts of TNT, the fluorescence of rQDs could be gradually quenched 
      and consequently the logarithm of the dual emission intensity ratios exhibited a 
      good linear negative correlation with TNT concentration over a range of 10 nM-8 
      muM with a low detection limit of 3.3 nM. One can perform onsite visual 
      determination of TNT with high resolution because the ratiometric fluorescence 
      nanosensing system exhibited obvious fluorescence color changes. This sensing 
      strategy has been successfully applied in real samples and already integrated in 
      a filter paper-based assay, which enables potential fields use application 
      featuring easy handling and cost-effectiveness.
CI  - Copyright (c) 2016 Elsevier B.V. All rights reserved.
FAU - Qian, Jing
AU  - Qian J
AD  - School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 
      212013, PR China.
FAU - Hua, Mengjuan
AU  - Hua M
AD  - School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 
      212013, PR China.
FAU - Wang, Chengquan
AU  - Wang C
AD  - Changzhou College of Information Technology, Changzhou 213164, PR China.
FAU - Wang, Kan
AU  - Wang K
AD  - School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 
      212013, PR China.
FAU - Liu, Qian
AU  - Liu Q
AD  - School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 
      212013, PR China.
FAU - Hao, Nan
AU  - Hao N
AD  - School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 
      212013, PR China.
FAU - Wang, Kun
AU  - Wang K
AD  - School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 
      212013, PR China. Electronic address: wangkun@ujs.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20161014
PL  - Netherlands
TA  - Anal Chim Acta
JT  - Analytica chimica acta
JID - 0370534
OTO - NOTNLM
OT  - 2,4,6-Trinitrotoluene
OT  - CdTe quantum dots
OT  - Nanohybrid
OT  - Ratiometric fluorescence
OT  - Visual determination
EDAT- 2016/11/09 06:00
MHDA- 2016/11/09 06:01
CRDT- 2016/11/09 06:00
PHST- 2016/08/16 00:00 [received]
PHST- 2016/09/29 00:00 [revised]
PHST- 2016/10/03 00:00 [accepted]
PHST- 2016/11/09 06:00 [entrez]
PHST- 2016/11/09 06:00 [pubmed]
PHST- 2016/11/09 06:01 [medline]
AID - S0003-2670(16)31190-4 [pii]
AID - 10.1016/j.aca.2016.10.007 [doi]
PST - ppublish
SO  - Anal Chim Acta. 2016 Nov 23;946:80-87. doi: 10.1016/j.aca.2016.10.007. Epub 2016 
      Oct 14.