PMID- 27823725
OWN - NLM
STAT- MEDLINE
DCOM- 20171127
LR  - 20180501
IS  - 1878-5506 (Electronic)
IS  - 1389-9457 (Linking)
VI  - 25
DP  - 2016 Sep
TI  - Screening, diagnosis, and management of obstructive sleep apnea in 
      dangerous-goods truck drivers: to be aware or not?
PG  - 98-104
LID - S1389-9457(16)30153-8 [pii]
LID - 10.1016/j.sleep.2016.05.015 [doi]
AB  - OBJECTIVE: The aims of this study were: to evaluate a homogeneous sample of truck 
      drivers of dangerous goods (TDDGs) in order to assess the prevalence of 
      obstructive sleep apnea (OSA), and to verify the secondary risk of motor vehicle 
      accidents (MVAs) and near miss accidents (NMAs) in this population. METHODS: A 
      sample of 283 male TDDGs was evaluated. None of the subjects reported OSA 
      symptoms before screening. Clinical and physical evaluation, Epworth Sleepiness 
      Scale (ESS), and the items on OSA from the Sleep Disorder Score (SDS) 
      questionnaire were used to select subjects with suspicion of OSA. Polysomnography 
      (PSG) was performed to confirm the diagnosis of OSA. The frequency of MVAs and 
      NMAs was assessed at baseline for the whole sample, and also for the drivers with 
      severe OSA after two years of continuous positive airway pressure (CPAP) 
      treatment. RESULTS: The mean age of the sample was 42.3 +/- 8.3 years. A total of 
      139 (49.1%) subjects had suspected OSA, and the PSG study confirmed the diagnosis 
      in 35.7%. A significant association between OSA severity and NMAs was observed, 
      and subjects with severe OSA showed a near five-fold increased risk of NMAs 
      (OR = 4.745, 95% CI 1.292-17.424, p = 0.019). After two years of CPAP treatment, 
      the rate of NMAs was comparable with drivers without OSA, showing the efficacy of 
      therapy. CONCLUSION: This study showed an unexpected high prevalence of OSA in 
      TDDGs. Untreated subjects with severe OSA had a significantly increased risk of 
      NMAs. In professional drivers, screening, treatment, and management of OSA are 
      mandatory for reducing road accident risk and improving road safety.
CI  - Copyright (c) 2016 Elsevier B.V. All rights reserved.
FAU - Garbarino, Sergio
AU  - Garbarino S
AD  - Sleep Disorder Centre, Department of Neuroscience (DINOGMI), University of Genoa, 
      Genoa, Italy; State Police Health Service Department, Ministry of the Interior, 
      Rome, Italy.
FAU - Guglielmi, Ottavia
AU  - Guglielmi O
AD  - Sleep Disorder Centre, Department of Neuroscience (DINOGMI), University of Genoa, 
      Genoa, Italy.
FAU - Campus, Claudio
AU  - Campus C
AD  - Department of Robotics, Brain and Cognitive Science, Italian Institute of 
      Technology (IIT), Genoa, Italy.
FAU - Mascialino, Barbara
AU  - Mascialino B
AD  - Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 
      Stockholm, Sweden.
FAU - Pizzorni, Domenico
AU  - Pizzorni D
AD  - Refining and Marketing Division, ENI S.P.A., Milan, Italy.
FAU - Nobili, Lino
AU  - Nobili L
AD  - Centre of Epilepsy Surgery, 'C. Munari', Niguarda Hospital, Milan, Italy.
FAU - Mancardi, Gian Luigi
AU  - Mancardi GL
AD  - Sleep Disorder Centre, Department of Neuroscience (DINOGMI), University of Genoa, 
      Genoa, Italy.
FAU - Ferini-Strambi, Luigi
AU  - Ferini-Strambi L
AD  - Department of Clinical Neuroscience, Sleep Disorders Center, Universita 
      Vita-Salute San Raffaele, Milan, Italy. Electronic address: 
      ferinistrambi.luigi@hsr.it.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20160913
PL  - Netherlands
TA  - Sleep Med
JT  - Sleep medicine
JID - 100898759
SB  - IM
EIN - Sleep Med. 2017 Apr;32:287. PMID: 28057498
MH  - Accidents, Traffic/*prevention & control/statistics & numerical data
MH  - Adult
MH  - Automobile Driving/*standards/statistics & numerical data
MH  - *Awareness
MH  - Continuous Positive Airway Pressure/methods
MH  - Disorders of Excessive Somnolence/epidemiology/physiopathology/therapy
MH  - Humans
MH  - Male
MH  - Mass Screening/*methods
MH  - Middle Aged
MH  - Motor Vehicles
MH  - Polysomnography
MH  - Prevalence
MH  - Risk Factors
MH  - Sleep Apnea, Obstructive/*diagnosis/epidemiology/physiopathology/therapy
MH  - Surveys and Questionnaires
OTO - NOTNLM
OT  - Continuous positive airway pressure
OT  - Excessive daytime sleepiness
OT  - Obstructive sleep apnea
OT  - Truck driver health
EDAT- 2016/11/09 06:00
MHDA- 2017/11/29 06:00
CRDT- 2016/11/09 06:00
PHST- 2015/12/04 00:00 [received]
PHST- 2016/03/22 00:00 [revised]
PHST- 2016/05/16 00:00 [accepted]
PHST- 2016/11/09 06:00 [entrez]
PHST- 2016/11/09 06:00 [pubmed]
PHST- 2017/11/29 06:00 [medline]
AID - S1389-9457(16)30153-8 [pii]
AID - 10.1016/j.sleep.2016.05.015 [doi]
PST - ppublish
SO  - Sleep Med. 2016 Sep;25:98-104. doi: 10.1016/j.sleep.2016.05.015. Epub 2016 Sep 
      13.