PMID- 27825607 OWN - NLM STAT- MEDLINE DCOM- 20180706 LR - 20191210 IS - 1934-8150 (Electronic) IS - 1551-7411 (Linking) VI - 13 IP - 6 DP - 2017 Nov TI - Linguistic and psychometric validation of the Malaysian version of Diabetes Quality of Life-Brief Clinical Inventory (DQoL-BCI). PG - 1135-1141 LID - S1551-7411(16)30115-2 [pii] LID - 10.1016/j.sapharm.2016.10.017 [doi] AB - BACKGROUND: Quality of life (QoL) assessment provides valuable outcome to support clinical decision-making, particularly for patients with chronic diseases that are incurable. A brief, 15-item diabetes-specific tool [i.e. Diabetes Quality of Life-Brief Clinical Inventory (DQoL-BCI)] is known to be developed in English and validated for use in clinical practice. This simplified tool, however, is not readily available for use in the Malaysian setting. OBJECTIVE: To translate the DQoL-BCI into a Malaysian version and to assess its construct validity (factorial validity, convergent validity and discriminant validity), reliability (internal consistency) and floor and ceiling effects among the Malaysian diabetic population. MATERIAL AND METHODS: A forward-backward translation, involving professional translators and experts with vast experience in translation of patient reported outcome measures, was conducted. A total of 202 patients with Type 2 diabetes mellitus (T2DM) who fulfilled the inclusion criteria were invited to complete the translated DQoL-BCI. Data were analysed using SPSS for exploratory factor analysis (EFA), convergent and discriminant validity, reliability and test-retest, and AMOS software for confirmatory factor analysis (CFA). RESULTS: Findings from EFA indicated that the 4-factor structure of the Malaysian version of DQoL-BCI was optimal and explained 50.9% of the variance; CFA confirmed the 4-factor model fit. There was negative, moderate correlation between the scores of DQoL-BCI (Malaysian version) and EQ-5D-3L utility score (r = -0.329, p = 0.003). Patients with higher glycated haemoglobin levels (p = 0.008), diabetes macrovascular (p = 0.017) and microvascular (p = 0.013) complications reported poorer QoL. Cronbach's alpha coefficient and intraclass coefficient correlations (range) obtained were 0.703 and 0.86 (0.734-0.934), indicating good reliability and stability of the translated DQoL-BCI. CONCLUSION: This study had validated the linguistic and psychometric properties of DQoL-BCI (Malaysian version), thus providing a valid and reliable brief tool for assessing the QoL of Malaysian T2DM patients. CI - Copyright (c) 2016 Elsevier Inc. All rights reserved. FAU - Samah, Syamimi AU - Samah S AD - Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), 42300, Bandar Puncak Alam, Selangor Darul Ehsan, Malaysia; Collaborative Drug Discovery Research (CDDR) Group, Pharmaceutical and Life Sciences Community of Research, UiTM, 40450, Shah Alam, Selangor Darul Ehsan, Malaysia. FAU - Neoh, Chin Fen AU - Neoh CF AD - Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), 42300, Bandar Puncak Alam, Selangor Darul Ehsan, Malaysia; Collaborative Drug Discovery Research (CDDR) Group, Pharmaceutical and Life Sciences Community of Research, UiTM, 40450, Shah Alam, Selangor Darul Ehsan, Malaysia. Electronic address: neohchinfen@puncakalam.uitm.edu.my. FAU - Wong, Yuet Yen AU - Wong YY AD - Faculty of Pharmacy, UiTM, Bertam Campus, 13200, Kepala Batas, Penang, Malaysia. FAU - Hassali, Mohamed Azmi AU - Hassali MA AD - Discipline of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800, Penang, Malaysia. FAU - Shafie, Asrul Akmal AU - Shafie AA AD - Discipline of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800, Penang, Malaysia. FAU - Lim, Siong Meng AU - Lim SM AD - Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), 42300, Bandar Puncak Alam, Selangor Darul Ehsan, Malaysia; Collaborative Drug Discovery Research (CDDR) Group, Pharmaceutical and Life Sciences Community of Research, UiTM, 40450, Shah Alam, Selangor Darul Ehsan, Malaysia. FAU - Ramasamy, Kalavathy AU - Ramasamy K AD - Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), 42300, Bandar Puncak Alam, Selangor Darul Ehsan, Malaysia; Collaborative Drug Discovery Research (CDDR) Group, Pharmaceutical and Life Sciences Community of Research, UiTM, 40450, Shah Alam, Selangor Darul Ehsan, Malaysia. FAU - Mat Nasir, Nafiza AU - Mat Nasir N AD - Primary Care Medicine Discipline, Faculty of Medicine, UiTM, Selayang Campus, 68100, Batu Caves, Selangor Darul Ehsan, Malaysia. FAU - Han, Yung Wen AU - Han YW AD - Primary Care Medicine Discipline, Faculty of Medicine, UiTM, Selayang Campus, 68100, Batu Caves, Selangor Darul Ehsan, Malaysia. FAU - Burroughs, Thomas AU - Burroughs T AD - Center for Health Outcomes Research (SLUCOR), Saint Louis University, One North Grand, St. Louis, United States. LA - eng PT - Journal Article PT - Validation Study DEP - 20161024 PL - United States TA - Res Social Adm Pharm JT - Research in social & administrative pharmacy : RSAP JID - 101231974 SB - IM CIN - Res Social Adm Pharm. 2017 Mar - Apr;13(2):398. PMID: 27914951 MH - Aged MH - *Diabetes Mellitus, Type 2 MH - Female MH - Humans MH - Language MH - Malaysia MH - Male MH - Middle Aged MH - Psychometrics MH - *Quality of Life MH - *Surveys and Questionnaires OTO - NOTNLM OT - Malaysian OT - Quality of life OT - Reliability OT - Type 2 diabetes mellitus OT - Validity EDAT- 2016/11/09 06:00 MHDA- 2018/07/07 06:00 CRDT- 2016/11/10 06:00 PHST- 2016/06/16 00:00 [received] PHST- 2016/10/18 00:00 [revised] PHST- 2016/10/23 00:00 [accepted] PHST- 2016/11/09 06:00 [pubmed] PHST- 2018/07/07 06:00 [medline] PHST- 2016/11/10 06:00 [entrez] AID - S1551-7411(16)30115-2 [pii] AID - 10.1016/j.sapharm.2016.10.017 [doi] PST - ppublish SO - Res Social Adm Pharm. 2017 Nov;13(6):1135-1141. doi: 10.1016/j.sapharm.2016.10.017. Epub 2016 Oct 24.