PMID- 27833453
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 1426-3912 (Print)
IS  - 1644-4124 (Electronic)
IS  - 1426-3912 (Linking)
VI  - 41
IP  - 3
DP  - 2016
TI  - Benign acute childhood myositis complicating influenza B infection in a boy with 
      idiopathic nephrotic syndrome.
PG  - 328-331
AB  - INTRODUCTION: Benign acute childhood myositis (BACM) is an acute complication of 
      an infection characterized by calf pain, limitation of lower limb mobility, an 
      increase in serum creatine kinase, and a self-limiting course. No reports of BACM 
      in children with idiopathic nephrotic syndrome (INS) can be found in the 
      literature. CASE REPORT: A 5-year-old boy with steroid-sensitive INS presented 
      with fever, leg pain, and problems with walking. Physical examination showed 
      pharyngeal erythema, preserved movements in all joints, and weakness of leg 
      muscles. Laboratory tests showed white blood cell count 3900/microl, albumin 2.3 
      g/dl, urea 25 mg/dl, creatinine 0.3 mg/dl, increased transaminases (AspAT 440 
      U/l, AlAT 100 U/l) and creatine kinase (10 817 U/l), and proteinuria 3500 mg/dl. 
      The boy was diagnosed with an INS bout and BACM. Testing for infective causes of 
      myositis showed evidence of an influenza B virus infection. Treatment included 
      prednisone and oseltamivir. A rapid improvement of motor function was observed, 
      with normalization of serum creatine kinase and transaminases, and resolution of 
      proteinuria. CONCLUSIONS: 1. As influenza virus infection in a child with INS is 
      a risk factor for complications and a disease bout, these patients should be 
      vaccinated against influenza. 2. Differential diagnosis of leg pain and mobility 
      limitation in a child with INS should include lower limb deep venous thrombosis, 
      arthritis, post-infectious neurological complications (including Guillain-Barre 
      syndrome), and BACM. 3. Serum creatine kinase level should be measured in all 
      cases of motor disturbances in a child with symptoms of respiratory tract 
      infection.
FAU - Skrzypczyk, Piotr
AU  - Skrzypczyk P
AD  - Department of Pediatrics and Nephrology, Medical University of Warsaw, Poland.
FAU - Przychodzien, Joanna
AU  - Przychodzien J
AD  - Department of Pediatrics and Nephrology, Medical University of Warsaw, Poland.
FAU - Panczyk-Tomaszewska, Malgorzata
AU  - Panczyk-Tomaszewska M
AD  - Department of Pediatrics and Nephrology, Medical University of Warsaw, Poland.
LA  - eng
PT  - Case Reports
DEP - 20161025
PL  - Poland
TA  - Cent Eur J Immunol
JT  - Central-European journal of immunology
JID - 9702239
PMC - PMC5099392
OTO - NOTNLM
OT  - benign acute childhood myositis
OT  - children
OT  - nephrotic syndrome
EDAT- 2016/11/12 06:00
MHDA- 2016/11/12 06:01
PMCR- 2016/01/01
CRDT- 2016/11/12 06:00
PHST- 2016/06/23 00:00 [received]
PHST- 2016/09/09 00:00 [accepted]
PHST- 2016/11/12 06:00 [entrez]
PHST- 2016/11/12 06:00 [pubmed]
PHST- 2016/11/12 06:01 [medline]
PHST- 2016/01/01 00:00 [pmc-release]
AID - 28586 [pii]
AID - 10.5114/ceji.2016.63135 [doi]
PST - ppublish
SO  - Cent Eur J Immunol. 2016;41(3):328-331. doi: 10.5114/ceji.2016.63135. Epub 2016 
      Oct 25.