PMID- 27834962
OWN - NLM
STAT- MEDLINE
DCOM- 20170718
LR  - 20181113
IS  - 1476-5454 (Electronic)
IS  - 0950-222X (Print)
IS  - 0950-222X (Linking)
VI  - 31
IP  - 3
DP  - 2017 Mar
TI  - Agreement and clinical comparison between a new swept-source optical coherence 
      tomography-based optical biometer and an optical low-coherence reflectometry 
      biometer.
PG  - 437-442
LID - 10.1038/eye.2016.241 [doi]
AB  - PurposeTo compare measurements taken using a swept-source optical coherence 
      tomography-based optical biometer (IOLmaster 700) and an optical low-coherence 
      reflectometry biometer (Lenstar 900), and to determine the clinical impacts of 
      differences in their measurements on intraocular lens (IOL) power 
      predictions.MethodsEighty eyes of 80 patients scheduled to undergo cataract 
      surgery were examined with both biometers. The measurements made using each 
      device were axial length (AL), central corneal thickness (CCT), aqueous depth 
      (AQD), lens thickness (LT), mean keratometry (MK), white-to-white distance (WTW), 
      and pupil diameter (PD). Holladay 2 and SRK/T formulas were used to calculate IOL 
      power. Differences in measurement between the two biometers were determined using 
      the paired t-test. Agreement was assessed through intraclass correlation 
      coefficients (ICC) and Bland-Altman plots.ResultsMean patient age was 76.3+/-6.8 
      years (range 59-89). Using the Lenstar, AL and PD could not be measured in 12.5 
      and 5.25% of eyes, respectively, while IOLMaster 700 took all measurements in all 
      eyes. The variables CCT, AQD, LT, and MK varied significantly between the two 
      biometers. According to ICCs, correlation between measurements made with both 
      devices was excellent except for WTW and PD. Using the SRK/T formula, IOL power 
      prediction based on the data from the two devices were statistically different, 
      but differences were not clinically significant.ConclusionsNo clinically relevant 
      differences were detected between the biometers in terms of their measurements 
      and IOL power predictions. Using the IOLMaster 700, it was easier to obtain 
      biometric measurements in eyes with less transparent ocular media or longer AL.
FAU - Arriola-Villalobos, P
AU  - Arriola-Villalobos P
AUID- ORCID: 0000-0002-3573-0842
AD  - Ophthalmology, Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria 
      del Hospital Clinico San Carlos (IdISSC), Madrid, Spain.
AD  - Patologia ocular del envejecimiento, calidad visual y calidad de vida, Instituto 
      de Salud Carlos III, Madrid, Spain.
FAU - Almendral-Gomez, J
AU  - Almendral-Gomez J
AD  - Ophthalmology, Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria 
      del Hospital Clinico San Carlos (IdISSC), Madrid, Spain.
FAU - Garzon, N
AU  - Garzon N
AD  - Instituto de Oftalmologia Avanzada, Madrid, Spain.
FAU - Ruiz-Medrano, J
AU  - Ruiz-Medrano J
AUID- ORCID: 0000-0002-1105-9265
AD  - Ophthalmology, Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria 
      del Hospital Clinico San Carlos (IdISSC), Madrid, Spain.
FAU - Fernandez-Perez, C
AU  - Fernandez-Perez C
AD  - Investigative Support Unit, Hospital Clinico San Carlos, Instituto de 
      Investigacion Sanitaria del Hospital Clinico San Carlos (IdISSC), Madrid, Spain.
FAU - Martinez-de-la-Casa, J M
AU  - Martinez-de-la-Casa JM
AD  - Patologia ocular del envejecimiento, calidad visual y calidad de vida, Instituto 
      de Salud Carlos III, Madrid, Spain.
AD  - Ophthalmology, Hospital Clinico San Carlos, Departamento de Oftalmologia y ORL, 
      Facultad de Medicina, Universidad Complutense de Madrid, Instituto de 
      Investigacion Sanitaria del Hospital Clinico San Carlos (IdISSC), Madrid, Spain.
FAU - Diaz-Valle, D
AU  - Diaz-Valle D
AD  - Patologia ocular del envejecimiento, calidad visual y calidad de vida, Instituto 
      de Salud Carlos III, Madrid, Spain.
AD  - Ophthalmology, Hospital Clinico San Carlos, Departamento de Oftalmologia y ORL, 
      Facultad de Medicina, Universidad Complutense de Madrid, Instituto de 
      Investigacion Sanitaria del Hospital Clinico San Carlos (IdISSC), Madrid, Spain.
LA  - eng
PT  - Journal Article
DEP - 20161111
PL  - England
TA  - Eye (Lond)
JT  - Eye (London, England)
JID - 8703986
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Anterior Chamber/pathology
MH  - Axial Length, Eye/pathology
MH  - Biometry/*methods
MH  - Cataract/*pathology
MH  - Female
MH  - Humans
MH  - Lens, Crystalline/*pathology
MH  - Lenses, Intraocular
MH  - Male
MH  - Middle Aged
MH  - Reproducibility of Results
MH  - Tomography, Optical Coherence/instrumentation/*methods
PMC - PMC5350368
COIS- The authors declare no conflict of interest.
EDAT- 2016/11/12 06:00
MHDA- 2017/07/19 06:00
PMCR- 2018/03/01
CRDT- 2016/11/12 06:00
PHST- 2016/04/11 00:00 [received]
PHST- 2016/09/07 00:00 [accepted]
PHST- 2016/11/12 06:00 [pubmed]
PHST- 2017/07/19 06:00 [medline]
PHST- 2016/11/12 06:00 [entrez]
PHST- 2018/03/01 00:00 [pmc-release]
AID - eye2016241 [pii]
AID - 10.1038/eye.2016.241 [doi]
PST - ppublish
SO  - Eye (Lond). 2017 Mar;31(3):437-442. doi: 10.1038/eye.2016.241. Epub 2016 Nov 11.