PMID- 27841026
OWN - NLM
STAT- MEDLINE
DCOM- 20170207
LR  - 20170207
IS  - 1715-5320 (Electronic)
IS  - 1715-5312 (Linking)
VI  - 41
IP  - 12
DP  - 2016 Dec
TI  - Concentric and eccentric exercise, glycemic responses to a postexercise meal, and 
      inflammation in women with high versus low waist circumference.
PG  - 1262-1270
AB  - Carbohydrate ingestion and level of concentric versus eccentric muscle activity 
      may alter exercise-induced health benefits for individuals who have high waist 
      circumference as a metabolic risk factor. The purpose of this study was to 
      determine whether metabolic and inflammation responses to an exercise recovery 
      meal differ between women with lower (Lo-WC, <80 cm) compared with higher (Hi-WC) 
      waist circumference when the exercise is primarily concentric (uphill walking; 
      UPHILL) versus primarily eccentric (downhill walking; DOWNHILL). Recreationally 
      active women (age, 18-39 years; body mass index, 19-35.4 m.kg(-2); Lo-WC, n = 13; 
      Hi-WC, n = 10) completed UPHILL, DOWNHILL, and resting (CONTROL) conditions 
      followed 30 min later by a mixed meal tolerance test (MMTT) with carbohydrates to 
      protein ratio of 4:1, and blood glucose, insulin, and inflammation markers were 
      compared across conditions. Compared with Lo-WC, the Hi-WC group had higher (p < 
      0.05) (i) insulin during the MMTT in CONTROL (mean +/- SE; 48.5 +/- 8.2 vs 22.9 +/- 2.8 
      pmol.L(-1)), (ii) baseline (0.7 +/- 0.4 vs 2.0 +/- 1.7 pg.mL(-1)) interleukin-6 
      (IL-6), and (iii) IL-6 responses 8 h after UPHILL and CONTROL. Both groups had 
      (i) increases in IL-6 at 0 h after UPHILL and at 8 h after DOWNHILL, and (ii) 
      lower glycemic responses in UPHILL. Women with Hi-WC had higher IL-6 at rest and 
      delayed increases in IL-6 after a high-carbohydrate meal in all conditions. This 
      is consistent with an inflammation response to the meal and or uphill walking 
      exercise. However, both concentrically and eccentrically biased exercises offered 
      benefits to insulin responses to a high carbohydrate meal for Hi-WC.
FAU - Miles, Mary P
AU  - Miles MP
AD  - Montana State University, Dept. of Health and Human Development, Bozeman, MT 
      59171, USA.
AD  - Montana State University, Dept. of Health and Human Development, Bozeman, MT 
      59171, USA.
FAU - Horrigan, Laura C
AU  - Horrigan LC
AD  - Montana State University, Dept. of Health and Human Development, Bozeman, MT 
      59171, USA.
AD  - Montana State University, Dept. of Health and Human Development, Bozeman, MT 
      59171, USA.
FAU - Jay, Sara E
AU  - Jay SE
AD  - Montana State University, Dept. of Health and Human Development, Bozeman, MT 
      59171, USA.
AD  - Montana State University, Dept. of Health and Human Development, Bozeman, MT 
      59171, USA.
FAU - Brown, Karen M
AU  - Brown KM
AD  - Montana State University, Dept. of Health and Human Development, Bozeman, MT 
      59171, USA.
AD  - Montana State University, Dept. of Health and Human Development, Bozeman, MT 
      59171, USA.
FAU - Porter, Jay W
AU  - Porter JW
AD  - Montana State University, Dept. of Health and Human Development, Bozeman, MT 
      59171, USA.
AD  - Montana State University, Dept. of Health and Human Development, Bozeman, MT 
      59171, USA.
FAU - Steward, Andrea N
AU  - Steward AN
AD  - Montana State University, Dept. of Health and Human Development, Bozeman, MT 
      59171, USA.
AD  - Montana State University, Dept. of Health and Human Development, Bozeman, MT 
      59171, USA.
LA  - eng
PT  - Clinical Trial
PT  - Comparative Study
PT  - Journal Article
DEP - 20160824
PL  - Canada
TA  - Appl Physiol Nutr Metab
JT  - Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition 
      et metabolisme
JID - 101264333
RN  - 0 (Blood Glucose)
RN  - 0 (IL6 protein, human)
RN  - 0 (Insulin)
RN  - 0 (Interleukin-6)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Blood Glucose/analysis
MH  - Body Mass Index
MH  - Cross-Over Studies
MH  - Diet, Carbohydrate Loading/*adverse effects
MH  - *Exercise
MH  - *Feeding Behavior
MH  - Female
MH  - Humans
MH  - Hyperinsulinism/epidemiology/*prevention & control
MH  - Insulin/blood
MH  - *Insulin Resistance
MH  - Interleukin-6/blood
MH  - Meals
MH  - Montana/epidemiology
MH  - Obesity/blood/immunology/physiopathology/*therapy
MH  - Obesity, Abdominal/blood/immunology/physiopathology/*therapy
MH  - Risk Factors
MH  - Waist Circumference
MH  - Walking
MH  - Young Adult
OTO - NOTNLM
OT  - carbohydrate metabolism
OT  - inflammation
OT  - metabolic syndrome
OT  - metabolisme des sucres
OT  - obesity
OT  - obesite
OT  - syndrome metabolique
OT  - tour de taille
OT  - waist circumference
EDAT- 2016/11/15 06:00
MHDA- 2017/02/09 06:00
CRDT- 2016/11/15 06:00
PHST- 2016/11/15 06:00 [pubmed]
PHST- 2017/02/09 06:00 [medline]
PHST- 2016/11/15 06:00 [entrez]
AID - 10.1139/apnm-2016-0281 [doi]
PST - ppublish
SO  - Appl Physiol Nutr Metab. 2016 Dec;41(12):1262-1270. doi: 10.1139/apnm-2016-0281. 
      Epub 2016 Aug 24.