PMID- 27847807 OWN - NLM STAT- MEDLINE DCOM- 20170306 LR - 20181113 IS - 2314-6141 (Electronic) IS - 2314-6133 (Print) VI - 2016 DP - 2016 TI - Comorbidity in Adult Patients Hospitalized with Type 2 Diabetes in Northeast China: An Analysis of Hospital Discharge Data from 2002 to 2013. PG - 1671965 LID - 1671965 AB - This study aims to evaluate the comorbidity burden and patterns among adult patients hospitalized with a diagnosis of type 2 diabetes mellitus (T2DM) in Northeast China using hospital discharge data derived from the electronic medical record database between 2002 and 2013. 12.8% of 4,400,892 inpatients aged >/=18 had a diagnosis of T2DM. Sex differences in prevalence varied among those aged <50, 50-59, and >/=60. Twenty-seven diseases were determined as major comorbidities of T2DM. Essential hypertension was the most common comorbidity of T2DM (absolute cooccurrence risk, 58.4%), while T2DM was also the most popular comorbidity of essential hypertension. Peripheral and visceral atherosclerosis showed the strongest association (relative cooccurrence risk, RCoR 4.206). For five leading comorbidities among patients aged >/=40, male patients had a stronger association with disorders of lipid metabolism than female patients (RCoR 2.779 versus 2.099), and female patients had a stronger association with chronic renal failure than male patients (RCoR 2.461 versus 2.155). Leading comorbidities, except chronic renal failure, had declining associations with T2DM with increased age. Collectively, hospital discharge data can be used to estimate disease prevalence and identify comorbidities. The findings provided comprehensive information on comorbidity patterns, helping policy makers and programs in public health domains to estimate and evaluate the epidemic of chronic diseases. FAU - Chen, Hui AU - Chen H AUID- ORCID: 0000-0003-2256-0861 AD - School of Biomedical Engineering, Capital Medical University, Beijing, China; Beijing Key Laboratory of Fundamental Research on Biomechanics in Clinical Application, Capital Medical University, Beijing, China. FAU - Zhang, Yaoyun AU - Zhang Y AD - School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA. FAU - Wu, Di AU - Wu D AD - Department of Endocrinology, Genetics, and Metabolism, Beijing Children's Hospital, Capital Medical University, Beijing, China. FAU - Gong, Chunxiu AU - Gong C AD - Department of Endocrinology, Genetics, and Metabolism, Beijing Children's Hospital, Capital Medical University, Beijing, China. FAU - Pan, Qing AU - Pan Q AD - School of Biomedical Engineering, Capital Medical University, Beijing, China. FAU - Dong, Xiao AU - Dong X AD - School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA. FAU - Wu, Yonghui AU - Wu Y AD - School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA. FAU - Zhang, Kuan AU - Zhang K AUID- ORCID: 0000-0003-4195-1198 AD - School of Biomedical Engineering, Capital Medical University, Beijing, China; Beijing Key Laboratory of Fundamental Research on Biomechanics in Clinical Application, Capital Medical University, Beijing, China. FAU - Wang, Shiping AU - Wang S AD - Health Information Center, Dalian, Liaoning, China. FAU - Lei, Jianbo AU - Lei J AUID- ORCID: 0000-0002-0807-1407 AD - Health Science Center, Peking University, Beijing, China; School of Medical Informatics and Engineering, Southwest Medical University, Luzhou, Sichuan, China. FAU - Xu, Hua AU - Xu H AUID- ORCID: 0000-0002-5274-4672 AD - School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA. LA - eng PT - Journal Article DEP - 20161025 PL - United States TA - Biomed Res Int JT - BioMed research international JID - 101600173 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Algorithms MH - China/epidemiology MH - Comorbidity MH - Data Collection MH - Databases, Factual MH - Diabetes Mellitus, Type 2/*complications/*epidemiology MH - Electronic Health Records MH - Female MH - Hospitalization/statistics & numerical data MH - Humans MH - Lipid Metabolism MH - Male MH - Middle Aged MH - Models, Statistical MH - *Patient Discharge MH - Risk Factors MH - Sex Factors MH - Young Adult PMC - PMC5099493 EDAT- 2016/11/17 06:00 MHDA- 2017/03/07 06:00 PMCR- 2016/10/25 CRDT- 2016/11/17 06:00 PHST- 2016/05/10 00:00 [received] PHST- 2016/09/01 00:00 [revised] PHST- 2016/09/21 00:00 [accepted] PHST- 2016/11/17 06:00 [entrez] PHST- 2016/11/17 06:00 [pubmed] PHST- 2017/03/07 06:00 [medline] PHST- 2016/10/25 00:00 [pmc-release] AID - 10.1155/2016/1671965 [doi] PST - ppublish SO - Biomed Res Int. 2016;2016:1671965. doi: 10.1155/2016/1671965. Epub 2016 Oct 25.