PMID- 27854123
OWN - NLM
STAT- MEDLINE
DCOM- 20170703
LR  - 20170703
IS  - 1651-2006 (Electronic)
IS  - 1401-7431 (Linking)
VI  - 51
IP  - 2
DP  - 2017 Apr
TI  - A retrospective analysis of cardiovascular outcomes in patients treated with ASV.
PG  - 106-113
LID - 10.1080/14017431.2016.1262546 [doi]
AB  - OBJECTIVES: The effect of long-term adaptive servo-ventilation (ASV) on 
      cardiovascular mortality and admission rates in patients with chronic heart 
      failure (CHF) and Cheyne-Stokes respiration (CSR) has not been much studied. The 
      aim of this study was primarily to investigate whether ASV therapy significantly 
      reduced these parameters. DESIGN: We included 75 CHF patients on optimal 
      medication and CSR >/=25% of sleeping time, in New York Heart Association (NYHA) 
      classes II-IV and left ventricular ejection fraction (LVEF) </= 45%. Thirty-one 
      patients were treated with ASV for >3-18 months and 44 patients served as a 
      control group. RESULTS: Seven deaths (16%) in the control group and one death 
      (3%) in the ASV treatment group had cardiovascular etiology. There was no 
      significant difference between the two groups regarding cardiovascular death (log 
      rank p = 0.07; HR 0.18 (95% CI 0.02-1.44), p = 0.11) and combined cardiovascular 
      death or readmissions, but there was a trend toward better outcome regarding 
      cardiovascular event-free survival (log rank p = 0.06; HR 0.53 (95% CI 
      0.27-1.05). CONCLUSIONS: In CHF patients with CSR, 18 months ASV treatment did 
      not significantly affect cardiovascular death or combined cardiovascular death or 
      hospital admissions. But there was a trend toward better combined outcome.
FAU - Hetland, Arild
AU  - Hetland A
AD  - a The Hospital of Ostfold , Fredrikstad , Norway.
AD  - b University of Oslo , Oslo , Norway.
FAU - Haugaa, Kristina H
AU  - Haugaa KH
AD  - b University of Oslo , Oslo , Norway.
AD  - c Department of Cardiology and Center for Cardiological Innovation, Oslo 
      University Hospital Rikshospitalet , Oslo , Norway.
FAU - Vistnes, Maria
AU  - Vistnes M
AD  - a The Hospital of Ostfold , Fredrikstad , Norway.
AD  - d Department of Internal Medicine , Diakonhjemmet Hospital , Oslo , Norway.
FAU - Liland, Kristian Hovde
AU  - Liland KH
AD  - e Department of Chemistry, Biotechnology and Food Sciences, Norwegian University 
      of Life Sciences , As , Norway.
FAU - Olseng, Margareth
AU  - Olseng M
AD  - a The Hospital of Ostfold , Fredrikstad , Norway.
FAU - Jacobsen, Morten B
AU  - Jacobsen MB
AD  - a The Hospital of Ostfold , Fredrikstad , Norway.
AD  - b University of Oslo , Oslo , Norway.
FAU - Edvardsen, Thor
AU  - Edvardsen T
AD  - b University of Oslo , Oslo , Norway.
AD  - c Department of Cardiology and Center for Cardiological Innovation, Oslo 
      University Hospital Rikshospitalet , Oslo , Norway.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20161207
PL  - England
TA  - Scand Cardiovasc J
JT  - Scandinavian cardiovascular journal : SCJ
JID - 9708377
SB  - IM
MH  - Aged
MH  - Cause of Death
MH  - Cheyne-Stokes Respiration/diagnosis/mortality/physiopathology/*therapy
MH  - Chronic Disease
MH  - Disease Progression
MH  - Disease-Free Survival
MH  - Female
MH  - Heart Failure/diagnosis/mortality/physiopathology/*therapy
MH  - Hemodynamics
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Lung/physiopathology
MH  - Male
MH  - Middle Aged
MH  - Patient Admission
MH  - Proportional Hazards Models
MH  - Respiration, Artificial/adverse effects/*methods/mortality
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Time Factors
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Heart failure
OT  - adaptive servo-ventilation
OT  - mortality
EDAT- 2016/11/18 06:00
MHDA- 2017/07/04 06:00
CRDT- 2016/11/18 06:00
PHST- 2016/11/18 06:00 [pubmed]
PHST- 2017/07/04 06:00 [medline]
PHST- 2016/11/18 06:00 [entrez]
AID - 10.1080/14017431.2016.1262546 [doi]
PST - ppublish
SO  - Scand Cardiovasc J. 2017 Apr;51(2):106-113. doi: 10.1080/14017431.2016.1262546. 
      Epub 2016 Dec 7.