PMID- 27858914
OWN - NLM
STAT- MEDLINE
DCOM- 20170224
LR  - 20210109
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 95
IP  - 44
DP  - 2016 Nov
TI  - Values of hemodynamic variation in response to passive leg raising in predicting 
      exercise capacity of heart failure with preserved ejection fraction.
PG  - e5322
LID - 10.1097/MD.0000000000005322 [doi]
LID - e5322
AB  - In heart failure patients with preserved ejection fraction, their hemodynamic 
      parameters usually change when they are from recumbent to passive leg raising. 
      The authors designed this study to investigate the relationship between 
      hemodynamic parameters measured by impedance cardiography (ICG) and 6-minute walk 
      distance (6MWD) of heart failure with preserved ejection fraction (HFPEF). We 
      recruited 49 subjects with HFPEF in the study, and all the subjects were 
      separated into 2 groups: the patients whose hemodynamic parameters rose after 
      passive leg raising were in group 1 (n = 26) and the patients whose hemodynamic 
      parameters did not rise after passive leg raising were in group 2 (n = 23). Our 
      study then compared the 6MWD, left ventricular ejection fraction, and plasma 
      NT-pro-brain natriuretic peptide between the 2 groups. Group 1 had significantly 
      longer 6MWD than group 2 (515.38 +/- 24.97 vs 306.39 +/- 20.20 m; P = 0.043). 
      Hemodynamic parameters measured by ICG significantly correlated with 6MWD in both 
      groups. Patients whose hemodynamic parameters rose in response to passive leg 
      raising were more likely to have better exercise capacity. Hemodynamic variation 
      in response to passive leg raising measured by ICG may be more sensitive in 
      predicting exercise capacity of patients with HFPEF.
FAU - Zhou, Hong-Lian
AU  - Zhou HL
AD  - Department of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, China.
FAU - Ding, Ling
AU  - Ding L
FAU - Mi, Tao
AU  - Mi T
FAU - Zheng, Kai
AU  - Zheng K
FAU - Wu, Xiao-Fen
AU  - Wu XF
FAU - Wang, Jing
AU  - Wang J
FAU - Liu, Meng-Ying
AU  - Liu MY
FAU - Zhang, Le
AU  - Zhang L
FAU - Zhang, Cun-Tai
AU  - Zhang CT
FAU - Quan, Xiao-Qing
AU  - Quan XQ
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - IM
MH  - Aged
MH  - *Exercise Tolerance
MH  - Female
MH  - Heart Failure/*physiopathology
MH  - *Hemodynamics
MH  - Humans
MH  - Leg/physiopathology
MH  - Male
MH  - Middle Aged
MH  - *Stroke Volume
MH  - *Walking
PMC - PMC5591162
COIS- The authors have no conflicts of interest to disclose.
EDAT- 2016/11/20 06:00
MHDA- 2017/02/25 06:00
PMCR- 2016/11/04
CRDT- 2016/11/19 06:00
PHST- 2016/11/19 06:00 [entrez]
PHST- 2016/11/20 06:00 [pubmed]
PHST- 2017/02/25 06:00 [medline]
PHST- 2016/11/04 00:00 [pmc-release]
AID - 00005792-201611010-00079 [pii]
AID - 10.1097/MD.0000000000005322 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2016 Nov;95(44):e5322. doi: 10.1097/MD.0000000000005322.