PMID- 27861328
OWN - NLM
STAT- MEDLINE
DCOM- 20171020
LR  - 20190318
IS  - 1524-4040 (Electronic)
IS  - 0148-396X (Linking)
VI  - 79 Suppl 1
DP  - 2016 Dec
TI  - Laser Interstitial Thermal Therapy for Mesial Temporal Lobe Epilepsy.
PG  - S83-S91
AB  - Approximately one-third of patients with epilepsy do not achieve adequate seizure 
      control through medical management alone. Mesial temporal lobe epilepsy (MTLE) is 
      one of the most common forms of medically refractory epilepsy referred for 
      surgical management. Stereotactic laser amygdalohippocampotomy using magnetic 
      resonance-guided laser interstitial thermal therapy (MRg-LITT) is an important 
      emerging therapy for MTLE. Initial published reports support MRg-LITT as a less 
      invasive surgical option with a shorter hospital stay and fewer neurocognitive 
      side effects compared with craniotomy for anterior temporal lobectomy with 
      amygdalohippocampectomy and selective amygdalohippocampectomy. We provide a 
      historical overview of laser interstitial thermal therapy development and the 
      technological advancements that led to the currently available commercial 
      systems. Current applications of MRg-LITT for MTLE, reported outcomes, and 
      technical issues of the surgical procedure are reviewed. Although initial reports 
      indicate that stereotactic laser amygdalohippocampotomy may be a safe and 
      effective therapy for medically refractory MTLE, further research is required to 
      establish its long-term effectiveness and its cost/benefit profile. 
      ABBREVIATIONS: ATLAH, anterior temporal lobectomy with 
      amygdalohippocampectomyLITT, laser interstitial thermal therapyMRg-LITT, magnetic 
      resonance-guided laser interstitial thermal therapyMTLE, mesial temporal lobe 
      epilepsySAH, selective amygdalohippocampectomySLAH, stereotactic laser 
      amygdalohippocampotomy.
FAU - Wicks, Robert T
AU  - Wicks RT
AD  - *Department of Neurological Surgery, Wake Forest University School of Medicine, 
      Winston-Salem, North Carolina; double daggerDepartment of Neurosurgery, University of Miami, 
      Miami, Florida;  section signDepartment of Neurosurgery, Emory University, Atlanta, Georgia.
FAU - Jermakowicz, Walter J
AU  - Jermakowicz WJ
FAU - Jagid, Jonathan R
AU  - Jagid JR
FAU - Couture, Daniel E
AU  - Couture DE
FAU - Willie, Jon T
AU  - Willie JT
FAU - Laxton, Adrian W
AU  - Laxton AW
FAU - Gross, Robert E
AU  - Gross RE
LA  - eng
PT  - Historical Article
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Neurosurgery
JT  - Neurosurgery
JID - 7802914
SB  - IM
MH  - Amygdala/surgery
MH  - Epilepsy, Temporal Lobe/*surgery
MH  - History, 20th Century
MH  - History, 21st Century
MH  - Humans
MH  - Hyperthermia, Induced/methods
MH  - Laser Therapy/history/*methods
MH  - Magnetic Resonance Imaging, Interventional
MH  - Neurosurgical Procedures/*methods
MH  - Stereotaxic Techniques
MH  - Temporal Lobe/*surgery
EDAT- 2016/11/20 06:00
MHDA- 2017/10/21 06:00
CRDT- 2016/11/19 06:00
PHST- 2016/11/19 06:00 [entrez]
PHST- 2016/11/20 06:00 [pubmed]
PHST- 2017/10/21 06:00 [medline]
AID - 00006123-201612001-00010 [pii]
AID - 10.1227/NEU.0000000000001439 [doi]
PST - ppublish
SO  - Neurosurgery. 2016 Dec;79 Suppl 1:S83-S91. doi: 10.1227/NEU.0000000000001439.