PMID- 27866847
OWN - NLM
STAT- MEDLINE
DCOM- 20170313
LR  - 20191210
IS  - 1873-376X (Electronic)
IS  - 1570-0232 (Linking)
VI  - 1040
DP  - 2017 Jan 1
TI  - Detection of trans-fatty acids by high performance liquid chromatography coupled 
      with in-tube solid-phase microextraction using hydrophobic polymeric monolith.
PG  - 214-221
LID - S1570-0232(16)31218-1 [pii]
LID - 10.1016/j.jchromb.2016.11.014 [doi]
AB  - Based on in-tube solid-phase microextraction (in-tube SPME) using a hydrophobic 
      poly (octadecyl methacrylate-co-ethylene dimethacrylate) [poly (OMA-co-EDMA)] 
      monolith, a simple high performance liquid chromatography (HPLC) method has been 
      developed for detection of trans-fatty acids (TFAs) as their fatty acid methyl 
      esters (FAMEs). The poly (OMA-co-EDMA) monolithic column with high hydrophobicity 
      was specially prepared for simultaneous microextraction, pre-separation and 
      purification for the analytes. The pre-separation selectivity, the extraction 
      efficiency, and the purification effect for FAMEs were investigated respectively. 
      Furthermore, some operation parameters have been optimized in detail with respect 
      to satisfactory extraction efficiency of the target compounds. Under the 
      optimized conditions, the enrichment factors for model FAMEs were ranged from 
      58.3 to 70.9, wide linear range (0.01-1.00mg/kg) and low detection limits (LODs) 
      (3.0-7.1mug/kg) were achieved, respectively. In addition, recoveries of the method 
      were in the range from 83.0 to 106.4% with low relative standard deviations 
      (RSDs) of 3.2-4.7% (n=4) at spiking levels of 0.05, 0.25 and 0.5mg/kg, 
      respectively. Finally, the proposed method was successfully applied for detection 
      of TFAs in practical samples, which possesses short time-consuming, low 
      disturbance and high detection sensitivity.
CI  - Copyright (c) 2016 Elsevier B.V. All rights reserved.
FAU - Wu, Fangling
AU  - Wu F
AD  - Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou, 
      350002, China; Institute of Laser Chemistry, Department of Chemistry, Fudan 
      University, Shanghai, 200433, China.
FAU - Wang, Jiabin
AU  - Wang J
AD  - Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou, 
      350002, China. Electronic address: jbwang@fzu.edu.cn.
FAU - Zhao, Qi
AU  - Zhao Q
AD  - Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou, 
      350002, China.
FAU - Jiang, Nan
AU  - Jiang N
AD  - Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou, 
      350002, China.
FAU - Lin, Xucong
AU  - Lin X
AD  - Institute of Food Safety and Environment Monitoring, Fuzhou University, Fuzhou, 
      350108, China.
FAU - Xie, Zenghong
AU  - Xie Z
AD  - Institute of Food Safety and Environment Monitoring, Fuzhou University, Fuzhou, 
      350108, China.
FAU - Li, Jianhua
AU  - Li J
AD  - Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou, 
      350002, China.
FAU - Zhang, Qiqing
AU  - Zhang Q
AD  - Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou, 
      350002, China. Electronic address: zhangqiq@126.com.
LA  - eng
PT  - Journal Article
PT  - Validation Study
DEP - 20161110
PL  - Netherlands
TA  - J Chromatogr B Analyt Technol Biomed Life Sci
JT  - Journal of chromatography. B, Analytical technologies in the biomedical and life 
      sciences
JID - 101139554
RN  - 0 (Coffee)
RN  - 0 (Esters)
RN  - 0 (Methacrylates)
RN  - 0 (Trans Fatty Acids)
RN  - 7BK5G69305 (ethylene dimethacrylate)
SB  - IM
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Coffee/*chemistry
MH  - Esterification
MH  - Esters/analysis
MH  - Hydrophobic and Hydrophilic Interactions
MH  - Limit of Detection
MH  - Methacrylates/*chemistry
MH  - Methylation
MH  - Solid Phase Microextraction/*methods
MH  - Trans Fatty Acids/*analysis
OTO - NOTNLM
OT  - HPLC
OT  - In-tube solid-phase microextraction
OT  - Poly (OMA-co-EDMA) monolithic column
OT  - Trans-fatty acids
EDAT- 2016/11/22 06:00
MHDA- 2017/03/14 06:00
CRDT- 2016/11/22 06:00
PHST- 2016/06/27 00:00 [received]
PHST- 2016/10/31 00:00 [revised]
PHST- 2016/11/09 00:00 [accepted]
PHST- 2016/11/22 06:00 [pubmed]
PHST- 2017/03/14 06:00 [medline]
PHST- 2016/11/22 06:00 [entrez]
AID - S1570-0232(16)31218-1 [pii]
AID - 10.1016/j.jchromb.2016.11.014 [doi]
PST - ppublish
SO  - J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Jan 1;1040:214-221. doi: 
      10.1016/j.jchromb.2016.11.014. Epub 2016 Nov 10.