PMID- 27867873 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20231111 IS - 2230-8210 (Print) IS - 2230-9500 (Electronic) IS - 2230-9500 (Linking) VI - 20 IP - 6 DP - 2016 Nov-Dec TI - Prevalence and predictors of depression and anxiety in patients of diabetes mellitus in a tertiary care center. PG - 746-751 AB - BACKGROUND: Diabetes is one of the most common chronic diseases and affects virtually every organ of the human system. Depression and anxiety is common among patients with diabetes and associated with worse diabetes outcomes. AIMS AND OBJECTIVE: To study the prevalence and predictors of depression and anxiety in patients of Type 2 diabetes mellitus (T2DM) in Pt. B.D. Sharma, PGIMS, Rohtak, Haryana, India, a tertiary care center in Northern India. MATERIALS AND METHODS: Four hundred ten consecutive patients having T2DM and 410 healthy controls matched for age and sex attending the endocrine out-patient department of a tertiary care center of Northern India were included in the study. Sociodemographic and relevant clinical variables were collected. They were evaluated for depression and anxiety using Hamilton Depression Rating Scale and Hamilton Anxiety Rating Scale respectively. RESULTS: It was found that a significantly larger proportion of diabetic patients had depression (26.3% vs. 11.2%, P = 0.001), anxiety (27.6% vs. 12.7%, P = 0.001) and comorbid depression and anxiety (21.0% vs. 7.3%, P = 0.001) as compared to healthy controls. Diabetic women had higher depression (17.1% vs. 9.3%) and anxiety (17.6% vs. 10.0%) than men. The major predictors for a severe form of depression and anxiety among T2DM cases were age, female sex, insulin therapy, retinopathy, nephropathy, and ischemic heart disease. CONCLUSION: The present findings reveal that diabetic cases had significantly higher depression and anxiety as compared to healthy controls. The risk factors for depression and anxiety were age, female sex, insulin therapy, and diabetic complications. FAU - Rajput, Rajesh AU - Rajput R AD - Department of Endocrinology and Medicine VI, Pt. B.D. Sharma PGIMS, Rohtak, Haryana, India. FAU - Gehlawat, Pratibha AU - Gehlawat P AD - Department of Psychiatry, Pt. B.D. Sharma PGIMS, Rohtak, Haryana, India. FAU - Gehlan, Deepak AU - Gehlan D AD - Department of Endocrinology and Medicine VI, Pt. B.D. Sharma PGIMS, Rohtak, Haryana, India. FAU - Gupta, Rajiv AU - Gupta R AD - Department of Psychiatry, Pt. B.D. Sharma PGIMS, Rohtak, Haryana, India. FAU - Rajput, Meena AU - Rajput M AD - Department of Community Medicine, Pt. B.D. Sharma PGIMS, Rohtak, Haryana, India. LA - eng PT - Journal Article PL - India TA - Indian J Endocrinol Metab JT - Indian journal of endocrinology and metabolism JID - 101555690 PMC - PMC5105554 OTO - NOTNLM OT - Anxiety OT - depression OT - diabetes mellitus OT - predictors OT - prevalence EDAT- 2016/11/22 06:00 MHDA- 2016/11/22 06:01 PMCR- 2016/11/01 CRDT- 2016/11/22 06:00 PHST- 2016/11/22 06:00 [entrez] PHST- 2016/11/22 06:00 [pubmed] PHST- 2016/11/22 06:01 [medline] PHST- 2016/11/01 00:00 [pmc-release] AID - IJEM-20-746 [pii] AID - 10.4103/2230-8210.192924 [doi] PST - ppublish SO - Indian J Endocrinol Metab. 2016 Nov-Dec;20(6):746-751. doi: 10.4103/2230-8210.192924.