PMID- 2787595
OWN - NLM
STAT- MEDLINE
DCOM- 19890825
LR  - 20190622
IS  - 0002-9149 (Print)
IS  - 0002-9149 (Linking)
VI  - 64
IP  - 4
DP  - 1989 Jul 18
TI  - Radionuclide imaging of myocardial perfusion and viability in assessment of acute 
      myocardial infarction.
PG  - 9B-16B
AB  - Technical advances in radionuclide imaging have important implications for the 
      management of patients with acute myocardial infarction. Single-photon emission 
      computerized tomography with thallium 201 (TI-201) offers greater accuracy than 
      planar imaging in detecting, localizing and sizing myocardial perfusion defects. 
      Use of single-photon emission computerized tomography with TI-201 should allow 
      for a more accurate assessment of prognosis after myocardial infarction. A new 
      radiopharmaceutical, technetium 99-m methoxyisobutyl isonitrile, provides a 
      number of advantages over TI-201, including higher quality images, lack of 
      redistribution, and the ability to assess first-pass ventricular function. 
      Applications of TI-201 and technetium 99-m methoxyisobutyl isonitrile include 
      assessment of arterial patency and myocardial salvage immediately after 
      thrombolytic therapy, detection of resting ischemia after thrombolytic therapy, 
      targeting of subsets of patients for further intervention, and predischarge 
      assessment to predict the future course of patients after an acute myocardial 
      infarction.
FAU - Berman, D S
AU  - Berman DS
AD  - Nuclear Cardiology, Cedars-Sinai Medical Center, Los Angeles, California 90048.
FAU - Kiat, H
AU  - Kiat H
FAU - Maddahi, J
AU  - Maddahi J
FAU - Shah, P K
AU  - Shah PK
LA  - eng
GR  - 17661/PHS HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Am J Cardiol
JT  - The American journal of cardiology
JID - 0207277
RN  - 0 (Fibrinolytic Agents)
RN  - 0 (Nitriles)
RN  - 0 (Organometallic Compounds)
RN  - 0 (Thallium Radioisotopes)
RN  - 7440-26-8 (Technetium)
RN  - 971Z4W1S09 (Technetium Tc 99m Sestamibi)
SB  - IM
MH  - *Coronary Circulation
MH  - Fibrinolytic Agents/therapeutic use
MH  - Humans
MH  - Myocardial Infarction/*diagnostic imaging/physiopathology
MH  - Myocardial Reperfusion
MH  - *Nitriles
MH  - *Organometallic Compounds
MH  - *Technetium
MH  - Technetium Tc 99m Sestamibi
MH  - *Thallium Radioisotopes
MH  - Tomography, Emission-Computed
MH  - Vascular Patency/drug effects
EDAT- 1989/07/18 00:00
MHDA- 1989/07/18 00:01
CRDT- 1989/07/18 00:00
PHST- 1989/07/18 00:00 [pubmed]
PHST- 1989/07/18 00:01 [medline]
PHST- 1989/07/18 00:00 [entrez]
AID - S0002-9149(89)80003-7 [pii]
AID - 10.1016/s0002-9149(89)80003-7 [doi]
PST - ppublish
SO  - Am J Cardiol. 1989 Jul 18;64(4):9B-16B. doi: 10.1016/s0002-9149(89)80003-7.