PMID- 27878618 OWN - NLM STAT- MEDLINE DCOM- 20170710 LR - 20220408 IS - 1432-1262 (Electronic) IS - 0179-1958 (Linking) VI - 32 IP - 4 DP - 2017 Apr TI - Effective and long-term outcome following ligation of the intersphincteric fistula tract (LIFT) for transsphincteric fistula. PG - 583-585 LID - 10.1007/s00384-016-2723-2 [doi] AB - OBJECTIVE: The purpose of this study was to evaluate the efficacy and long-term outcome of the ligation of the intersphincteric fistula tract (LIFT) procedure for transsphincteric fistula-in-ano. METHODS: A total of 43 patients that were treated with LIFT procedure and had a follow-up time of more than 1 year were included. RESULTS: The median age was 37.18 years, and 32 (74.4%) of the patients were male. The median follow-up time was 26.2 months (range 13-63 months). There were 29 (67.4%) uncomplicated transsphincteric fistulas, 10 (23.3%) horseshoe transsphincteric fistulas, and 4 (9.3%) multiple fistulas. Eight (18.5%) patients presented with dehiscence or infection at the intersphincteric wound and were successfully treated with either laying open (n = 5) or local application of silver nitrate (n = 3). The success rate, as determined from the last follow-up time point, was 83.7% (36/43). The mean time to complete failure was 8.6 weeks (range 1-28) in 7 patients. With the exception of these 7 patients, 32/36 (88.9%) patients had a Cleveland Clinic Florida Faecal incontinence score of 0, 3 patients had a score of 1, and 1 had a score of 2. No significant association was found between laying open and incontinence in these partial failure patients. CONCLUSION: The LIFT procedure can be considered an effective sphincter-sparing procedure in the management of transsphincteric fistula with an acceptable long-term outcome. FAU - Chen, Hong-Jin AU - Chen HJ AD - Department of Colorectal Surgery, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, China. FAU - Sun, Gui-Dong AU - Sun GD AD - Department of Colorectal Surgery, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, China. FAU - Zhu, Ping AU - Zhu P AD - Department of Colorectal Surgery, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, China. FAU - Zhou, Zai-Long AU - Zhou ZL AD - Department of Colorectal Surgery, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, China. FAU - Chen, Yu-Gen AU - Chen YG AD - Department of Colorectal Surgery, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, China. FAU - Yang, Bo-Lin AU - Yang BL AD - Department of Colorectal Surgery, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, China. blyang1971@163.com. LA - eng PT - Journal Article DEP - 20161123 PL - Germany TA - Int J Colorectal Dis JT - International journal of colorectal disease JID - 8607899 SB - IM MH - Adult MH - Anal Canal/*surgery MH - Female MH - Humans MH - Ligation MH - Male MH - Middle Aged MH - Rectal Fistula/*surgery MH - Time Factors MH - Treatment Outcome MH - Young Adult OTO - NOTNLM OT - Ligation of intersphincteric fistula tract OT - Long-term outcome OT - Transsphincteric anal fistula EDAT- 2016/11/24 06:00 MHDA- 2017/07/14 06:00 CRDT- 2016/11/24 06:00 PHST- 2016/11/18 00:00 [accepted] PHST- 2016/11/24 06:00 [pubmed] PHST- 2017/07/14 06:00 [medline] PHST- 2016/11/24 06:00 [entrez] AID - 10.1007/s00384-016-2723-2 [pii] AID - 10.1007/s00384-016-2723-2 [doi] PST - ppublish SO - Int J Colorectal Dis. 2017 Apr;32(4):583-585. doi: 10.1007/s00384-016-2723-2. Epub 2016 Nov 23.