PMID- 27881909
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220408
IS  - 1177-5467 (Print)
IS  - 1177-5483 (Electronic)
IS  - 1177-5467 (Linking)
VI  - 10
DP  - 2016
TI  - Comparison of choroidal thickness measurements between spectral-domain OCT and 
      swept-source OCT in normal and diseased eyes.
PG  - 2271-2276
AB  - PURPOSE: Sub-foveal choroidal thickness (SFCT) is affected in many ocular 
      diseases. The aim of this study was to compare SFCT measurements between Topcon 
      3D 2000 spectral-domain optical coherence tomography (SD-OCT) and Topcon 
      swept-source OCT (SS-OCT), with different laser wavelengths, in normal and 
      diseased populations. MATERIALS AND METHODS: This was a prospective, 
      cross-sectional, noninterventional study including 27 normal volunteers and 27 
      participants with retinal disease. OCT scans were performed sequentially and 
      under standardized conditions using both SD-OCT and SS-OCT. The OCT scans were 
      evaluated by two independent graders. Paired t-tests and intraclass correlation 
      coefficients (ICCs) were used to assess the statistically significant difference 
      between SFCT measurements as measured by the two devices. RESULTS: Mean SFCT 
      measurements for all 54 participants were 264.9+/-103.1 mum using SD-OCT (range: 
      47-470 mum) and 278.5+/-110.5 mum using SS-OCT (range: 56-502 mum), with an 
      inter-device ICC of 0.850. Greater variability was noted in the diseased eyes. 
      Inter-device ICCs were 0.870 (95% CI; 0.760-0.924) and 0.840 (95% CI; 
      0.654-0.930) for normal and diseased eyes, respectively. However, the difference 
      was not statistically significant (P=0.132). CONCLUSION: Both machines reliably 
      measure SFCT. Larger studies are needed to confirm these findings.
FAU - Zafar, Sidra
AU  - Zafar S
AD  - Medical College, Aga Khan University Hospital.
FAU - Siddiqui, Ma Rehman
AU  - Siddiqui MR
AD  - Department of Ophthalmology, Shahzad Eye Hospital; South City Hospital, Karachi, 
      Pakistan.
FAU - Shahzad, Rida
AU  - Shahzad R
AD  - Medical College, Aga Khan University Hospital.
LA  - eng
PT  - Journal Article
DEP - 20161114
PL  - New Zealand
TA  - Clin Ophthalmol
JT  - Clinical ophthalmology (Auckland, N.Z.)
JID - 101321512
PMC - PMC5115687
OTO - NOTNLM
OT  - SD-OCT
OT  - SS-OCT
OT  - choroidal imaging
OT  - diseased
OT  - normal
COIS- The authors report no conflicts of interest in this work.
EDAT- 2016/11/25 06:00
MHDA- 2016/11/25 06:01
PMCR- 2016/11/14
CRDT- 2016/11/25 06:00
PHST- 2016/11/25 06:00 [entrez]
PHST- 2016/11/25 06:00 [pubmed]
PHST- 2016/11/25 06:01 [medline]
PHST- 2016/11/14 00:00 [pmc-release]
AID - opth-10-2271 [pii]
AID - 10.2147/OPTH.S117022 [doi]
PST - epublish
SO  - Clin Ophthalmol. 2016 Nov 14;10:2271-2276. doi: 10.2147/OPTH.S117022. eCollection 
      2016.