PMID- 27884152 OWN - NLM STAT- MEDLINE DCOM- 20171212 LR - 20240117 IS - 1532-429X (Electronic) IS - 1097-6647 (Print) IS - 1097-6647 (Linking) VI - 18 IP - 1 DP - 2016 Nov 25 TI - Use of self-gated radial cardiovascular magnetic resonance to detect and classify arrhythmias (atrial fibrillation and premature ventricular contraction). PG - 83 LID - 83 AB - BACKGROUND: Arrhythmia can significantly alter the image quality of cardiovascular magnetic resonance (CMR); automatic detection and sorting of the most frequent types of arrhythmias during the CMR acquisition could potentially improve image quality. New CMR techniques, such as non-Cartesian CMR, can allow self-gating: from cardiac motion-related signal changes, we can detect cardiac cycles without an electrocardiogram. We can further use this data to obtain a surrogate for RR intervals (valley intervals: VV). Our purpose was to evaluate the feasibility of an automated method for classification of non-arrhythmic (NA) (regular cycles) and arrhythmic patients (A) (irregular cycles), and for sorting of common arrhythmia patterns between atrial fibrillation (AF) and premature ventricular contraction (PVC), using the cardiac motion-related signal obtained during self-gated free-breathing radial cardiac cine CMR with compressed sensing reconstruction (XD-GRASP). METHODS: One hundred eleven patients underwent cardiac XD-GRASP CMR between October 2015 and February 2016; 33 were included for retrospective analysis with the proposed method (6 AF, 8 PVC, 19 NA; by recent ECG). We analyzed the VV, using pooled statistics (histograms) and sequential analysis (Poincare plots), including the median (medVV), the weighted mean (meanVV), the total number of VV values (VVval), and the total range (VVTR) and half range (VVHR) of the cumulative frequency distribution of VV, including the median to half range (medVV/VVHR) and the half range to total range (VVHR/VVTR) ratios. We designed a simple algorithm for using the VV results to differentiate A from NA, and AF from PVC. RESULTS: Between NA and A, meanVV, VVval, VVTR, VVHR, medVV/VVHR and VVHR/VVTR ratios were significantly different (p values = 0.00014, 0.0027, 0.000028, 5x10(-9), 0.002, respectively). Between AF and PVC, meanVV, VVval and medVV/VVHR ratio were significantly different (p values = 0.018, 0.007, 0.044, respectively). Using our algorithm, sensitivity, specificity, and accuracy were 93 %, 95 % and 94 % to discriminate between NA and A, and 83 %, 71 %, and 77 % to discriminate between AF and PVC, respectively; areas under the ROC curve were 0.93 and 0.89. CONCLUSIONS: Our study shows we can reliably detect arrhythmias and differentiate AF from PVC, using self-gated cardiac cine XD-GRASP CMR. FAU - Piekarski, Eve AU - Piekarski E AD - Department of Radiology, The Center for Advanced Imaging Innovation and Research (CAI2R), New York University School of Medicine, 660 First Ave, New York, NY, USA. AD - Department of Radiology, Bernard and Irene Schwartz Center for Biomedical Imaging, New York University School of Medicine, New York, NY, USA. FAU - Chitiboi, Teodora AU - Chitiboi T AD - Department of Radiology, The Center for Advanced Imaging Innovation and Research (CAI2R), New York University School of Medicine, 660 First Ave, New York, NY, USA. AD - Department of Radiology, Bernard and Irene Schwartz Center for Biomedical Imaging, New York University School of Medicine, New York, NY, USA. FAU - Ramb, Rebecca AU - Ramb R AD - Department of Radiology, The Center for Advanced Imaging Innovation and Research (CAI2R), New York University School of Medicine, 660 First Ave, New York, NY, USA. AD - Department of Radiology, Bernard and Irene Schwartz Center for Biomedical Imaging, New York University School of Medicine, New York, NY, USA. FAU - Feng, Li AU - Feng L AD - Department of Radiology, The Center for Advanced Imaging Innovation and Research (CAI2R), New York University School of Medicine, 660 First Ave, New York, NY, USA. AD - Department of Radiology, Bernard and Irene Schwartz Center for Biomedical Imaging, New York University School of Medicine, New York, NY, USA. AD - Sackler Institute of Graduate Biomedical Sciences, New York University School of Medicine, New York, NY, USA. FAU - Axel, Leon AU - Axel L AD - Department of Radiology, The Center for Advanced Imaging Innovation and Research (CAI2R), New York University School of Medicine, 660 First Ave, New York, NY, USA. leon.axel@nyumc.org. AD - Department of Radiology, Bernard and Irene Schwartz Center for Biomedical Imaging, New York University School of Medicine, New York, NY, USA. leon.axel@nyumc.org. AD - Sackler Institute of Graduate Biomedical Sciences, New York University School of Medicine, New York, NY, USA. leon.axel@nyumc.org. LA - eng GR - P41 EB017183/EB/NIBIB NIH HHS/United States PT - Evaluation Study PT - Journal Article DEP - 20161125 PL - England TA - J Cardiovasc Magn Reson JT - Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance JID - 9815616 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - *Algorithms MH - Area Under Curve MH - Atrial Fibrillation/classification/*diagnostic imaging/physiopathology MH - *Cardiac-Gated Imaging Techniques MH - *Electrocardiography MH - Feasibility Studies MH - Female MH - Heart Rate MH - Humans MH - Image Interpretation, Computer-Assisted/*methods MH - Magnetic Resonance Imaging, Cine/*methods MH - Male MH - Middle Aged MH - Predictive Value of Tests MH - ROC Curve MH - Respiratory Mechanics MH - Retrospective Studies MH - Ventricular Premature Complexes/classification/*diagnostic imaging/physiopathology MH - Young Adult PMC - PMC5123392 OTO - NOTNLM OT - AF OT - Arrhythmia OT - Atrial fibrillation OT - PVC OT - Premature ventricular contraction OT - RR intervals OT - Self-gated CMR OT - XD-GRASP EDAT- 2016/11/26 06:00 MHDA- 2017/12/13 06:00 PMCR- 2016/11/25 CRDT- 2016/11/26 06:00 PHST- 2016/10/05 00:00 [received] PHST- 2016/11/03 00:00 [accepted] PHST- 2016/11/26 06:00 [entrez] PHST- 2016/11/26 06:00 [pubmed] PHST- 2017/12/13 06:00 [medline] PHST- 2016/11/25 00:00 [pmc-release] AID - S1097-6647(23)01024-4 [pii] AID - 306 [pii] AID - 10.1186/s12968-016-0306-6 [doi] PST - epublish SO - J Cardiovasc Magn Reson. 2016 Nov 25;18(1):83. doi: 10.1186/s12968-016-0306-6.