PMID- 27886800
OWN - NLM
STAT- MEDLINE
DCOM- 20170816
LR  - 20181202
IS  - 1532-1770 (Electronic)
IS  - 1521-6942 (Linking)
VI  - 30
IP  - 2
DP  - 2016 Apr
TI  - Behcet's disease: How to diagnose and treat vascular involvement.
PG  - 279-295
LID - S1521-6942(16)30042-0 [pii]
LID - 10.1016/j.berh.2016.08.002 [doi]
AB  - Behcet's disease is a multisystem disorder with unknown etiology and a unique 
      geographic distribution. The disease is characterized by recurrent skin-mucosa 
      lesions and sight-threatening panuveitis. Vascular involvement, which is more 
      common and more severe among males, has also equally characteristic features such 
      as affecting mostly veins, having a significant tendency for thrombosis, and 
      running a relapsing course. Lower extremity vein thrombosis (LEVT) is the most 
      frequent manifestation, followed by vena cava inferior thrombosis. Pulmonary 
      artery involvement (PAI), the most common form of arterial involvement, manifests 
      as aneurysms and "in situ" thrombosis. PAI and Budd-Chiari syndrome are the 
      leading causes of increased mortality. In vascular cluster, typically, several 
      types of venous or arterial vascular involvement may accumulate in the same 
      individual. LEVT or cerebral venous sinus thrombosis is often present in these 
      subgroups as the first event. Immunosuppressive treatment is essential in 
      preventing the attacks and increasing survival.
CI  - Copyright A(c) 2016 Elsevier Ltd. All rights reserved.
FAU - Seyahi, Emire
AU  - Seyahi E
AD  - University of Istanbul, Cerrahpasa Medical Faculty, Department of Medicine, 
      Division of Rheumatology, Istanbul 81310, Turkey. Electronic address: 
      eseyahi@yahoo.com.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20160916
PL  - Netherlands
TA  - Best Pract Res Clin Rheumatol
JT  - Best practice & research. Clinical rheumatology
JID - 101121149
RN  - 0 (Immunosuppressive Agents)
SB  - IM
MH  - Adult
MH  - Behcet Syndrome/complications/*diagnosis/drug therapy
MH  - Humans
MH  - Immunosuppressive Agents/therapeutic use
MH  - Male
MH  - Thrombosis/etiology
OTO - NOTNLM
OT  - Anticoagulation
OT  - Azathioprine
OT  - Behcet's disease
OT  - Lower extremity vein thrombosis
OT  - Pulmonary artery aneurysms
OT  - Thrombosis
OT  - Vasculitis
OT  - Vena cava thrombosis
EDAT- 2016/11/26 06:00
MHDA- 2017/08/17 06:00
CRDT- 2016/11/26 06:00
PHST- 2016/06/07 00:00 [received]
PHST- 2016/07/27 00:00 [revised]
PHST- 2016/07/27 00:00 [accepted]
PHST- 2016/11/26 06:00 [entrez]
PHST- 2016/11/26 06:00 [pubmed]
PHST- 2017/08/17 06:00 [medline]
AID - S1521-6942(16)30042-0 [pii]
AID - 10.1016/j.berh.2016.08.002 [doi]
PST - ppublish
SO  - Best Pract Res Clin Rheumatol. 2016 Apr;30(2):279-295. doi: 
      10.1016/j.berh.2016.08.002. Epub 2016 Sep 16.