PMID- 27890914
OWN - NLM
STAT- MEDLINE
DCOM- 20170609
LR  - 20220331
IS  - 1474-1741 (Electronic)
IS  - 1474-1733 (Linking)
VI  - 17
IP  - 1
DP  - 2017 Jan
TI  - Dendritic cell migration in health and disease.
PG  - 30-48
LID - 10.1038/nri.2016.116 [doi]
AB  - Dendritic cells (DCs) are potent and versatile antigen-presenting cells, and 
      their ability to migrate is key for the initiation of protective pro-inflammatory 
      as well as tolerogenic immune responses. Recent comprehensive studies have 
      highlighted the importance of DC migration in the maintenance of immune 
      surveillance and tissue homeostasis, and also in the pathogenesis of a range of 
      diseases. In this Review, we summarize the anatomical, cellular and molecular 
      factors that regulate the migration of different DC subsets in health and 
      disease. In particular, we focus on new insights concerning the role of migratory 
      DCs in the pathogenesis of diseases of the skin, intestine, lung, and brain, as 
      well as in autoimmunity and atherosclerosis.
FAU - Worbs, Tim
AU  - Worbs T
AD  - Institute of Immunology, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 
      Hannover, Germany.
FAU - Hammerschmidt, Swantje I
AU  - Hammerschmidt SI
AD  - Institute of Immunology, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 
      Hannover, Germany.
FAU - Forster, Reinhold
AU  - Forster R
AD  - Institute of Immunology, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 
      Hannover, Germany.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20161128
PL  - England
TA  - Nat Rev Immunol
JT  - Nature reviews. Immunology
JID - 101124169
SB  - IM
MH  - Animals
MH  - Autoimmunity/immunology
MH  - Cell Movement/*immunology
MH  - Dendritic Cells/*immunology/*metabolism
MH  - Humans
MH  - Immune Tolerance/immunology
EDAT- 2016/11/29 06:00
MHDA- 2017/06/10 06:00
CRDT- 2016/11/29 06:00
PHST- 2016/11/29 06:00 [pubmed]
PHST- 2017/06/10 06:00 [medline]
PHST- 2016/11/29 06:00 [entrez]
AID - nri.2016.116 [pii]
AID - 10.1038/nri.2016.116 [doi]
PST - ppublish
SO  - Nat Rev Immunol. 2017 Jan;17(1):30-48. doi: 10.1038/nri.2016.116. Epub 2016 Nov 
      28.