PMID- 27894229
OWN - NLM
STAT- MEDLINE
DCOM- 20171019
LR  - 20191023
IS  - 2171-8695 (Electronic)
IS  - 1130-6343 (Linking)
VI  - 40
IP  - n06
DP  - 2016 Nov 1
TI  - [Self-reported experience in patients treated with Hepatitis C direct acting 
      antivirals].
PG  - 569-578
AB  - BACKGROUND AND OBJECTIVE: To learn about and analyze the self-reported treatment 
      experience of HCV patients who started treatment with direct acting antivirals 
      agents (DAA), at a real-time, proactive and integrated into the pharmaceutical 
      care healthcare process, using a prospective questionnaire completed by patients 
      as clinical tool. MATERIAL AND METHODS: Observational and cross-sectional study 
      conducted between April (start of the National Strategic Plan) and December 2015 
      in the Outpatient Pharmacy Service. The questionnaire includes variables related 
      to health related quality of life (HRQOL), adherence, adverse effects (AEs), 
      satisfaction, and usefulness of the Pharmacy Service implemented training 
      program. A descriptive analysis of all variables included in the study was 
      conducted and the influence of different variables analyzed in the degree of 
      adherence and HRQOL. The analysis of the differences was performed using 
      chi-square test and simple logistic regression model for calculation of OR. We 
      use SPSS version 20 program and statistical significance for values of p < 0.05 
      was considered. RESULTS: 155 of the 226 surveys returned, with a response rate of 
      68.6%. Referring to the HRQOL (evaluation of physical and emotional state), 38.7% 
      of patients reports that their physical and emotional state is much better from 
      the start of treatment. The presence of EA and worse global information of their 
      disease was associated with worse physical and emotional state (p < 0.05). 
      Reported adherence was 84.5% and the treatment was evaluated as very good or good 
      by 87% of patients. 52.9% had no adverse effects related to the medication and 
      the training process performed by the specialist pharmacist at the first visit 
      96.7% of patients assessed as very good or good. CONCLUSIONS: Self-reported 
      experience acquired through direct and constant contact with patients provides 
      information on important aspects of treatment. We believe that these tools should 
      be incorporated into pharmaceutical care procedures as a way to maintain 
      continuity in patients direct contact. They also induce patients to a 
      self-assessment of various aspects of their own treatment, which can help achieve 
      greater involvement in it and can contribute to achieve the maximum health 
      outcome in pharmacotherapy.
CI  - Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights 
      reserved.
FAU - Canamares Orbis, Irene
AU  - Canamares Orbis I
AD  - Servicio de Farmacia. Hospital Universitario Infanta Leonor. Madrid. Espana. 
      irene.canamares@gmail.com.
FAU - Saez de la Fuente, Javier
AU  - Saez de la Fuente J
AD  - Servicio de Farmacia. Hospital Universitario Infanta Leonor. Madrid. Espana. 
      irene.canamares@gmail.com.
FAU - Izquierdo Garcia, Elsa
AU  - Izquierdo Garcia E
AD  - Servicio de Farmacia. Hospital Universitario Infanta Leonor. Madrid. Espana. 
      irene.canamares@gmail.com.
FAU - Esteban Alba, Concepcion
AU  - Esteban Alba C
AD  - Servicio de Farmacia. Hospital Universitario Infanta Leonor. Madrid. Espana. 
      irene.canamares@gmail.com.
FAU - Such Diaz, Ana
AU  - Such Diaz A
AD  - Servicio de Farmacia. Hospital Universitario Infanta Leonor. Madrid. Espana. 
      irene.canamares@gmail.com.
FAU - Escobar Rodriguez, Ismael
AU  - Escobar Rodriguez I
AD  - Servicio de Farmacia. Hospital Universitario Infanta Leonor. Madrid. Espana. 
      irene.canamares@gmail.com.
LA  - spa
PT  - Journal Article
PT  - Observational Study
TT  - Experiencia autorreferida en pacientes tratados con antivirales directos frente 
      al virus de la hepatitis C.
DEP - 20161101
PL  - Spain
TA  - Farm Hosp
JT  - Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad 
      Espanola de Farmacia Hospitalaria
JID - 9440679
RN  - 0 (Antiviral Agents)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Ambulatory Care
MH  - Antiviral Agents/*therapeutic use
MH  - Cross-Sectional Studies
MH  - Female
MH  - Hepatitis C/*drug therapy/psychology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Patient Compliance
MH  - Patients
MH  - Prospective Studies
MH  - Quality of Life
MH  - *Self Report
MH  - Young Adult
EDAT- 2016/11/30 06:00
MHDA- 2017/10/20 06:00
CRDT- 2016/11/30 06:00
PHST- 2016/11/30 06:00 [entrez]
PHST- 2016/11/30 06:00 [pubmed]
PHST- 2017/10/20 06:00 [medline]
AID - 10.7399/fh.2016.40.6.10503 [doi]
PST - epublish
SO  - Farm Hosp. 2016 Nov 1;40(n06):569-578. doi: 10.7399/fh.2016.40.6.10503.